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Brentuximab Vedotin - Indications, Dosage, Side Effects and Precautions

Last Updated on May 11, 2020
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Information about Brentuximab Vedotin

Generic Name : Brentuximab Vedotin
Pronunciation : bren-TUX-i-mab
Latest prescription information about Brentuximab Vedotin. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y43.3 | Therapeutic Classification : Chemotherapy

Trade Names/Brand Names of Brentuximab Vedotin

International- Adcetris.

Why is Brentuximab Vedotin Prescribed? (Indications)

This medication is a monoclonal antibody, prescribed for certain types of lymphoma (Hodgkin lymphoma, systemic anaplastic large cell lymphoma [sALCL]).  It works by killing cancer cells.


When should Brentuximab Vedotin not be taken? (Contraindications)


What is the dosage of Brentuximab Vedotin?

IV- The recommended dose is 1.8 mg/kg, over 30 minutes infusion every 3 weeks.

How should Brentuximab Vedotin be taken?

It comes as a solution for injection, to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Brentuximab Vedotin?

• Caution should be exercised in patients with history of nerve problem, any allergy, who are taking other medications, during pregnancy and breastfeeding.

It may cause dizziness, do not drive a car or operate machinery while taking this medication.

It may decrease platelet counts; avoid injury or bruising.

Avoid contact with people who have infections that may spread to others.

Patient may develop with increased risk of tumor lysis syndrome (TLS), and viral brain infection (fatal conditions) with the following symptoms: irregular heartbeat, fainting, decreased urination, muscle weakness or cramps, dizziness, difficulty in talking, poor eyesight, nausea, vomiting, diarrhea, or loss of appetite; if it is so consult with your healthcare provider.

What are the side effects of Brentuximab Vedotin?

   Most Common : Decrease in white blood cells, anemia, peripheral sensory neuropathy, fatigue, nausea, fever, rash, diarrhea and pain.
   Blood : Swelling of lymph nodes and decrease in platelet counts.
   Central Nervous system : Headache, sleeplessness, anxiety and dizziness.
   General : Chills and swelling in the extremities.
   Infections : Upper respiratory tract infection.
   Gastrointestinal : Abdominal pain, vomiting and constipation.
   Skin : Itching, hair loss, night sweats and dry skin.
   Respiratory : Cough, difficulty in breathing and throat pain.
   Musculoskeletal : Joint pain, muscle pain, back pain and muscle spasms.
   Metabolic : Decreased appetite and weight.

What are the other precautions for Brentuximab Vedotin?

Avoid excess dosage.

What are the storage conditions for Brentuximab Vedotin?

Store vial at 2-8C.

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Biorex, India

is it available in india

Yashesh, India

what is the price of this drug brentuximab vedotin(Adcetris)

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