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• Dipotassium hydrogen citrate is a urinary alkalinizer used for the treatment of renal tubular acidosis, to prevent uric acid and cysteine stones, and in the treatment of urinary tract infections.
Dipotassium hydrogen citrate is a urinary alkalanizer. It is used for the following conditions:
• Renal tubular acidosis (a condition where the blood is acidic due to a kidney problem)
• To prevent uric acid and cysteine stones in people predisposed to form the stones in the urinary tract
• To treat uterine tract infection, though evidence for the same has not been established
Dipotassium hydrogen citrate is contraindicated in the following conditions:
• Allergy to the drug
• High blood potassium levels (hyperkalemia)
• Metabolic derangements due to conditions like Addison’s disease (reduced function of the adrenal glands), uncontrolled diabetes, acute dehydration
• Severe kidney dysfunction
• Severe heart disease like a recent heart attack (since potassium also slows down the heart)
• Stomach or intestinal ulcers, or conditions that slow down the digestive tract
• Active urinary tract infection
• The usual dose of the drug in adults is 10 to 20 mEq three times per day.
• The exact dose for you will be decided by your physician.
• The medicine should be taken along with meals with a glass of water.
• Drink plenty of water while on the medication.
• Inform your doctor if you are pregnant or breastfeeding before taking the medication.
• Digestive tract: Diarrhea, nausea, stomach pain, vomiting, bleeding from the stomach or intestines
• Blood: High potassium levels in the blood
• Dipotassium hydrogen citrate should be used with caution in diabetes patients.
• Dipotassium hydrogen citrate should be avoided with other potassium salts, potassium-sparing diuretics, or drugs that increase blood potassium levels like non-steroidal painkillers, ACE inhibitors to prevent high blood potassium levels.
• It should be used with caution in patients on beta blockers since they could result in excessive slowing of the heart.
• It should be avoided with anticholinergic drugs that slow the digestive tract like scopolamine and glycopyrrolate.
• Since dipotassium hydrogen citrate makes the urine alkaline, it may increase the elimination of drugs like salicylates and barbiturates through the urine, thus reducing their effects.
• Store at room temperature, keep out of reach of children.
