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| Disease Info Index | ||||||||||||||||||||||||||
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Narcolepsy
Drugs For Narcolepsy
armodafinil
dextroamphetamine
imipramine
methamphetamine
methylphenidate
modafinil
pemoline
sodium oxybate
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Sleep Disorder: Narcolepsy | |
Overview |
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Narcolepsy is a neurological sleep disorder in which the individual has an uncontrollable desire to fall asleep. Narcolepsy patients sleep as much as a normal person, the only difference is they are powerless to control their sleep timings. Recent research indicates that narcolepsy may be caused by the deficient production of a chemical called 'hypocretin' in the brain. These sleep attacks occur as brief episodes and may take place even in the most stimulating circumstances, like while driving or talking to a person. Research has shown that narcoleptics are more accident-prone and may also have some difficulty with interpersonal relationships.
 Cataplexy Dreams Sleep paralysisIt is estimated to be the second leading cause for daytime sleepiness after obstructive sleep apnea. Narcolepsy-cataplexy was first reported by Westphal (1877) and Fisher (1878). They showed the association of muscle weakness triggered by excitement and sleepiness. The original description of the condition reads as follows: In the case of narcoleptic individuals the brain is not able to regulate the smooth transition of the sleep wake cycles, resulting in the patients directly entering REM sleep without experiencing NREM sleep. Researchers have discovered abnormalities in parts of the brain involved in regulating REM sleep.The majority of narcoleptic patients are still undiagnosed, and diagnosis often occurs after many years of struggle. One recent study estimated the mean number of years between the onset of symptoms and the correct diagnosis to be 14 years. As the symptoms of narcolepsy usually appear during adolescence, most narcoleptic patients are diagnosed too late to prevent the impact of the disease on their personal and professional development. 
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Latest Publication and Research on Narcolepsy - Updated on 12/06/2011
A remarkable effect of alemtuzumab in a patient suffering from narcolepsy with cataplexy. - Published by PubMed
A remarkable effect of alemtuzumab in a patient suffering from narcolepsy with cataplexy. - Published by PubMed
Quality of life in patients with narcolepsy with cataplexy, narcolepsy without cataplexy, and idiopathic hypersomnia without long sleep time: Comparison between patients on psychostimulants, drug-naďve patients and the general Japanese population. - Published by PubMed
[Hypothalamic involvement in multiple sclerosis.] - Published by PubMed
Activation of central orexin/hypocretin neurons by dietary amino acids. - Published by PubMed
A remarkable effect of alemtuzumab in a patient suffering from narcolepsy with cataplexy. - Published by PubMed
A remarkable effect of alemtuzumab in a patient suffering from narcolepsy with cataplexy. - Published by PubMed
Quality of life in patients with narcolepsy with cataplexy, narcolepsy without cataplexy, and idiopathic hypersomnia without long sleep time: Comparison between patients on psychostimulants, drug-naďve patients and the general Japanese population. - Published by PubMed
[Hypothalamic involvement in multiple sclerosis.] - Published by PubMed
Activation of central orexin/hypocretin neurons by dietary amino acids. - Published by PubMed
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Posted by:
1a2b3c(Guest)
Posted on: 03/09/2011 I heard this condition might be linked to the H1N1 vaccine, we believe my 12 year old daughter has it and it was right after she had the vaccine.
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