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Amsacrine - Indications, Dosage, Side Effects and Precautions

Last Updated on August 11, 2022
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Information about Amsacrine

Generic Name : Amsacrine
Up-to-date prescription details regarding Amsacrine are provided here.
Understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.
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Trade Names/Brand Names of Amsacrine

International- Amsidine, m-AMSA, AMSA P-D , Amsidyl,Amsine, Amekrin, Lamasine.
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Why is Amsacrine Prescribed? (Indications)

This medication is an antineoplastic agent, prescribed for malignant lymphoma and acute adult lymphoblastic leukemia. It is usually given in combination with other chemotherapy drugs. 

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When should Amsacrine not be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Amsacrine?

IV- Adult: Induction: 90 mg/m2/day for 5-8 days, may increase to 120 mg/m2/day.

How should Amsacrine be taken?

It comes as a red colored solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Amsacrine?

• Caution should be exercised in patients with liver or kidney diseases, with low levels of potassium in their blood, who have already had treatment with other types of anticancer medications, during pregnancy and breastfeeding.

Monitor complete blood counts, electrolyte for each treatment, heart, liver, kidney and CNS function regularly.

Not to be used in people with a severe reduction in blood cell production by the bone marrow.

This medicine is not recommended for children under 12 years old.

What are the side effects of Amsacrine?

   Most Common : Fatigue (tiredness), sore mouth and throat, loss of fertility, absence of menstrual period, decrease in the number of healthy white blood cells, red blood cells or platelets in the blood.
   Miscellaneous : Hair loss, abdominal pain, pain and swelling at injection site, nausea, vomiting, diarrhea, fever, infections, convulsions, disturbances in liver function, jaundice, acute kidney failure, blood in the urine, abnormal heart beats, heart failure or heart attack.

What are the other precautions for Amsacrine?

Avoid excess dosage.

What are the storage conditions for Amsacrine?

Store the medication as directed by your physician.

Last Updated : August 11, 2022



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