Brivaracetam is an anticonvulsant or antiepileptic drug which is used for the treatment of partial onset seizures along with other medications. This type of seizure usually affects only one part of the brain. The drug mainly acts by reducing the electrical activity of the brain. It is prescribed for people above 16 years of age.
Brivaracetam is contraindicated in patients who are allergic to the drug. It should also be avoided in patients with a history of kidney or liver disease, depression or suicidal thoughts, with alcohol and during pregnancy or breastfeeding.
The usual recommended dose of brivaracetam is 50mg to be taken twice a day orally. It can also be administered as an infusion into the vein over 2 to 15 minutes.
Brivaracetam comes in the form of a tablet or an oral solution to take by mouth. It can be taken either with or without food. Swallow the tablet as a whole, do not crush or chew the tablet. It can also be administered intravenously through a vein by a healthcare provider.
• Do not take the drug if you are planning to your pregnancy as it might harm the fetus.
• Consuming alcohol while taking brivaracetam may result in reduced attention, memory and psychomotor activity.
• Do not drive a car or operate machinery while taking brivaracetam as the drug may cause dizziness, drowsiness or other central nervous system-related symptoms.
• Digestive System: Constipation, nausea, vomiting.
• Central Nervous System: Hallucinations, delusions (strange thoughts which are not in a reality), changes in mood, dizziness, drowsiness, anxiety, irritability, problems with balance and co-ordination, tiredness.
• Respiratory System: Difficulty in breathing, changes in voice.
• Brivaracetam may sometimes result in suicidal ideation. A physician must be immediately consulted if there is any sign of behavioral changes.
• Do not take more than the prescribed dose of the drug or share it with anyone as it may lead to addiction.
Brivaracetam should be avoided with:
• Rifampicin can reduce the plasma concentration of brivaracetam.
• Brivaracetam increases the concentration of phenytoin and the active metabolite of carbamazepine.
Store the medicine in a tightly closed container at room temperature. Protect from excess heat and moisture. Keep out of reach of children.
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