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General Information on Apixaban

Generic Name : Apixaban

Latest prescription information about Apixaban. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.

Trade Names/Brand Names of Apixaban

International- Eliquis.

Why is Apixaban Prescribed? (Indications)

This medication is an anticoagulant, which is used for reducing the risk of strokes and blood clots in patients with atrial fibrillation who have no problems with their heart valve (nonvalvular atrial fibrillation).  

When should Apixaban not to be taken? (Contraindications)

Contraindicated in patients with active pathological bleeding and hypersensitivity. It should not be co-administered with unfractionated heparin (UFH), enoxaparin and dalteparin, fondaparinux, and oral anticoagulants.

What is the dosage of Apixaban?

PO- The recommended dose is 5 mg twice daily.
Decrease dose to 2.5 mg PO BID in following conditions
- while coadministrating strong dual inhibitors.
- age ≥ 80 years
- body weight ≤ 60 kg
- serum creatinine ≥ 1.5 mg/dL

How should Apixaban be taken?

It comes as a tablet to take by mouth, with or without food.

What are the warnings and precautions for Apixaban?

Caution should be exercised in patients with history of kidney or liver problems, bleeding problems, any allergy, who are taking other medications, children, during pregnancy and breastfeeding.

Patients already taking 2.5 mg BID, avoid coadministration with strong dual inhibitors.

Discontinuing eliquis in patients without adequate continuous anticoagulation increases risk of stroke.

What are the side effects of Apixaban?

The most common side effect is bleeding. Other side effects include bleeding in the stomach, intestines, brain, and eyes; the bleeding may be fatal.

What are the other precautions for Apixaban?

Avoid excess dosage.

What are the storage conditions for Apixaban?

Apixaban should be stored at room temperature between 15 C to 30 C (59 F to 86 F).

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