Hematology Test

Glucose –6- Phosphate Dehydrogenase, Quantitative/ G-6-PD

Dr. Simi Paknikar
Medically Reviewed by Dr. Simi Paknikar, MD
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Test : Glucose –6- Phosphate Dehydrogenase, Quantitative/ G-6-PD

Indications : This test is to evaluate G-6-PD deficiency, determine the cause of drug induced hemolysis or hemolysis secondary to acute bacterial or viral infections or metabolic disorders such as acidosis. Mutations responsible for the G-6-PD deficient state can be identified by use of molecular biologic techniques

Physiology : G-6-PD hemolysis is associated with formation of Heinz bodies in peripheral RBC’s. Quantitative G-6-PD is helpful in establishing diagnosis of mild G-6-PD deficiency who have had recent hemolysis.

Normal Range : 8.34 ± 1.59 IU/g hemoglobin

Test Method : Measure the formation of NADPH following change in absorbance at 340 nm at 370C.

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