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General Information on Drospirenone and Estradiol

Generic Name : Drospirenone and Estradiol

Pronunciation : droe-SPYE-re-none/ETH-i-nil ES-tra-DYE-ol

Latest prescription information about Drospirenone and Estradiol. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y42.4 | Therapeutic Classification : Contraceptives

Trade Names/Brand Names of Drospirenone and Estradiol

India : 

International : 

Yasmin 28

Why is Drospirenone and Estradiol Prescribed? (Indications)

This medication is a combination of 2 hormones (estrogen and progestin), prescribed for preventing pregnancy. It is also used for treating irregular and painful (dysmenorrhea) periods, to decrease blood loss and ovarian cysts. 

When should Drospirenone and Estradiol not to be taken? (Contraindications)

It should not be used in women who have the following conditions: Kidney or liver impairment, adrenal insufficiency, blood clot defects, stroke, heart disease, high blood pressure, diabetes, headache with neurological symptoms, surgery, breast cancer, uterus cancer, vaginal bleeding, jaundice, suspected pregnancy, heavy smoking and hypersensitivity.

What is the dosage of Drospirenone and Estradiol?

PO- 3 mg drospirenone and 20-mcg ethinylestradiol per tablet: 1 tablet orally per day. Start on first day of menstrual cycle or on the first sunday after menstrual period. Take as directed by your physician.

How should Drospirenone and Estradiol be taken?

It comes as a tablet to take by mouth, once daily.

What are the warnings and precautions for Drospirenone and Estradiol?

Caution should be exercised in patients with history of blood pressure, high cholesterol, depression, diabetes, swelling, gallbladder problems, migraine, obesity, irregular/missed/very light periods, recent pregnancy and thyroid problems, during pregnancy and breastfeeding.

Monitor blood sugar level regularly.

It may cause dark spots over the skin. Avoid exposure to sunlight, otherwise condition may worsen.

What are the side effects of Drospirenone and Estradiol?

  Serious: Blood clot events, heart attack, stroke, high blood pressure, gallbladder disease and benign liver tumor.
  Most Common: Irregular periods, nausea, vomiting, breast tenderness, headache, fatigue, decreased libido and increased weight.
  Genitourinary: Spotting, absence of menstrual cycle, painful menstruation and vaginal infection.
  Skin: Darkness of skin, rash, acne and redness.
  Central Nervous System: Headache, loss of vision, dizziness, migraine, nervousness, mood changes and intolerance.
  Liver: Jaundice.
  Miscellaneous: Excessive hair growth and inflammation of pancreas.

What are the other precautions for Drospirenone and Estradiol?

Avoid smoking cigarettes or use of tobacco.

What are the storage conditions for Drospirenone and Estradiol?

Store it at room temperature.

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