Microscopic Polyangiitis is treated using cyclophosphamide and a corticosteroid.
The following treatments are used for MPA: MPA is treated using a corticosteroid
(a drug that suppresses inflammation and immunity) and cyclophosphamide
(an anticancer drug that suppresses immunity). The patient could undergo complete cure or may experience relapses during treatment.
Other drugs that may be useful are methotrexate, azathioprine, cyclosporine, intravenous immunoglobulin and monoclonal antibodies.
Plasmapheresis (a procedure where antibodies are removed from the blood) may be useful in severe cases.
Trimethoprim – sulfamethoxazole, an antibiotic, may be used to prevent Pneumocystis carinii pneumonia in MPA patients.