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Thalassemia

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Latest Publication and Research on Thalassemia

Hepat Mon    

Patient-to-Patient Transmission of Hepatitis C at Iranian Thalassemia Centers Shown by Genetic Characterization of Viral Strains.

Samimi-Rad K, Asgari F, Nasiritoosi M, Esteghamati A, Azarkeyvan A, Eslami SM, Zamani F, Magnius L, Alavian SM, Norder H

Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, IR Iran.

Hepatitis C is prevalent among thalassemia patients in Iran. It is mainly transfusion mediated, in particular among patients treated before 1996 when ... Read More

Source: PubMed

Haematologica  2013 Apr 12  

Sildenafil therapy in thalassemia patients with doppler-defined risk for pulmonary hypertension.

Morris CR, Kim HY, Wood JC, Porter JB, Klings ES, Trachtenberg FL, Sweeters N, Olivieri NF, Kwiatkowski JL, Virzi L, Singer ST, Taher A, Neufeld EJ, Thompson AA, Sachdev V, Larkin S, Suh JH, Kuypers FA, Vichinsky EP

Emory-Childrens Center for Developmental Lung Biology, USA;

Pulmonary hypertension is a common but often overlooked complication associated with thalassemia syndromes. There is limited data on the safety and ef... Read More

Source: PubMed

Eur. J. Haematol.  2013 Apr 13  

Effect of splenectomy on iron balance in patients with ▀- Thalassaemia Major: a long term follow up.

Casale M, Cinque P, Ricchi P, Costantini S, Spasiano A, Prossomariti L, Minelli S, Frega V, Filosa A

UOD Microcitemia.

OBJECTIVE: A retrospective study was performed to explore the effect of splenectomy on iron balance in thalassaemia major (TM). METHODS: 22 TM patient... Read More

Source: PubMed

Hemoglobin  2013 Apr 12  

Evaluation and Comparison of Soluble Transferrin Receptor in Thalassemia Carriers and Iron Deficient Patients.

Khatami S, Dehnabeh SR, Mostafavi E, Kamalzadeh N, Yaghmaei P, Saeedi P, Shariat F, Bagheriyan H, Zeinali S, Akbari MT

Department of Biochemistry, Pasteur Institute of Iran , Tehran , Iran.

Iron is an essential component in the structure of certain molecules such as hemoglobin (Hb), myoglobin, cytochrome C and some enzymes. The iron gatew... Read More

Source: PubMed

Indian J Med Paediatr Oncol    

Stem cell transplant: An experience from eastern India.

Mukhopadhyay A, Gupta P, Basak J, Chakraborty A, Bhattacharyya D, Mukhopadhyay S, Roy UK

Department of Haemato-Oncology, Molecular Biology and Bone Marrow Transplant Unit, Netaji Subhas Chandra Bose Cancer Research Institute, Kolkata, West Bengal, India.

Hematopoietic stem cell transplant using human leukocyte antigen (HLA)-matched sibling or unrelated bone marrow, or related or unrelated cord blood ha... Read More

Source: PubMed

Hemoglobin  2013 Apr 11  

Application of Multiplex Ligation-Dependent Probe Amplification to Screen for ▀-Globin Cluster Deletions: Detection of Two Novel Deletions in a Multi Ethnic Population.

Cui J, Azimi M, Baysdorfer C, Vichinsky EP, Hoppe CC

Hemoglobinopathy Reference Laboratory, Children's Hospital & Research Center Oakland , Oakland, California , USA.

Hereditary persistence of fetal hemoglobin (HPFH) and d▀-thalassemia (d▀-thal) are heterogeneous disorders caused by deletions within the ▀-globin gen... Read More

Source: PubMed

ISRN Hematol    

Hemoglobin A2 Lowered by Iron Deficiency and a -Thalassemia: Should Screening Recommendation for ▀ -Thalassemia Change?

Denic S, Agarwal MM, Al Dabbagh B, El Essa A, Takala M, Showqi S, Yassin J

Department of Medicine, College of Medicine and Health Sciences, United Arab Emirates University, P.O. Box 17666, Al Ain, Abu Dhabi, UAE.

Screening for ▀ -thalassemia trait (BTT) relies on measuring hemoglobin (Hb) A2. Since multiple factors can affect HbA2 levels, the screening can beco... Read More

Source: PubMed

ScientificWorldJournal    

The impact of migrations on the health services for rare diseases in europe: the example of haemoglobin disorders.

Angastiniotis M, Vives Corrons JL, Soteriades ES, Eleftheriou A

Thalassaemia International Federation (TIF), 31 Ifigeneias Street, 2007 Strovolos, Nicosia, Cyprus ; European Network for Rare and Congenital Anaemias (ENERCA), 08036 Barcelona, Spain.

Migration from different parts of the world to several European countries leads to the introduction of haemoglobinopathy genes into the population, wh... Read More

Source: PubMed

Eur. J. Hum. Genet.  2013 Apr 10  

Next generation sequencing of SNPs for non-invasive prenatal diagnosis: challenges and feasibility as illustrated by an application to ▀-thalassaemia.

Papasavva T, van Ijcken WF, Kockx CE, van den Hout MC, Kountouris P, Kythreotis L, Kalogirou E, Grosveld FG, Kleanthous M

Molecular Genetics Thalassemia Department, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.

▀-Thalassaemia is one of the most common autosomal recessive single-gene disorder worldwide, with a carrier frequency of 12% in Cyprus. Prenatal tests... Read More

Source: PubMed

Patient Prefer Adherence    

Changes in the quality of life of people with thalassemia major between 2001 and 2009.

Gollo G, Savioli G, Balocco M, Venturino C, Boeri E, Costantini M, Forni GL

Regional Palliative Care Network, IRCCS AOU San Martino-IST, Genoa.

The prolonged survival of patients with thalassemia major as a result of the novel therapeutic strategies introduced in the last decade makes patient ... Read More

Source: PubMed

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jatin.sejpal Monday, January 31, 2011
salam
dear dr sahib
to day i saw your website on internet and i am very impress that u trying to treat thalassemia. i have a problumb that i want to tell you i have 9mounth baby he hase thalassemia Major we tried alot to treat him but invain becouse we also tried for Bone marrow transplant but his brother and sister bothe result wer matchless now we want to know abt any other treatment which serve our child in this case we need ur help if u have any treatment or know abt any perfect treatment please inform us i will be waiting for your reply .

Fragrance_of_flower Sunday, August 29, 2010
what is difference between bonemarrow & Cord blood stem cell transplantation? Which is the successful method or the estimated successful percentage for this? I thank Dr. Revathi Raj for hard work for his big acheivement. I am a father of 2+ Thalasemic boy.
Ibrahim-liyam Friday, September 18, 2009
Dr.Reavathy Raj is a great expert in the field of Hematology. She tailors treatments that will best suit the individual patients. She is Great.
ThankfulMom Friday, November 25, 2011

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