- Blood pressure effects of sodium-glucose co-transport 2 (SGLT2) inhibitors - (https://pubmed.ncbi.nlm.nih.gov/24631482/)
- Factors Affecting Canagliflozin-Induced Transient Urine Volume Increase in Patients with Type 2 Diabetes Mellitus - (https://pubmed.ncbi.nlm.nih.gov/27981497/)
- Fixed-Dose Combination of Canagliflozin and Metformin for the Treatment of Type 2 Diabetes: An Overview - (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216068/)
- Canagliflozin - (https://www.ncbi.nlm.nih.gov/books/NBK500623/#:~:text=Canagliflozin%20is%20an%20uncharged%20molecule,to%20the%20infant's%20developing%20kidney.)
- Chronic Kidney Disease and SGLT2 Inhibitors: A Review of the Evolving Treatment Landscape - (https://pubmed.ncbi.nlm.nih.gov/34846711/)
Canagliflozin Medication Information
Get detailed information on Canagliflozin, including pronunciation, uses, dosage guidelines, indications, and instructions on how and when to take it and when to avoid it.
The updated prescription information on Canagliflozin provides an overview of possible side effects, precautions, warnings, and storage tips.
You'll also find brand names used in india and internationally, along with pricing details. For further clarification, consult your healthcare provider.
Generic Name : Canagliflozin Therapeutic Classification : AntidiabeticsTrade Names/Brand Names of Canagliflozin
International :
Invokana
Why is Canagliflozin Prescribed? (Indications)
This medication is an antidiabetic (sodium glucose co-transporter 2 (SGLT2) inhibitor), prescribed for type 2 diabetes mellitus along with diet and exercise. For patients with type 2 diabetes along with diabetic kidney disease, physicians should consider using an SGLT2 inhibitor when the eGFR is at or above 30, especially with albuminuria above 300 mg/g, to lower renal and CV risk as per A.D.A recommendations.When should Canagliflozin not be taken? (Contraindications)
Contraindicated in patients with severe kidney impairment, ESRD, or on dialysis and known hypersensitivity.What is the dosage of Canagliflozin?
PO- The recommended initial dose is 100 mg once daily.How should Canagliflozin be taken?
It comes as a tablet to take by mouth, should be taken before the first meal of the day.What are the warnings and precautions for Canagliflozin?
• Caution should be exercised in patients with history of kidney or liver problems, any allergy, who are taking other medications, elderly, during pregnancy and breastfeeding.• Monitor kidney functions, potassium levels regularly while taking this medication; correct hypovolaemia (decreased blood volume) in patients with kidney impairment, the elderly and in patients with low systolic blood pressure.
• Patient may develop with increased risk of genital mycotic infections and increased LDL; if it is so consult with your healthcare provider.
What are the side effects of Canagliflozin?
Most Common - Female genital mycotic infections, urinary tract infection and increased urination.Gastrointestinal - Increased thirst, constipation, nausea and vomiting.
