Pallavi Singh
Written & Compiled by Pharmacist Pallavi Singh, M. Pharmacy (Pharmacy Practice)
Dr. Simi Paknikar
Medically Reviewed by Dr. Simi Paknikar, MD
Last Updated on May 02, 2018
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General Information on Adenosylcobalamin

Generic Name : Adenosylcobalamin

Pronunciation :  a-deno-syl-ko-bala-min

Latest prescription information about Adenosylcobalamin. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the Indian trade name(s) of the drug and its price list.
Therapeutic Classification : Vitamins

Trade Names/Brand Names of Adenosylcobalamin

Why is Adenosylcobalamin Prescribed? (Indications)

Adenosylcobalamin is an active form of vitamin B12, a water-soluble vitamin used as a nutritional supplement to treat vitamin B12 deficiency or pernicious anemia, stomatitis, as well as for other conditions like depression, panic attacks and anxiety. Adenosylcobalamin is also known as cobamide or dibencozide.  

When should Adenosylcobalamin not to be taken? (Contraindications)

• Allergic to adenosylcobalamin .

What is the dosage of Adenosylcobalamin?

• The recommended dose for adenosylcobalamin varies depending on the patient’s physiological condition and whether it is used for preventive purpose or for treatment of vitamin B12 deficiency.

How should Adenosylcobalamin be taken?

• Adenosylcobalamin should be taken orally before or after food intake.
• It is usually available as a combination with other supplements.
• Lozenges or sublingual tablets should be allowed to dissolve in the mouth.

What are the warnings and precautions for Adenosylcobalamin?

• Patients with intestinal disorders, vitamin B12 malabsorption syndrome, and surgical removal of intestinal organs may not be able to absorb adenosylcobalamin.
• Blood tests may be advised before and after a few months of treatment to document a good response to treatment.

What are the side effects of Adenosylcobalamin?

• The side-effects of adenosylcobalamin may include the following:

•  General: Fever, low blood potassium levels
•  Allergic reaction: Rash, itching, swelling under the skin, possible anaphylactic shock
•  Digestive tract: Mild transient diarrhea, nausea, vomiting
•  Nervous system: Tingling and numbness, headache, dizziness
•  Blood: Polycythemia vera (increased production of red blood cells by the bone marrow)
•  Heart: Congestive heart failure, low blood pressure, fluid accumulation in the lungs
•  Eyes: Vision problems

What are the other precautions for Adenosylcobalamin?

Inform your doctor in the following situations:

• Impaired kidney or liver function
• Iron and folic acid deficiency along with vitamin B1 deficiency
• Leber’s disease
• Pregnant and breastfeeding women

What are the Drug Interactions of Adenosylcobalamin?

Adenosylcobalamin may interact with

• Chloramphenicol
• Methotrexate
• Pyrimethamine
• Cholestyramine
• Colchicine
• Heavy alcohol intake

What are the storage conditions for Adenosylcobalamin?

• Adenosylcobalamin should be stored as advised by the labelling.
• Protect from excess heat and light.
• Keep out of reach of children.

Last Updated : July 2018

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