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General Information on Aminocaproic Acid

Generic Name : Aminocaproic Acid

Pronunciation : a- mee- noe- ka- proe'- ik- as- id

Latest prescription information about Aminocaproic Acid. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y44.2 | Therapeutic Classification : Anticoagulants / Antithrombotics

Trade Names/Brand Names of Aminocaproic Acid

India : 

International : 

Amicar

Why is Aminocaproic Acid Prescribed? (Indications)

This medication is an antidote, prescribed for excessive bleeding caused by fibrinolytic drugs. It may also be used in some other conditions to stop excessive bleeding e.g.abruptio placentae, bleeding after delivery etc.  

When should Aminocaproic Acid not to be taken? (Contraindications)

Bleeding due to disseminated intravascular coagulation. Rapid IV administration.

What is the dosage of Aminocaproic Acid?

PO- Treatment and prophylaxis of haemorrhage- Initial: 4-5 g, then 1-1.25 g hourly, usually up to 8 hour or until bleeding has been controlled. Max: 30g/24 hour.
Patients with haemophilia undergoing dental extraction- Initial: 6 g immediately after extraction, then 6 g 6 hourly for up to 10 days.
IV- Treatment and prophylaxis of haemorrhage- As 2% solution: Initial: 4-5 g over 1 hour, then continuous infusion of 1 g/hour for usually up to 8 hour or until bleeding is controlled. Max: 24 g/24 hour

How should Aminocaproic Acid be taken?

It is available as a tablet, syrup and an injection.

What are the warnings and precautions for Aminocaproic Acid?

Caution should be exercised in patients with history of urinary tract bleeding, skeletal muscle disease, neonates, veno-occlusive hepatic disease (small veins in liver are blocked)or kidney disease.

Monitor creatinine phosphokinase level regularly.

Avoid administration with factor IX complex concentrates and during pregnancy and lactation.

What are the side effects of Aminocaproic Acid?

  Heart: Slow heart rate, low blood pressure, peripheral ischemia and thrombosis.
  Central Nervous System: Dizziness, headache, delirium, hallucinations, confusion, intracranial hypertension, stroke and loss of consciousness.
  Skin: Rash and itching.
  Eye and ENT: Ringing in the ear, decreased vision and watery eyes.
  Gastrointestinal: Nausea, diarrhea, abdominal pain and vomiting.
  Genitourinary: Bladder obstruction due to clot, increased blood, urea, nitrogen and renal failure.
  Blood: Decrease in white blood cells, thrombocytes and coagulation disorder.
  Respiratory: Difficulty breathing or shortness of breath, nasal congestion and blood clot in lungs.
  Miscellaneous: Injection site reaction, pain and necrosis, muscle pain, inflammation of your skeletal muscle, myopathy , edema,allergic and anaphylactic reactions and uneasiness.

What are the other precautions for Aminocaproic Acid?

Avoid sudden position changes to prevent low pressure.

What are the storage conditions for Aminocaproic Acid?

Injection: Store at 15-30�C. Store it in airtight container and keep away from children.

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