This medication is an aminoglycoside antibiotic, prescribed for serious bacterial infections. It inhibits the production of bacterial proteins, which causes bacterial cell death.
Generally not indicated for long-term therapy because of ototoxicity (damage to the ear) and nephrotoxicity (damage to kidney cells).
The recommended dose is 15mg/kg/day in 1-3 doses, urinary tract infection 250mg twice a day.
This medication available in the form of injection, administered by a healthcare professional.
Caution should be exercised in patients with history of kidney disease, vertigo, hearing loss, ringing in the ears, myasthenia gravis, or Parkinson's disease, during pregnancy.
Discontinue, if signs of ototoxicity, neurotoxicity or hypersensitivity occurs; and during lactation.
Safety has not been established for treatment period >14 days.
Monitor renal function before and during treatment.
Muscle weakness (due to blocking of signals from the nerves to the muscles).
Eye and ENT: Hearing loss and loss of balance.
Genitourinary: Reduced urine volume, protein in urine, increased serum creatinine, urinary casts, red and white blood cells in urine and high level of nitrogen waste in blood (azotemia).
Miscellaneous: Decreased serum magnesium.
Do not change the dose without consulting your doctor.
Injection: Store it in the refrigerator or freezer. Take your next dose from the refrigerator 1 hour before using it; place it in a clean, dry area to allow it to warm to room temperature. Do not refreeze medications.
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