Capecitabine - Indications, Dosage, Side Effects and Precautions


Information about Capecitabine

Generic Name : Capecitabine
Up-to-date prescription details regarding Capecitabine are provided here.

Pronunciation : Cap-eh-SIT-uh-bean

Learn the correct pronunciation of the Capecitabine, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.

Trade Names/Brand Names of Capecitabine

India :

International :


Why is Capecitabine Prescribed? (Indications)

This medication is an antimetabolite, prescribed for breast cancer and colorectal cancer. It prevents the growth of cancer cells.

When should Capecitabine not be taken? (Contraindications)

Contraindicated in patients with kidney problems or dihydropyrimidine dehydrogenase (DPD) enzyme deficiency and hypersensitivity.

What is the dosage of Capecitabine?

The recommended dose is 1250 mg/m2 administered orally twice daily (morning and evening; equivalent to 2500 mg/m2 total daily dose) for 2 weeks followed by 1-week rest period given as 3-week cycles.

How should Capecitabine be taken?

It comes as a tablet to take by mouth, with food, two times per day.

What are the warnings and precautions for Capecitabine?

• Caution should be exercised in patients with history of heart, liver or kidney disease, any allergy, bone marrow problems, pain, redness, swelling, tingling, tenderness of the palms and soles, who are taking other medications, elderly, children, during pregnancy and lactation.

• Avoid vaccination while taking this medication.

• It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.

• It may reduce platelet counts; avoid bruising or injury.

• Monitor blood counts and blood electrolytes while taking this medication.

What are the side effects of Capecitabine?

Gastrointestinal Disorders - Diarrhea, nausea, mouth ulcer, vomiting, abdominal pain, gastrointestinal hemorrhage constipation, upper abdominal pain and indigestion.
Skin - Hand-and-Foot Syndrome, hair loss, rash and redness.
General - Injection site pain, irritation, swelling, fatigue, fever, chest pain, back pain, weakness and lethargy.
Central Nervous System - Dizziness, depression, sleep disorders, headache and abnormal taste.
Metabolic - Loss of appetite.
Eye - Eye inflammation and loss of vision.
Blood - Decreased white blood cells.
Respiratory - Nosebleed, cough and sore throat.

What are the other precautions for Capecitabine?

Avoid excess dosage.

What are the storage conditions for Capecitabine?

Store it at room temperature 25oC.
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