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Cyclosporine - Indications, Dosage, Side Effects and Precautions

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Cyclosporine Medication Information

Learn everything you need to know about Cyclosporine-pronunciation, uses, dosage guidelines, indications, and when to take or avoid it.

Get up-to-date information on side effects, precautions, warnings, and proper storage to ensure safe usage.

Explore Cyclosporine brand names commonly used in India and internationally, along with detailed pricing information. Consult your healthcare provider for tailored medical advice.

Generic Name : Cyclosporine
Pronunciation : sye' kloe spor een
ICD Code : Y43.4 Therapeutic Classification : Immunosuppressants

Brand Names or Trade Names of Cyclosporine

India :

International :


Gengraf, Neoral, Sandimmune.

Why is Cyclosporine Prescribed? (Indications)

This medication is an immunosuppressant, prescribed for prevention of organ rejection during transplantation. It is also used for psoriasis, rheumatoid arthritis, and uveitis. It works by suppressing the immune system.

When should Cyclosporine not be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Cyclosporine?

Adult- PO- The recommended initial dose range is 10 to 15mg/kg/day. Maintenance: 2 to 6mg/kg/day.

How should Cyclosporine be taken?

It comes as a capsule and suspension to take by mouth. It also comes as a solution for injection to be administered by a healthcare provider into the vein. It also comes as eye drops to instill into the affected eyes.

What are the warnings and precautions for Cyclosporine?

• Caution should be exercised in patients with liver, kidney, brain or nerve problems, changes in blood mineral and cholesterol levels, high blood pressure, cancer, gout, infection, recent vaccination, any allergy, who are taking other medications, during pregnancy and breast feeding.

• It may cause dizziness, do not drive a car or operate machinery while taking this medication.

• Patient may develop with increased risk of Nephrotoxicity, skin cancer; wear protective clothing during outdoors.

• Avoid vaccination during the treatment period.

• This medication may reduce platelet counts; avoid injury or bruising.

Avoid eating Grapefruit or drinking Grapefruit juice while taking this medication.

What are the side effects of Cyclosporine?

Most Common - Kidney dysfunction, tremor and high blood pressure.
Heart - Cramps.
Skin - Abnormal growth of hair over the body surface.
Central Nervous System - Convulsions and headache.
Gastrointestinal - Overgrowth of gums, diarrhea, nausea/vomiting, liver damage and abdominal discomfort.
Autonomic Nervous System - Tingling and flushing.
Blood - Decrease in white blood cells and cancer in lymph nodes.
Respiratory - Sinusitis.
Miscellaneous - Breast enlargement in males.

What are the other precautions for Cyclosporine?

Monitor blood sugar regularly while taking this medication.

What are the storage conditions for Cyclosporine?

Store it at room temperature (25°C), and in an airtight container.

Cyclosporine: Immunosuppressive Drug to Prevent Organ Transplant Rejection


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