- Eplerenone - (https://medlineplus.gov/druginfo/meds/a603004.html )
- Eplerenone : Interaction with Food, Herbs and Alcohol - (https://www.medindia.net/drugs/drug-food-interactions/eplerenone.htm)
- Long-term safety and efficacy of the selective aldosterone blocker eplerenone in patients with essential hypertension - (https://pubmed.ncbi.nlm.nih.gov/14604739/ )
Information about Eplerenone
Generic Name : EplerenoneUp-to-date prescription details regarding Eplerenone are provided here.
Pronunciation : eh-PLER-en-one
Learn the correct pronunciation of the Eplerenone, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.
Therapeutic Classification : Aldosterone Antagonists
Trade Names/Brand Names of Eplerenone
India :
Eplecard (50mg) |
Epleran (50 mg) |
Epleran |
Eptus (25 mg) |
Eplecard (25mg) |
Eptus (50mg) |
Planep (25mg) |
Eptus (25mg)
International :
Inspra
Why is Eplerenone Prescribed? (Indications)
This medication is a mineral corticoid receptor antagonist, prescribed for high blood pressure and heart attack. It blocks the action of aldosterone, which aids in the regulation of blood pressure.When should Eplerenone not be taken? (Contraindications)
Contraindicated in people with severe kidney or liver problem, co-administration with ketoconazole, itraconazole, serum potassium greater than 5.5 mEq/L, type 2 diabetes with microalbuminuria, serum creatinine greater than 2 mg/dL in men or greater than 1.8 mg/dl in women, Creatinine Clearance Rate (Ccr) 30 mL/min or less.What is the dosage of Eplerenone?
Adults: PO- Start with 25 mg every day and titrate to target dose of 50 mg every day within 4 weeks as tolerated by the patient.How should Eplerenone be taken?
It comes as a tablet to take by mouth, with or without food.What are the warnings and precautions for Eplerenone?
• Caution should be exercised in patients with history of diabetes, gout, liver or kidney disease, increased potassium level in blood, any allergy, who are taking other medications, during pregnancy and breastfeeding.• It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.
What are the side effects of Eplerenone?
Metabolic- Increase in blood cholesterol and sugar level.Gastrointestinal- Diarrhea and abdominal pain.
Genitourinary- Presence of albumin in urine.
Respiratory- Cough.
Central Nervous System- Dizziness.
Body as a Whole- Fatigue and influenza-like symptoms.
