This medication is a synthetic estrogen, prescribed for atrophic vaginitis (vaginal inflammation) and kraurosis vulvae.
Contraindicated in patients with breast cancer, abnormal vaginal bleeding, estrogen dependant cancer, blood clot disorders, pregnancy and known hypersensitivity.
The usual dosage range is one or two applicatorsful per day for one or two weeks.
• The applicator has to be screwed on the tube containing cream or place the suppository into the applicator.
• The medicine can be slowly inserted into the vagina either standing with one foot on a chair or lying back with one knee bent.
• Stop the application when it becomes uncomfortable and slowly press the plunger for the release of medicament.
• Remove the applicator and wash with soap water and dry.
• Caution should be exercised in patients with history of asthma, epilepsy, heart or kidney disease, migraine, alcoholism, any allergy, children, elderly, during pregnancy and breastfeeding.
• Avoid alcohol consumption.
• It may cause dizziness, do not drive a car or operate machinery while taking this medication.
• Avoid exposure to sunlight.
• Genitourinary :
Increase in size of uterine fibromyoma, vaginal infection, bleeding, spotting, change in menstrual flow, painful menstruation, premenstrual-like syndrome, absence of menstrual periods, cystitis-like syndrome, breast tenderness, breast enlargement, milk secretion.
• Gastrointestinal : Jaundice, nausea, vomiting, abdominal cramps and bloating.
• Skin : Redness of the skin, eruption, loss of scalp hair, excessive hair growth over the body surface.
• Eyes : Refraction, intolerance to contact lenses.
• Central Nervous System : Mental depression, headache, migraine, dizziness and involuntary muscle movement.
• Miscellaneous : Reduced carbohydrate tolerance, aggravation of porphyria, fluid retention, changes in libido, increase or decrease in weight.
Avoid excess dosage.
Store it at controlled room temperature.
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