About Vitamin B-12
The central structure of the vitamin consists of a single cobalt atom surrounded by four pyrrole rings. This set up is called 'Corrin Ring' system. This cobalt atom is in turn covalently bounded to a cyanide group. It is hence called cyanocobalamine.
Vitamin B-12 is required for the conversion of homocysteine to methionine which is processed by enzymes. Vitamin B12 deficiency, like folic acid deficiency, can cause increased homocysteine in the blood.
Vitamin B-12 and folate are both necessary for the synthesis of raw materials that make up the DNA.
Latest Publications and Research on Vitamin B-12[State of thiol exchange in patients with psoriasis and its possible correction]. - Published by PubMed
Dietary Supplement Use and Smoking Are Important Correlates of Biomarkers of Water-Soluble Vitamin Status after Adjusting for Sociodemographic and Lifestyle Variables in a Representative Sample of U.S. Adults. - Published by PubMed
DNA methylation potential: dietary intake and blood concentrations of one-carbon metabolites and cofactors in rural African women. - Published by PubMed
Genetic Variants Influencing Biomarkers of Nutrition Are Not Associated with Cognitive Capability in Middle-Aged and Older Adults. - Published by PubMed
Evaluation of cyanocobalamin in multivitamin tablets and their Standard Reference Material 3280 by HPLC with visible detection. - Published by PubMed