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Dextromethorphan and Quinidine - Indications, Dosage, Side Effects and Precautions

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Information about Dextromethorphan and Quinidine

Generic Name : Dextromethorphan and Quinidine
Up-to-date prescription details regarding Dextromethorphan and Quinidine are provided here.

Pronunciation : dex-troe-meth-OR-fan- KWIN-i-deen

Learn the correct pronunciation of the Dextromethorphan and Quinidine, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


Trade Names/Brand Names of Dextromethorphan and Quinidine

International :


Nuedexta

Why is Dextromethorphan and Quinidine Prescribed? (Indications)

This combination medication contains CYP2D6 inhibitor and a sigma-1 receptor agonist, prescribed for pseudobulbar affect (PBA). It is the first drug approved by FDA for the treatment of pseudobulbar affect (PBA).

When should Dextromethorphan and Quinidine not be taken? (Contraindications)

Contraindicated in patients with a prolonged QT interval, congenital long QT syndrome, who are taking monoamine oxidase inhibitors (MAOIs), and hypersensitivity.

What is the dosage of Dextromethorphan and Quinidine?

The recommended starting dose is one capsule daily by mouth for first 7 days, then 2 capsules per day.

How should Dextromethorphan and Quinidine be taken?

It comes as a capsule to take by mouth, as directed by your physician.

What are the warnings and precautions for Dextromethorphan and Quinidine?

• Caution should be exercised in patients with history of heart, liver or kidney disease, high or low blood pressure, decrease in platelets, stroke, Alzheimer’s disease, low blood electrolyte levels, slow heartbeat, trouble in walking, myasthenia gravis, any allergy, who are taking other medications, children, during pregnancy and breastfeeding.

• It may cause dizziness, drowsiness, or blurred vision, do not drive a car or operate machinery and get up slowly from bed while taking this medication.

• It may reduce platelet counts; avoid injury or bruising.

What are the side effects of Dextromethorphan and Quinidine?

Most Common - Muscle spasticity, respiratory failure, abdominal pain, weakness, dizziness, fall, and muscle spasms.
Miscellaneous - Diarrhea, dizziness, cough, vomiting, swelling in the extremities, urinary tract infection, flatulence.

What are the other precautions for Dextromethorphan and Quinidine?

Avoid excess dosage.

What are the storage conditions for Dextromethorphan and Quinidine?

Store it at controlled room temperature (25°C).
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