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Dexrazoxane - Indications, Dosage, Side Effects and Precautions

Last Updated on May 11, 2020
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Information about Dexrazoxane

Generic Name : Dexrazoxane
Pronunciation : dex-ra-ZOX-ane
Latest prescription information about Dexrazoxane. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
Therapeutic Classification : Detoxifying Agents

Trade Names/Brand Names of Dexrazoxane

International- Zinecard.

Why is Dexrazoxane Prescribed? (Indications)

This medication is a cardioprotective agent, prescribed for reducing the risk of heart damage from doxorubicin, an anticancer medication. It works by stopping the chemotherapy medications from damaging the heart and the tissues.


When should Dexrazoxane not be taken? (Contraindications)

It should not be used with non- anthracycline chemotherapy drugs.

What is the dosage of Dexrazoxane?

IV- The recommended dosage ratio is dexrazoxane : doxorubicin 10:1 (eg, 500 mg/m2 dexrazoxane :50 mg/m2 doxorubicin).

How should Dexrazoxane be taken?

It comes as a solution for injection, to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Dexrazoxane?

• Caution should be exercised in patients with history of drug-induced bone marrow depression, kidney or liver impairment, who are taking other medications, any allergy, during pregnancy and breastfeeding.

Monitor kidney or liver function regularly while taking this medication.

What are the side effects of Dexrazoxane?

   Most Common : Hair loss, nausea, vomiting, fatigue, uneasiness, loss of appetite, mouth ulcer, fever, infection, diarrhea, pain at injection site, sepsis, nerve damage, redness, vein inflammation, esophagus inflammation, indigestion, bleeding and hives.

What are the other precautions for Dexrazoxane?

Avoid excess dosage.

What are the storage conditions for Dexrazoxane?

Store it at controlled room temperature (25C).

Information by Medical Specialty


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milonmitra, India

Please the cost in india.

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