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General Information on Deferasirox

Generic Name : Deferasirox

Pronunciation : de FER a sir ox

Latest prescription information about Deferasirox. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
Therapeutic Classification : Chelating Agents

Trade Names/Brand Names of Deferasirox

India : 

International : 

Exjade

Why is Deferasirox Prescribed? (Indications)

This medication is an iron-chelating agent, prescribed for transfusional hemosiderosis (excess iron due to blood transfusions). It works by attaching to iron in the body so that it can be excreted in feces.

When should Deferasirox not to be taken? (Contraindications)

Contraindicated in patients with severe kidney problem, abnormal decrease in platelet counts, bone marrow depression, and hypersensitivity.

What is the dosage of Deferasirox?

PO- The recommended initial daily dose is 20-mg/kg body weight.

How should Deferasirox be taken?

It comes as a tablet to take by mouth, on an empty stomach once a day.

What are the warnings and precautions for Deferasirox?

Caution should be exercised in patients with history of cancer, blood or bone marrow depression, decrease in platelets, vision problem, hearing problem, infection, dehydration, kidney, liver, or stomach problem, elderly, any allergy, who are taking other medications, during pregnancy and breastfeeding.

It may cause dizziness, do not drive a car or operate machinery while taking this medication.

Monitor liver and kidney function, blood protein and iron levels, vision, hearing, and complete blood cell counts regularly while taking this medication.

It may lead to dehydration; drink plenty of fluid to avoid this problem.

What are the side effects of Deferasirox?

   Most Common : Abdominal pain, nausea, vomiting, diarrhea and skin rash.
   Genitourinary : Presence of protein in urine.
  Miscellaneous: Fluid retention, dizziness, anxiety, fever, fatigue, throat pain, hearing loss, and gastrointestinal bleeding.
  Less Common: Liver failure.

What are the other precautions for Deferasirox?

Avoid excess dosage.

What are the storage conditions for Deferasirox?

Store it at controlled room temperature (1530C). Protect from moisture.

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