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Drospirenone and Estradiol - Indications, Dosage, Side Effects and Precautions

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Information about Drospirenone and Estradiol

Generic Name : Drospirenone and Estradiol
Up-to-date prescription details regarding Drospirenone and Estradiol are provided here.

Pronunciation : droe-SPYE-re-none/ETH-i-nil ES-tra-DYE-ol

Learn the correct pronunciation of the Drospirenone and Estradiol, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


ICD Code : Y42.4 Therapeutic Classification : Contraceptives

Trade Names/Brand Names of Drospirenone and Estradiol

India :


Dronis Tab, Tarana Tab, Yasmin Tab

International :


Yasmin 28

Why is Drospirenone and Estradiol Prescribed? (Indications)

This medication is a combination of 2 hormones (estrogen and progestin), prescribed for preventing pregnancy. It is also used for treating irregular and painful (dysmenorrhea) periods, to decrease blood loss and ovarian cysts.

When should Drospirenone and Estradiol not be taken? (Contraindications)

It should not be used in women who have the following conditions: Kidney or liver impairment, adrenal insufficiency, blood clot defects, stroke, heart disease, high blood pressure, diabetes, headache with neurological symptoms, surgery, breast cancer, uterus cancer, vaginal bleeding, jaundice, suspected pregnancy, heavy smoking and hypersensitivity.

What is the dosage of Drospirenone and Estradiol?

PO- 3 mg drospirenone and 20-mcg ethinylestradiol per tablet: 1 tablet orally per day. Start on first day of menstrual cycle or on the first sunday after menstrual period. Take as directed by your physician.

How should Drospirenone and Estradiol be taken?

It comes as a tablet to take by mouth, once daily.

What are the warnings and precautions for Drospirenone and Estradiol?

• Caution should be exercised in patients with history of blood pressure, high cholesterol, depression, diabetes, swelling, gallbladder problems, migraine, obesity, irregular/missed/very light periods, recent pregnancy and thyroid problems, during pregnancy and breastfeeding.

• Monitor blood sugar level regularly.

• It may cause dark spots over the skin. Avoid exposure to sunlight, otherwise condition may worsen.

What are the side effects of Drospirenone and Estradiol?

Serious- Blood clot events, heart attack, stroke, high blood pressure, gallbladder disease and benign liver tumor.
Most Common- Irregular periods, nausea, vomiting, breast tenderness, headache, fatigue, decreased libido and increased weight.
Genitourinary- Spotting, absence of menstrual cycle, painful menstruation and vaginal infection.
Skin- Darkness of skin, rash, acne and redness.
Central Nervous System- Headache, loss of vision, dizziness, migraine, nervousness, mood changes and intolerance.
Liver- Jaundice.
Miscellaneous- Excessive hair growth and inflammation of pancreas.

What are the other precautions for Drospirenone and Estradiol?

Avoid smoking cigarettes or use of tobacco.

What are the storage conditions for Drospirenone and Estradiol?

Store it at room temperature.
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