Pallavi Singh
Written & Compiled by Pharmacist Pallavi Singh, M. Pharmacy (Pharmacy Practice)
Dr. Simi Paknikar
Medically Reviewed by Dr. Simi Paknikar, MD
Last Updated on Mar 30, 2018
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General Information on Disodium hydrogen citrate

Generic Name : Disodium hydrogen citrate

Pronunciation : Di-SOE-dee-um- Hy-Dro-gen-SIT-rate

Latest prescription information about Disodium hydrogen citrate. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the Indian trade name(s) of the drug and its price list.
Therapeutic Classification : Miscellaneous

Overview of Disodium hydrogen citrate

Disodium hydrogen citrate is a urinary alkalinizer used for the treatment of renal tubular acidosis, to prevent uric acid and cysteine stones, and in the treatment of urinary tract infections.

Why is Disodium hydrogen citrate Prescribed? (Indications)

Disodium hydrogen citrate is a urinary alkalanizer.

It is used for the following conditions:
Renal tubular acidosis (a condition where the blood is acidic due to a kidney problem)
To prevent uric acid and cysteine stones in people predisposed to form the stones in the urinary tract
To treat uterine tract infection, though evidence for the same has not been established 

When should Disodium hydrogen citrate not to be taken? (Contraindications)

Disodium hydrogen citrate should not be used in the following conditions:

Allergy to the drug
High blood pressure (since it contains sodium)
Fluid accumulation in the body (called edema)
Metabolic derangements like high osmolality or increased alkalinity of the blood, low blood calcium levels
Kidney dysfunction

What is the dosage of Disodium hydrogen citrate?

The usual dosage of the syrup in adults is 15 to 30 ml two to three times a day.

How should Disodium hydrogen citrate be taken?

Take after a meal on a full stomach.

What are the warnings and precautions for Disodium hydrogen citrate?

Drink plenty of water while on the medication.
Inform your doctor if you are pregnant or breastfeeding before taking the medication.

What are the side effects of Disodium hydrogen citrate?

  Digestive tract: Diarrhea, stomach pain, nausea, vomiting, bleeding from the stomach or intestines
  Blood: Low blood potassium levels, metabolic alkalosis (increased alkalinity of the blood)
  Others: Increased urination, tiredness

What are the other precautions for Disodium hydrogen citrate?

The liquid forms of the drug contains sugar, it is advised to use with caution in diabetes patients

What are the Drug Interactions of Disodium hydrogen citrate?

Since disodium hydrogen citrate makes the urine alkaline, it may increase the elimination of acidic drugs like salicylates and barbiturates through the urine, thus reducing their effects
It may increase the blood sodium levels especially when taken with drugs like corticosteroids.
Use with caution with diuretics like furosemide since it can cause metabolic disturbances.

What are the storage conditions for Disodium hydrogen citrate?

It should be used stored at room temperature, keep it out of the reach of children

Last Updated : 3/30/2018

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