This medication is a cardioprotective agent, prescribed for reducing the risk of heart damage from doxorubicin, an anticancer medication. It works by stopping the chemotherapy medications from damaging the heart and the tissues.
It should not be used with non- anthracycline chemotherapy drugs.
IV- The recommended dosage ratio is dexrazoxane : doxorubicin 10:1 (eg, 500 mg/m2 dexrazoxane :50 mg/m2 doxorubicin).
It comes as a solution for injection, to be administered by a healthcare provider into the vein.
• Caution should be exercised in patients with history of drug-induced bone marrow depression, kidney or liver impairment, who are taking other medications, any allergy, during pregnancy and breastfeeding.
• Monitor kidney or liver function regularly while taking this medication.
• Most Common : Hair loss, nausea, vomiting, fatigue, uneasiness, loss of appetite, mouth ulcer, fever, infection, diarrhea, pain at injection site, sepsis, nerve damage, redness, vein inflammation, esophagus inflammation, indigestion, bleeding and hives.
Avoid excess dosage.
Store it at controlled room temperature (25°C).
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