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Dipotassium Hydrogen Citrate - Indications, Dosage, Side Effects and Precautions

Last Updated on May 11, 2020
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Information about Dipotassium Hydrogen Citrate

Generic Name : Dipotassium Hydrogen Citrate
Pronunciation : Di-po-ta-s-sium hy-dro-gen ci-tra-te
Latest prescription information about Dipotassium Hydrogen Citrate. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the Indian trade name(s) of the drug and its price list.
Therapeutic Classification : Miscellaneous

Trade Names/Brand Names of Dipotassium Hydrogen Citrate


Overview of Dipotassium Hydrogen Citrate

• Dipotassium hydrogen citrate is a urinary alkalinizer used for the treatment of renal tubular acidosis, to prevent uric acid and cysteine stones, and in the treatment of urinary tract infections.

Why is Dipotassium Hydrogen Citrate Prescribed? (Indications)

Dipotassium hydrogen citrate is a urinary alkalanizer. It is used for the following conditions:

• Renal tubular acidosis (a condition where the blood is acidic due to a kidney problem)
• To prevent uric acid and cysteine stones in people predisposed to form the stones in the urinary tract
• To treat uterine tract infection, though evidence for the same has not been established  


When should Dipotassium Hydrogen Citrate not be taken? (Contraindications)

Dipotassium hydrogen citrate is contraindicated in the following conditions:

• Allergy to the drug
• High blood potassium levels (hyperkalemia)
• Metabolic derangements due to conditions like Addison’s disease (reduced function of the adrenal glands), uncontrolled diabetes, acute dehydration
• Severe kidney dysfunction
• Severe heart disease like a recent heart attack (since potassium also slows down the heart)
• Stomach or intestinal ulcers, or conditions that slow down the digestive tract
• Active urinary tract infection

What is the dosage of Dipotassium Hydrogen Citrate?

• The usual dose of the drug in adults is 10 to 20 mEq three times per day.
• The exact dose for you will be decided by your physician.

How should Dipotassium Hydrogen Citrate be taken?

• The medicine should be taken along with meals with a glass of water.

What are the warnings and precautions for Dipotassium Hydrogen Citrate?

• Drink plenty of water while on the medication.
• Inform your doctor if you are pregnant or breastfeeding before taking the medication.

What are the side effects of Dipotassium Hydrogen Citrate?

  Digestive tract: Diarrhea, nausea, stomach pain, vomiting, bleeding from the stomach or intestines
  Blood: High potassium levels in the blood

What are the other precautions for Dipotassium Hydrogen Citrate?

• Dipotassium hydrogen citrate should be used with caution in diabetes patients.

What are the Drug Interactions of Dipotassium Hydrogen Citrate?

• Dipotassium hydrogen citrate should be avoided with other potassium salts, potassium-sparing diuretics, or drugs that increase blood potassium levels like non-steroidal painkillers, ACE inhibitors to prevent high blood potassium levels.

• It should be used with caution in patients on beta blockers since they could result in excessive slowing of the heart.
• It should be avoided with anticholinergic drugs that slow the digestive tract like scopolamine and glycopyrrolate.

• Since dipotassium hydrogen citrate makes the urine alkaline, it may increase the elimination of drugs like salicylates and barbiturates through the urine, thus reducing their effects.

What are the storage conditions for Dipotassium Hydrogen Citrate?

• Store at room temperature, keep out of reach of children.

Last Updated : 3/28/2018

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