This medication is an anti-neoplstic agent (kinase inhibitor), prescribed for medullary thyroid cancer. It stops the growth of cancer cells by by blocking Tyrosine kinases.
The recommended dose is 140 mg orally, once daily.
It comes as a capsule to take by mouth, on an empty stomach.
• Caution should be exercised in patients with history of high blood pressure, coughing up blood or bleeding, open wound, liver problems, any allergy, who are taking other medications, during pregnancy and breastfeeding.
• Patient may develop severe bleeding episodes (serious effects) that can lead to death. If it is so consult with your healthcare provider.
• Stop this medication immediately if you have experienced any one of the following: fistula formation, severe hemorrhage, heart attack, stroke, nephrotic syndrome, osteonecrosis of the jaw and leukoencephalopathy syndrome.
• Most Common :
Diarrhea, mouth ulcer, palmar-plantar erythrodysesthesia syndrome (PPES), decreased weight, decreased appetite, nausea, fatigue, mouth pain, hair color changes, taste disorder, high blood pressure, abdominal pain, and constipation.
• Serious Effects : Coughing up blood or blood clots, blood vomiting, black stools, unusual bleeding.
Avoid excess dosage.
Store it at room temperature (20°C to 25°C).
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