This medication is a monoclonal antibody, prescribed for certain types of lymphoma (Hodgkin lymphoma, systemic anaplastic large cell lymphoma [sALCL]). It works by killing cancer cells.
IV- The recommended dose is 1.8 mg/kg, over 30 minutes infusion every 3 weeks.
It comes as a solution for injection, to be administered by a healthcare provider into the vein.
• Caution should be exercised in patients with history of nerve problem, any allergy, who are taking other medications, during pregnancy and breastfeeding.
• It may cause dizziness, do not drive a car or operate machinery while taking this medication.
• It may decrease platelet counts; avoid injury or bruising.
• Avoid contact with people who have infections that may spread to others.
• Patient may develop with increased risk of tumor lysis syndrome (TLS), and viral brain infection (fatal conditions) with the following symptoms: irregular heartbeat, fainting, decreased urination, muscle weakness or cramps, dizziness, difficulty in talking, poor eyesight, nausea, vomiting, diarrhea, or loss of appetite; if it is so consult with your healthcare provider.
• Most Common :
Decrease in white blood cells, anemia, peripheral sensory neuropathy, fatigue, nausea, fever, rash, diarrhea and pain.
• Blood : Swelling of lymph nodes and decrease in platelet counts.
• Central Nervous system : Headache, sleeplessness, anxiety and dizziness.
• General : Chills and swelling in the extremities.
• Infections : Upper respiratory tract infection.
• Gastrointestinal : Abdominal pain, vomiting and constipation.
• Skin : Itching, hair loss, night sweats and dry skin.
• Respiratory : Cough, difficulty in breathing and throat pain.
• Musculoskeletal : Joint pain, muscle pain, back pain and muscle spasms.
• Metabolic : Decreased appetite and weight.
Avoid excess dosage.
Store vial at 2-8°C.
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