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Last Updated : August 2013
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General Information on Amlodipine and Benazepril

Generic Name : Amlodipine and Benazepril

Pronunciation : am-LOE-di-peen/ben-AZ-e-pril

Latest prescription information about Amlodipine and Benazepril. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y52.4 | Therapeutic Classification : Anti- Hypertensives

Trade Names/Brand Names of Amlodipine and Benazepril

India- Amace- BP, Amlo-B.
International- Lotrel.

Why is Amlodipine and Benazepril Prescribed? (Indications)

This combination medication is used to treat high blood pressure (hypertension). Amlodipine belongs to a class of medications called calcium channel blockers. It works by relaxing the blood vessels so the heart does not have to pump hard. Benazepril is an angiotensin-converting enzyme (ACE) inhibitor. It works by decreasing certain chemicals that tighten the blood vessels, so blood flows more smoothly.  It widens blood vessels and improves blood flow.

When should Amlodipine and Benazepril not to be taken? (Contraindications)

Contraindicated in patients with history of severe kidney problems, angioedema. It should not be co-administered with angiotensin receptor blockers, ACE inhibitors in patients with diabetes.

What is the dosage of Amlodipine and Benazepril?

PO- The recommended dose is one capsule containing amlodipine 2.5-10 mg and benazepril 10-40 mg- once daily. Combination of amlodipine beslate and benazepril hydrochloride is available in the following strength 2.5/10 mg, 5/10 mg, 5/20 mg, 5/40 mg, 10/20 mg and 10/40 mg.

How should Amlodipine and Benazepril be taken?

It comes as a capsule to take by mouth, with or without food.

What are the warnings and precautions for Amlodipine and Benazepril?

Caution should be exercised in patients with history of heart problems, blood vessel problems, blood flow problems, bone marrow problems, kidney problems, kidney transplant, vascular disease, bone marrow suppression, low blood counts, narrowing or hardening of the arteries of the brain, dehydration, low blood volume, low blood pressure, diabetes, who are receiving kidney dialysis, elderly, children, during pregnancy and breastfeeding.

It may cause dizziness, lightheadedness, or fainting, do not drive a car or operate machinery while taking this medication.

Avoid alcohol consumption.

Monitor blood potassium levels, blood pressure, and kidney function regularly while taking this medication.

Inform your doctor if you are allergic to amlodipine (Norvasc), benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), trandolapril (Mavik), or any other medications.

What are the side effects of Amlodipine and Benazepril?

   Most Common : Cough, headache, dizziness, fluid retention.
   Body as a Whole : Swelling of the hands, feet, ankles or lower legs, fever, chills, flu symptoms, weakness, fatigue.
   Central Nervous System : Sleeplessness, nervousness, anxiety, tremor, and decreased libido.
   Skin : Flushing, hot flashes, rash, yellowing of the skin or eyes, skin nodule, and skin inflammation.
   Gastrointestinal : Dry mouth, nausea, abdominal pain, constipation, diarrhea, indigestion, and esophagitis.
   Blood : Decrease in white blood cells.
   Metabolic : Decrease in blood potassium, anemia and reduced number of platelets.
   Musculoskeletal : Back pain, muscle, joint pain, and muscle cramps.
   Respiratory : Throat inflammation.
   Genitourinary : Sexual problems such as impotence, and increased urination.

What are the other precautions for Amlodipine and Benazepril?

Avoid excess dosage.

What are the storage conditions for Amlodipine and Benazepril?

Store at 25C. Excursions permitted to 15-30C. Protect from moisture. Dispense in tight container.

Last Updated : August 2013
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