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Denileukin Diftitox - Indications, Dosage, Side Effects and Precautions

Written & Compiled by Anushta Chandrapalan, M.Sc  | Medically Reviewed by The Medindia Medical Review Team
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Information about Denileukin Diftitox

Generic Name : Denileukin Diftitox
Pronunciation : DEN-i-loo-kin DIF-ti-toks
Latest prescription information about Denileukin Diftitox. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y43.3 | Therapeutic Classification : Chemotherapy
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Trade Names/Brand Names of Denileukin Diftitox

International- Ontak.
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Why is Denileukin Diftitox Prescribed? (Indications)

This medication is an anticancer agent, prescribed for lymphoma. It interferes cancer cell growth, which results in the death of the cells.

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When should Denileukin Diftitox not be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Denileukin Diftitox?

IV- The recommended dose is 9 or 18 mcg/kg/day, over 30-60 minutes infusion for 5 consecutive days every 21 days for 8 cycles.

How should Denileukin Diftitox be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Denileukin Diftitox?

• Caution should be exercised in patients with history of heart disease or low blood levels of albumin, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.

It may cause dizziness or lightheadedness, do not drive a car or operate machinery while taking this medication.

Avoid contact with people who have infections.

What are the side effects of Denileukin Diftitox?

   Most Common : Fever, nausea, fatigue, rigors, vomiting, diarrhea, headache, swelling in the extremities, cough, difficulty in breathing and itching.
   Miscellaneous : Back pain, weakness, dizziness, lightheadedness, chest pain and sensory loss.

What are the other precautions for Denileukin Diftitox?

Avoid excess dosage.

What are the storage conditions for Denileukin Diftitox?

Store the medication at or below -10 C.




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