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Bezafibrate - Indications, Dosage, Side Effects and Precautions

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Information about Bezafibrate

Generic Name : Bezafibrate
Pronunciation : bezz-uh-FIBE-rate
Latest prescription information about Bezafibrate. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y52.6 | Therapeutic Classification : Antilipemics
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Trade Names/Brand Names of Bezafibrate

India : 

International : 

Abeita, Befarlart SR, Béfizal, Besastar SR, Bexalcor, Bezachole, Bezafibrat Arcana, Bezafibrat Heumann, Bezafibrat-1A Pharma, Bezafibrate SR
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Why is Bezafibrate Prescribed? (Indications)

This medication is a fibrate drug, prescribed for high cholesterol in blood. It works mainly by stimulating the action of two enzymes.
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When should Bezafibrate not be taken? (Contraindications)

Contraindicated in patients with liver disease, gallstones or gallbladder disorders; severe kidney insufficiency, decreased albumin level in blood, pregnancy and lactation.

What is the dosage of Bezafibrate?

Adult: PO- 200 mg 3 times/day. Maintenance: 200 mg twice daily. Extended release 400 mg/day.

How should Bezafibrate be taken?

It comes as a tablet to take by mouth; it should be taken with food.

What are the warnings and precautions for Bezafibrate?

• Avoid smoking and alcohol consumption while taking this medication.

• Avoid excess dosage.

• Patient may develop with muscle weakness, if it is so consult with your doctor.

• Caution should be exercised in patients with kidney, liver, heart disease and any form of allergies.

What are the side effects of Bezafibrate?

  Most Common: Gastrointestinal upset, nausea, vomiting, itching, hives, muscle pain, dizziness, hair loss, impotence, fainting, fatigue and increase in liver enzymes.

What are the other precautions for Bezafibrate?

Take cholestyramine in 2 hours interval while taking this medication.

What are the storage conditions for Bezafibrate?

Oral: Store it at controlled room temperature (25°C), and in an airtight container. Keep away from children.

Schedule : H
Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.
Learn more about Bezafibrate's interaction with Alcohol



Bezafibrate : Frequently Asked Questions

Q: Is Bezafibrate a statin?

A: Bezafibrate is not a statin. Bezafibrate is used with statins to lower the cholesterol levels. The combination of bezafibrate and statin therapy is more effective in achieving comprehensive lipid control and lowering  cardiovascular risk(1 Trusted Source
Bezafibrate and simvastatin combination therapy for diabetic dyslipidaemia: efficacy and safety

Go to source
).

Q: Does Bezafibrate affect liver?

A: Bezafibrate has been shown to drastically lower the level of biliary enzymes in various chronic liver illnesses and may be useful for the treatment of certain liver disease(2 Trusted Source
Bezafibrate may attenuate biliary damage associated with chronic liver diseases accompanied by high serum biliary enzyme levels

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).

Q: Does Bezafibrate reduces heart rate?

A: Bezafibrate showed a significant reduction in heart rate and blood pressure in hypertriglyceridemic patients(3 Trusted Source
Bezafibrate reduces heart rate and blood pressure in patients with hypertriglyceridemia

Go to source
).

Q: Does Bezafibrate lower blood sugar?

A: Bezafibrate significantly reduces plasma glucose levels and used in the treatment of hyperglycemia(4 Trusted Source
Bezafibrate reduces blood glucose in type 2 diabetes mellitus

Go to source
).

Q: Does Bezafibrate cause muscle pain?

A: Bezafibrate, a hypolipidemic agent, may cause muscle pain and weakness, which is very rare(5 Trusted Source
Acute severe myositis due to bezafibrate treatment

Go to source
).

  • 1. Bezafibrate and simvastatin combination therapy for diabetic dyslipidaemia: efficacy and safety - (https://pubmed.ncbi.nlm.nih.gov/10809995/ )
  • 2. Bezafibrate may attenuate biliary damage associated with chronic liver diseases accompanied by high serum biliary enzyme levels - (https://pubmed.ncbi.nlm.nih.gov/16933007/ )
  • 3. Bezafibrate reduces heart rate and blood pressure in patients with hypertriglyceridemia - (https://pubmed.ncbi.nlm.nih.gov/11330878/ )
  • 4. Bezafibrate reduces blood glucose in type 2 diabetes mellitus - (https://pubmed.ncbi.nlm.nih.gov/10726910/ )
  • 5. Acute severe myositis due to bezafibrate treatment - (https://pubmed.ncbi.nlm.nih.gov/2722079/ )
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