The end result of a rhythm disorder is sleep deprivation.
Death and Circadian Rhythm Sleep Disorders: Many deaths related to circadian rhythm disorders are the result of impaired performance secondary to sleep deprivation; therefore, many times, the deaths are categorized into different headings (eg, motor vehicle accidents, heavy machinery accidents, other accidents). Sometimes, the deaths are squeal to the use of hypnotics and/or alcohol to treat insomnia.
Health risks associated with Circadian Rhythm Sleep Disorders: 
Shift workers have been found to have a 40% greater cardiovascular disease risk than non-shift workers. Frequency of gastrointestinal symptoms, other psychosomatic symptoms, and psychiatric symptoms also is increased in shift workers.

Daytime sleepiness in students with DCR disorder has been correlated with negative mood and increased smoking and alcohol consumption.
Some of the features of depressive disorders, such as early morning awakening and decreased rapid eye movement (REM) latency, are suggestive of ACR disorder. Whether these changes are secondary to depression or actually cause it has not been established.