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How does V. cholera causes Pathogenicity

V. cholerae is pathogenic only for humans

Cholera Vibrios are ingested in drink or food and in natural infections, the small dose is enough to cause an infection. After passing the acid barrier of the stomach
the organisms begin to multiply in the alkaline environment of the small intestine.

It gets attached to the microvilli of the epithelial cells of the intestinal tract where it multiplies and produce a potent enterotoxin known as cholera toxin.

Cholera toxin is responsible for increased secretion of water and electrolytes in stools from the intestinal cells leading to dehydration, shock, acidosis and death.

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Grace is mean to me all the time!!!
kelli.7 Wednesday, May 12, 2010
In Zimbabwe the National Water Authority is failing to supply water to large parts of the urban areas. This has resulted in residences drawing on Boerhole Water and others purchasing from borehole owners. My question is what is the risk of being infected by the Cholera Bacteria especially in schools who use the water to wash with but not to drink?
Gavin Tuesday, November 18, 2008

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