Dipotassium hydrogen citrate is a urinary alkalinizer used for the treatment of renal tubular acidosis, to prevent uric acid and cysteine stones, and in the treatment of urinary tract infections.
Dipotassium hydrogen citrate is a urinary alkalanizer. It is used for the following conditions:
Renal tubular acidosis (a condition where the blood is acidic due to a kidney problem)
To prevent uric acid and cysteine stones in people predisposed to form the stones in the urinary tract
To treat uterine tract infection, though evidence for the same has not been established
Dipotassium hydrogen citrate is contraindicated in the following conditions:
Allergy to the drug
High blood potassium levels (hyperkalemia)
Metabolic derangements due to conditions like Addisons disease (reduced function of the adrenal glands), uncontrolled diabetes, acute dehydration
Severe kidney dysfunction
Severe heart disease like a recent heart attack (since potassium also slows down the heart)
Stomach or intestinal ulcers, or conditions that slow down the digestive tract
Active urinary tract infection
The usual dose of the drug in adults is 10 to 20 mEq three times per day.
The exact dose for you will be decided by your physician.
The medicine should be taken along with meals with a glass of water.
Drink plenty of water while on the medication.
Inform your doctor if you are pregnant or breastfeeding before taking the medication.
• Digestive tract: Diarrhea, nausea, stomach pain, vomiting, bleeding from the stomach or intestines
• Blood: High potassium levels in the blood
Dipotassium hydrogen citrate should be used with caution in diabetes patients.
Dipotassium hydrogen citrate should be avoided with other potassium salts, potassium-sparing diuretics, or drugs that increase blood potassium levels like non-steroidal painkillers, ACE inhibitors to prevent high blood potassium levels.
It should be used with caution in patients on beta blockers since they could result in excessive slowing of the heart.
It should be avoided with anticholinergic drugs that slow the digestive tract like scopolamine and glycopyrrolate.
Since dipotassium hydrogen citrate makes the urine alkaline, it may increase the elimination of drugs like salicylates and barbiturates through the urine, thus reducing their effects.
Store at room temperature, keep out of reach of children.