This medication is a diarylquinoline anti-tuberculosis drug, prescribed for multi-drug resistant tuberculosis (MDR-TB) with other medications.
PO- The recommended dose is 400 mg once daily for 2 weeks followed by 200 mg 3 times per week for 22 weeks.
It comes as a tablet to take by mouth, with food.
• Caution should be exercised in patients with history of abnormal heart rhythm, congenital long QT syndrome, other heart, liver or kidney problems, HIV infection, any allergy, who are taking other medications, during pregnancy and breastfeeding.
• Monitor ECGs frequently.
• Non-adherence to the treatment regimen could result in failure or resistance.
• Most Common: Nausea, joint pain, headache, coughing up of blood and chest pain.
Avoid excess dosage.
Store at 25°C.