This medication is an antineoplastic agent, prescribed for malignant lymphoma and acute adult lymphoblastic leukemia. It is usually given in combination with other chemotherapy drugs.
IV- Adult: Induction: 90 mg/m2/day for 5-8 days, may increase to 120 mg/m2/day.
It comes as a red colored solution for injection to be administered by a healthcare provider into the vein.
• Caution should be exercised in patients with liver or kidney diseases, with low levels of potassium in their blood, who have already had treatment with other types of anticancer medications, during pregnancy and breastfeeding.
• Monitor complete blood counts, electrolyte for each treatment, heart, liver, kidney and CNS function regularly.
• Not to be used in people with a severe reduction in blood cell production by the bone marrow.
• This medicine is not recommended for children under 12 years old.
• Most Common :
Fatigue (tiredness), sore mouth and throat, loss of fertility, absence of menstrual period, decrease in the number of healthy white blood cells, red blood cells or platelets in the blood.
• Miscellaneous : Hair loss, abdominal pain, pain and swelling at injection site, nausea, vomiting, diarrhea, fever, infections, convulsions, disturbances in liver function, jaundice, acute kidney failure, blood in the urine, abnormal heart beats, heart failure or heart attack.
Avoid excess dosage.
Store the medication as directed by your physician.