• Desaminooxytocin is also known as demoxytocin used for the treatment of postpartum hemorrhage.

• Desaminooxytocin is used for the treatment of postpartum hemorrhage (excessive bleeding following delivery of the baby), to induce and augment labor and promote lactation. 

Desaminooxytocin is contraindicated in the presence of:

• Fetal distress
• Excess uterine distention
• Unfavorable presentation of the fetus
• Obstructed labor
• More than four previous births or previous surgery on the uterus, or other conditions that could increase the risk of uterine rupture
• Elderly women
• Severe toxemia of pregnancy
• Amniotic fluid embolism
• Placenta previa, where the placenta is attached to a lower than normal position in the uterus

• The recommended dosage for desaminooxytocin is 25 to 50 units buccal tablet every 30 minutes or as necessary.

• The tablet should be kept in the mouth in contact with the mucosa, from where it is absorbed.

• Desaminooxytocin should be avoided during the first and second stages of labor
• The uterine motility and fetal heart rate should be continuously monitored following the administration of the medication.
• Use with caution in women with heart disease.

•  Uterus: Excessive bleeding after childbirth
•  Cardiovascular system: Transient low blood pressure, extremely high blood pressure
•  Central nervous system: Bleed in the brain (subarachnoid hemorrhage)
•  Others: Neonatal jaundice, water retention, allergic reaction

• Avoid over dosage of the medicine.
• Do not use the medicine if the patient is allergic to it.

• Avoid use with prostaglandins and anesthetic drugs.
• The increase in blood pressure caused by sympathetomimetics may be worsened by desaminooxytocin.

• Desaminooxytocin should be should be refrigerated 2°C to 8°C or stored as advised by the manufacturer.