Salivary glands are the organs that make saliva and release it into the mouth. Enzymes present in saliva help digest food. The secretion is also rich with antibodies that help protect against infections of the mouth and throat. The salivary glands are classified as major and minor.
The three pairs of major salivary glands are Parotid glands, Sublingual glands and Submandibular glands.
Parotid glands are the largest among these and are found in front of and just below each ear. Sublingual glands are found under the tongue in the floor of the mouth. Submandibular glands are found below the jawbone. Apart from the three pairs of major salivary glands there are hundreds of small (minor) salivary glands.
Symptom & Signs: Most salivary gland tumors are not dangerous to health (i.e. benign) and occur in the parotid glands. The most common sign of a salivary gland tumour is a painless salivary mass or a newly noticed lump on the side of the face or below the jawbone. . Sometimes there maybe difficulty in swallowing
Diagnosis: It is evaluated by a technique called fine-needle aspiration biopsy. CT scans and MRI usually aid in detailed workup.
Treatment: Malignant tumours that pose danger to health usually need surgical excision and radiation.
Prognosis: This depends upon the grade of the cancer. Higher grade have a poorer outcome.
Latest Publications and Research on Salivary Gland CancerDetailed Genome-Wide SNP Analysis of Major Salivary Carcinomas Localizes Subtype-Specific Chromosome Sites and Oncogenes of Potential Clinical Significance. - Published by PubMed
Radiotherapy for nonadenoid cystic carcinomas of major salivary glands. - Published by PubMed
A rare cutaneous presentation of metastatic parotid adenocarcinoma. - Published by PubMed
Contemporary evaluation and management of parapharyngeal space neoplasms. - Published by PubMed
Dose-response analysis of parotid gland function: What is the best measure of xerostomia? - Published by PubMed