Rickets / Paediatric Osteomalacia

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What are the causes of rickets?

The main cause of rickets is the deficiency of vitamin D caused in the body during childhood. Vitamin D is a fat-soluble vitamin that may be absorbed from the intestines or may be produced by the skin when the skin is exposed to sunlight (ultraviolet light of sunlight helps the body to form vitamin D). The absorbed vitamin D is converted into its active form to act as a hormone to regulate calcium absorption from the intestine and to regulate levels of calcium and phosphate in the bones. If there is a deficiency of Vitamin D, the body is unable to properly regulate calcium and phosphate levels. When the blood levels of these minerals become too low, it results in destruction of the support matrix of the bones.


In rickets, another mechanism in the body works to increase the blood calcium level. The parathyroid gland (four numbers of hormone producing glands, usually located in the neck) may increase its functioning rate to compensate for decreased levels of calcium in the bloodstream.To increase the level of calcium in the blood the hormone destroys the calcium present in the bones of the body and this results in further loss of calcium and phosphorous from the bones. In severe cases, cysts may develop in the bones. Vitamin D deficiency could be caused due to numerous reasons.

Bullet Environmental conditions where sunlight exposure is limited like indoor confinement or working indoors during daylight hours may reduce source of vitamin D.

Bullet A lack of vitamin D in the diet.

Bullet Problem of malabsorption called steatorrhea, in which the body is unable to absorb fats, and they are passed directly out the body in the stool. The result of this problem is that Vitamin D, which is usually absorbed with fat, and calcium are poorly absorbed. This poor absorption can be a result of digestive disorders. Steatorrhea could also lead to other deficiencies.

Bullet Due to tubular acidosis in which there is an increased amount of acid in the body fluids as a result of congenital or acquired kidney disorders.

Bullet A dietary lack of calcium and phosphorous may also play a part in nutritional causes of rickets.

Bullet A dietary lack of vitamin D may occasionally occur in people on a vegetarian diet who do not drink milk products or in people who are lactose intolerant (have trouble digesting milk products).

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kasadiekay Tuesday, February 25, 2014

Hey everyone! I am 19 years old and I was born with Rickets. I couldn't walk but I could only crawl backwards. so my mom took me to several hospitals to figure out was wrong with her baby girl. no doctor could ever find out what was wrong with me. Then someone told my mom about the Shriners Hospital which has a bone center in Shreveport Louisiana. They are the best hospital I have ever been to! I have had a mickey-G-tube in my stomach for vitamins, tubes up my nose, I used to have to take shots every day to help me grow, and also 5 surgeries on my legs to help straight my bowed legs out. They would always bow again and come out negative but when I was in the seventh grade I had my last final surgery to straight my legs and ever since then I am doing great! Shriners Hospital is an amazing hospital and I would advise any young child to go there for help they inspired me and made me want to go to college to become a nurse and work there one day to help kids in need just like they help me.

Rickets Saturday, July 20, 2013

Please help me i am a poor man and i have rickets problem please help me.

shadmah Sunday, July 8, 2012

please may i know the differential diagnosis of rickets

vanna21 Sunday, January 15, 2012

hiii im a 21 year old female I have Hypophosphatemic rickets I have never had any operations im trying to see how to go about doing so any tipss??

cif12 Wednesday, May 9, 2012

Do you have deformities?

jennacismowski Thursday, September 13, 2012

I am 22 years old [girl] with hypophosphatemia, i had a surgery when i was 14 years old to close the growth plates in my knees to stop any more bowing in my legs. if you live close, at all, to California, UCSF is awesome. i am currently in a study for a new drug for treatment of this disease and so far, the drug has been helping me a lot. i still have a lot of bone pain and joint pains, but it does seem to be helping.

nee_naw95 Thursday, October 24, 2013

Hey I am an 18 year old female and I am in the same situation. I have currently been getting more sharper pains my legs and find it really difficult to walk. Although I don't know whether to get the operation if it is just for cosmetic reasons.

Sana17 Sunday, June 5, 2011

i am 17 turning 18 this year, i had an operation last august on my left leg due to rickets and had metal plates placed in, this august i am having surgery again so that they can take the metal out, and then the same procedure is taking place on my right leg and then next summer theyre taking the metal plate out on right leg, they adjusted the alignment, i didnt realise alot of people have rickets until i saw this

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