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Didanosine - Indications, Dosage, Side Effects and Precautions

Written & Compiled by Anushta Chandrapalan, M.Sc  | Medically Reviewed by The Medindia Medical Review Team
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Information about Didanosine

Generic Name : Didanosine
Pronunciation : Dy-da-nose-in
Latest prescription information about Didanosine. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y41.5 | Therapeutic Classification : Antivirals

Trade Names/Brand Names of Didanosine

India : 

International : 

Videx EC

Why is Didanosine Prescribed? (Indications)

This medication is a reverse transcriptase inhibitor, prescribed for HIV/AIDS either alone or with other antiretroviral drugs.  It works by decreasing the amount of HIV in the blood.


When should Didanosine not be taken? (Contraindications)


What is the dosage of Didanosine?

Daily dose is based on body weight.
Adult: PO- As tab/cap: patients with body weight more than 60kg: 400 mg/day. Patients with body weight less than 60 kg: 250 mg/day.

How should Didanosine be taken?

It comes as a tablet to take by mouth, on en empty stomach.

What are the warnings and precautions for Didanosine?

• Caution should be exercised in patients with history of advanced HIV infection (AIDS), kidney, liver problems, gallstones, nerve problems, high blood cholesterol, any allergy, who are taking other medications, elderly, children especially less than 2 yeas old, during pregnancy and breastfeeding.

Avoid alcohol consumption.

It may cause severe side effects such as severe liver impairment, lactic acidosis in patients who are over weight, and in women. Those patients should consult with their doctor before taking this medication.

Avoid sexual contact with your partner during the treatment to prevent the spread of HIV infection.

Need to perform periodic eye exams.

Monitor liver function, complete blood cell counts, and blood clotting while taking this medication.

What are the side effects of Didanosine?

   Most Common : Inflammation of pancreas, diarrhea, nausea, vomiting, abdominal pain, headache, fatigue, rash, urea in blood, liver failure and blurred vision.

What are the other precautions for Didanosine?

Avoid excess dosage.

What are the storage conditions for Didanosine?

To be stored in a cool place and in an airtight container.

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