Silicosis is a term was introduced by Visconti in 1870 and was derived from Latin silex, or flint. Chronic silicosis initially causes no symptoms or old mild respiratory difficulties. Over years it may, however progress to involve most of the lung.
All patients are at about 30-fold increased risk of pulmonary TB or nontubercular mycobacterial disease. Exposure to silica (without developing silicosis) alone can triple the risk. Chronic silicosis initially causes no symptoms or old mild respiratory difficulties. Over years it may, however progress to involve most of the lung and may cause dyspnoea (difficulty to breathe) at rest. Patients with silicosis will gave an occupational history of silica exposure
Diagnosis is based on history and radiological findings. A diagnosis of silicosis is usually confirmed by chest x-ray or CT appearance. CT is more sensitive than x-ray.
Treatment is chiefly supportive. There is no specific therapy that can cure or alter the course of silicosis. The first step in the treatment of silicosis is to prevent further exposure to silica dust. Patients must quit smoking. Immunization against influenza and pneumococcal pneumonia is advised. Patients with acute silicosis may benefit from corticosteroids. Severe cases may require lung transplantation. Introduction of mechanized mining brought about an increase in prevalence of silicosis. No racial predilection is reported. Male workers are primarily affected. Not much information regarding age is available. The general term for lung disease caused by inhalation of mineral dust is pneumoconiosis.
Latest Publications and Research on SilicosisThe correlation of SUVmax with pathological characteristics of primary tumor and the value of Tumor/ Lymph node SUVmax ratio for predicting metastasis to lymph nodes in resected NSCLC patients. - Published by PubMed
Pulmonary tuberculoma and miliary tuberculosis in silicosis. - Published by PubMed
Increased risk of tuberculosis in patients with end-stage renal disease: a population-based cohort study in Taiwan, a country of high incidence of end-stage renal disease. - Published by PubMed
[Diagnosis of pulmonary tuberculosis using Ziehl-Neelsen stain and polymerase chain reaction.] - Published by PubMed
[Hemoptysis in a patient with severe COPD and silicosis.] - Published by PubMed