Hematology Test

LE cell Test/ Lupus Test

Dr. Simi Paknikar
Medically Reviewed by Dr. Simi Paknikar, MD
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Test : LE cell Test/ Lupus Test

Indications : Evaluate autoimmune diseases, Systemic Lupus erythrematous and in the diagnosis of “lupoid” hepatitis (Chronic active hepatitis).

Physiology : SLE is a disease of protean clinical manifestations commonly with rash, arthralagia, fever, anemia, leukopenia, thrombocytopenia, and hypocomplementemia. The patient’s serum should be studied for antinuclear antibody (ANA). The antibody may be IgG, IgA, or IgM specificity but is most commonly of IgG class.

Normal Range : Negative.

Test Method : Blood cells are ruptured and nuclear material is released, which interacts with specific antibody by phagocytosis.

Related Tests : Anti-DNA, Antinuclear Antibody, Scleroderma Antibody, Sjogren’s Antibodies, Smooth Muscle Antibody

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