Become a member
Quick Registration
Full Registration Benefits -
Free Homepages for Doctors
Free Homepages for Hospitals
Free Homepages for Medical Conference
Free Homepages for NGO's
Personal Health Record Creation
Access to all Medical Slides
Access to all Jobs & Products Sale
| Disease Info Index | ||||||||||||||||||||||||||
|
|
Organophosphorus Poisoning
Drugs For Organophosphorus Poisoning
Page Options
Organophosphorus Poisoning
3.79
/5
Comments : 2
| |||
About |
|||
Text 
|
Organosphosphorus compounds are used as insecticides and chemical warfare. They are easily accessible, thus they are a commonly associated with suicides and accidental poisoning. Organophosphorus compounds or organophosphates are commonly used in the industrial, agricultural and home settings. They were initially developed as insecticides but some of them i.e. sarin, soman, tabun and VX have been developed as “nerve gases”. These are used as chemical warfare and in terrorist attacks. Some organophosphorus compounds are used as pesticides in agriculture. These are highly toxic and include tetraethyl pyrophosphate and parathione. Other organophosphates such as coumaphos, chlorpyrifos and trichlorfon are used as animal insecticides and have intermediate toxicity. Low toxicity compounds are malathione, diazinon and dichlorovos. These are used as household insecticides.  Organophosphorus compounds are easily accessible and are often used to commit suicides. Accidental poisoning may also occur especially when they are kept within the reach of children. Farmers could get exposed while spraying crops if they are not well protected with masks, gloves and other protective clothing.
The nervous system is made up of a large number of nerves. When a signal reaches the end of a nerve, it releases a substance called neurotransmitter that carries the signal to the adjacent nerves or organ such as muscle or gland. Many nerves release acetylcholine as the neurotransmitter. Once the signal passes to the next nerve, an enzyme called choline esterase destroys the acetlycholine. Organophosphorus compounds block this enzyme, thus preventing the breakdown of acetylcholine. Thus acetlycholine acts for an excessively long time causing symptoms like twitches and increased secretions. After some time, the muscles gets fatigued leading to paralysis. Organophosphorus poisoning is treated using drugs that block the action of acetylcholine i.e. atropine and drugs that regenerate the cholinesterase enzyme i.e. pralidoxime and obidoxime. Diazepam is used to control seizures caused due to the poisoning. |
Latest Publication and Research on Organophosphorus Poisoning - Updated on 04/18/2013.
Mitochondrial dysfunction and organophosphorus compounds. - Published by PubMed
Study of poisoning cases in a tertiary care hospital. - Published by PubMed
Protein tyrosine adduct in humans self-poisoned by chlorpyrifos. - Published by PubMed
Is there a role for progesterone in the management of acute organophosphate poisoning during pregnancy? - Published by PubMed
"Toxic Pancreatitis with an Intra-Abdominal Abscess which was Caused by Organophosphate Poisoning (OP)". - Published by PubMed
Mitochondrial dysfunction and organophosphorus compounds. - Published by PubMed
Study of poisoning cases in a tertiary care hospital. - Published by PubMed
Protein tyrosine adduct in humans self-poisoned by chlorpyrifos. - Published by PubMed
Is there a role for progesterone in the management of acute organophosphate poisoning during pregnancy? - Published by PubMed
"Toxic Pancreatitis with an Intra-Abdominal Abscess which was Caused by Organophosphate Poisoning (OP)". - Published by PubMed
|
|
|
| Share it! |  |
 |
 |
 |
 |
 |
 |
Related Links
Lead poisoning in children
Toys and parks are no longer safe for children. It is the main cause for lead ...
Anthrax
Anthrax is caused by the bacterium Bacillus anthracis and spreads when the anthrax spores are inhaled, ingested, or come into contact with the skin ...
Bioterrorism-an interactive analysis - Animation
Interactive section of Medindia gives general the analysed information about ...
Must Know Facts On Poisoning
Important and interesting facts on poisoning - an avoidable public health problem that can happen to anyone, anytime or at any ...
Poisoning - First Aid and Emergency Treatment Guide
A quick and simple First Aid guide on how to administer treatment for ...
Health Acts in India - Insecticides Act, 1968
An Act to regulate the import, manufacture, sale, transport, distribution and use of insecticides with a view to prevent risk to human beings or ...
Organic Foods
Organic Foods are produced by the 'natural method', without the use of chemicals like pesticides, fertilizers or sewage ...
Environmental Birth Defects
Birth defects caused due to environmental teratogens like drugs, microorganisms or exposure to radiation are called as environmental birth ...
Suicide
Suicide is an act of ending one's own life and it usually results from emotional isolations and inability to adjust and cope with one's ...
Suicide Prevention-A Pro-Life Interview
A life is thrown away every 40 seconds somewhere in the world—by hanging oneself, slashing one's wrists, consuming an overdose of sleeping pills or ...
The Falling Sperm Count In Men
Over the last century the male sperm count has been gradually falling. Nobody knows the reason. Today the numbers of infertile men are much higher ...
Comment & Contribute
|
Posted by:
susanna123(Guest)
Posted on: 01/05/2013 We live in Pemba, Mozambique and prayed our yard today with Organophosphorus for the killing and prevention of ticks and fleas. The person of the company that did the spraying gave us a half liter of this mixture and said we can use this mixture on our dogs by applying a little bit with a paint brush directly on their skin. I want to confirm if I can use it as told to me by this person. Please let me know.
Thanks
Susan Venter
Reply |
Forward
|
