This combination medication is a narcotic partial agonist-antagonist, prescribed for opioid dependency. Naloxone blocks the effects of buprenorphine, which cause withdrawal symptoms in a person with an opioid addiction.
Sublingual- The recommended target dosage is 16/4 mg/day (buprenorphine/naloxone) as a single daily dose. It may be increased or decreased if needed.
It comes as a tablet to be placed under the tongue, with or without food.
• Caution should be exercised in patients with history of slow breathing, drowsiness, stomach problems, diarrhea, head injury, stroke, mental illness, suicidal thoughts, lung or other breathing problem (chronic obstructive pulmonary disease [COPD]), changes in blood electrolytes level, enlarged prostate, urinary obstruction, seizures, liver or kidney disease, any allergy, who are taking other medications, during pregnancy and breastfeeding.
• It may cause drowsiness or dizziness, do not drive a car or operate machinery and get up slowly from bed while taking this medication.
• Avoid alcohol consumption.
• It should not be used in children less than 16 years old.
• Most Common :
Constipation, swollen tongue, vomiting, intoxication, attention deficiency, palpitations, sleeplessness, withdrawal syndrome, acidity and blurred vision.
• Body as a Whole : Weakness, chills, headache, infection, abdominal pain, back pain and withdrawal syndrome.
• Heart : Dilatation blood vessels.
• Gastrointestinal : Diarrhea and nausea.
• Respiratory : Nose inflammation.
• Skin : Increased sweating.
Avoid excess dosage.
Store it at room temperature (25°C).
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