Written & Compiled by Anushta Chandrapalan, M.Sc  | Medically Reviewed by The Medindia Medical Review Team
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General Information on Bevacizumab

Generic Name : Bevacizumab

Pronunciation : be va siz' yoo mab

Latest prescription information about Bevacizumab. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y43.3 | Therapeutic Classification : Chemotherapy

Trade Names/Brand Names of Bevacizumab

International- Avastin.

Why is Bevacizumab Prescribed? (Indications)

This medication is used to treat certain types of advanced lung cancer. It is also used to treat certain types of brain, breast, kidney, colon, or rectal cancer along with other cancer medicines. 

When should Bevacizumab not to be taken? (Contraindications)

Contraindicated in patients with hole in stomach or intestine, wound, and hypersensitivity.

What is the dosage of Bevacizumab?

Metastatic Carcinoma of the Colon or Rectum - Adults
IV infusion 5 or 10 mg/kg every 14 days in combination with IV 5-fluorouracil�based chemotherapy. The recommended dosage is 5 mg/kg every 14 days when administered with irinotecan/5-fluorouracil/leucovorin, and 10 mg/kg every 14 days when administered with 5-fluorouracil/leucovorin/oxaliplatin.

How should Bevacizumab be taken?

This medication available in the form of injection, administered by health care provider, intravenously. It is usually given once every 14 days to treat breast cancer or cancer of the colon or rectum and once every 3 weeks to treat lung cancer

What are the warnings and precautions for Bevacizumab?

• It may reduce the number of clot-forming cells (platelets) in your blood. Avoid injuries.

• Caution should be exercised in patients with history of cancer and heart disease, congestive heart failure, high blood pressure, during pregnancy and lactation.

What are the side effects of Bevacizumab?

  Gastrointestinal: Changes in taste, constipation, diarrhea, increased thirst, indigestion, loss of appetite, mouth pain or sores, nausea, vomiting, black, tarry stools and dry mouth.
  Central Nervous System: Dizziness, tiredness and headache.
  Skin: Dry skin, hair loss, swelling, or redness at the injection site, rash, hives, itching and swelling of the mouth, face, lips, or tongue.
  Eye and ENT: Nosebleed, stuffy or runny nose and voice changes.
  Heart: Difficulty breathing, tightness in the chest, congestive heart failure, calf pain or tenderness and chest pain.
  Miscellaneous: Muscle pain, sluggishness, weakness and weight loss.

What are the other precautions for Bevacizumab?

Do not administer or mix bevacizumab with dextrose solutions.

What are the storage conditions for Bevacizumab?

It is normally handled and stored by healthcare providers.

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