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Latest Publication and Research on Schizophrenia

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  2011 Dec 5  

Nicotine Reduces Antipsychotic-Induced Orofacial Dyskinesia in Rats.

Bordia T, McIntosh JM, Quik M

1 SRI International;

Antipsychotics are an important class of drugs for the management of schizophrenia and other psychotic disorders. They act by blocking dopamine recept... Read More

Source: PubMed

  2011 Dec 6  

Differences Between Victims of Bullying and Non-victims on Levels of Paranoid Ideation and Persecutory Symptoms, the Presence of Aggressive Traits, the Display of Social Anxiety and the Recall of Childhood Abuse Experiences in a Portuguese Mixed Clinical Sample.

Lopes BC

Faculdade de Psicologia e de Ciências da Educação, Universidade de Coimbra, Coimbra, Portugal. barbaracslopes@gmail.com.

BACKGROUND: Bullying has been considered as a traumatic experience that can lead to paranoid ideation in students (Campbell and Morrison, 2007). This ... Read More

Source: PubMed

  2011 Dec 5  

Who's left? Symptoms of schizophrenia that predict clinical trial dropout.

Thompson J, Berk M, Dean O, Kohlmann K, Jeavons S, Bush A, Copolov D

Department of Clinical and Biomedical Sciences - Barwon Health, University of Melbourne, Melbourne, Victoria, Australia. jason.thompson@srcentre.com.au.

A significant proportion of subjects drop out of medium to long-term clinical studies prior to trial completion. This may bias reported study outcomes... Read More

Source: PubMed

Turk Psikiyatri Derg    

[Schizophrenia or Frontotemporal Dementia in a Young Chinese Female: A purview of possible diagnoses].

Kanagasundram S

Frontotemporal dementia (FTD) is now increasingly being recognized as one of the causes of young onset dementia (YOD). The presentation of FTD can be ... Read More

Source: PubMed

Turk Psikiyatri Derg    

[Family to family support programs for the caregivers of schizophrenia patients: a systematic review].

Bademli K, Cetinkaya Duman Z

This systematic review aims to analyze the family to family support programs provided for the families of the schizophrenic patients and there potenti... Read More

Source: PubMed

Turk Psikiyatri Derg    

[The disrupted connection between cerebral hemispheres in schizophrenia patients: a diffusion tensor imaging study].

Kitis O, Eker MC, Zengin B, Akyilmaz DA, Yalvaç D, Ozdemir HI, Isman Haznedaroglu D, Bilgi MM, Gönül AS

In schizophrenia, the disruption of the communication between two brain hemispheres has not been shown clearly in the anatomical aspect despite other ... Read More

Source: PubMed

  2011 Dec 5  

Nicotine Reduces Antipsychotic-Induced Orofacial Dyskinesia in Rats.

Bordia T, McIntosh JM, Quik M

1 SRI International;

Antipsychotics are an important class of drugs for the management of schizophrenia and other psychotic disorders. They act by blocking dopamine recept... Read More

Source: PubMed

  2011 Dec 6  

Differences Between Victims of Bullying and Non-victims on Levels of Paranoid Ideation and Persecutory Symptoms, the Presence of Aggressive Traits, the Display of Social Anxiety and the Recall of Childhood Abuse Experiences in a Portuguese Mixed Clinical Sample.

Lopes BC

Faculdade de Psicologia e de Ciências da Educação, Universidade de Coimbra, Coimbra, Portugal. barbaracslopes@gmail.com.

BACKGROUND: Bullying has been considered as a traumatic experience that can lead to paranoid ideation in students (Campbell and Morrison, 2007). This ... Read More

Source: PubMed

  2011 Dec 5  

Who's left? Symptoms of schizophrenia that predict clinical trial dropout.

Thompson J, Berk M, Dean O, Kohlmann K, Jeavons S, Bush A, Copolov D

Department of Clinical and Biomedical Sciences - Barwon Health, University of Melbourne, Melbourne, Victoria, Australia. jason.thompson@srcentre.com.au.

A significant proportion of subjects drop out of medium to long-term clinical studies prior to trial completion. This may bias reported study outcomes... Read More

Source: PubMed

Turk Psikiyatri Derg    

[Schizophrenia or Frontotemporal Dementia in a Young Chinese Female: A purview of possible diagnoses].

Kanagasundram S

Frontotemporal dementia (FTD) is now increasingly being recognized as one of the causes of young onset dementia (YOD). The presentation of FTD can be ... Read More

Source: PubMed

Turk Psikiyatri Derg    

[Family to family support programs for the caregivers of schizophrenia patients: a systematic review].

Bademli K, Cetinkaya Duman Z

This systematic review aims to analyze the family to family support programs provided for the families of the schizophrenic patients and there potenti... Read More

Source: PubMed

Turk Psikiyatri Derg    

[The disrupted connection between cerebral hemispheres in schizophrenia patients: a diffusion tensor imaging study].

Kitis O, Eker MC, Zengin B, Akyilmaz DA, Yalvaç D, Ozdemir HI, Isman Haznedaroglu D, Bilgi MM, Gönül AS

In schizophrenia, the disruption of the communication between two brain hemispheres has not been shown clearly in the anatomical aspect despite other ... Read More

Source: PubMed

  2011 Dec 5  

Open conformation of human DOPA decarboxylase reveals the mechanism of PLP addition to Group II decarboxylases.

Giardina G, Montioli R, Gianni S, Cellini B, Paiardini A, Voltattorni CB, Cutruzzolà F

Dipartimento di Scienze Biochimiche 'A. Rossi Fanelli', Sapienza Università di Roma, Piazzale Aldo Moro 5, 00185 Rome, Italy.

DOPA decarboxylase, the dimeric enzyme responsible for the synthesis of neurotransmitters dopamine and serotonin, is involved in severe neurological d... Read More

Source: PubMed

  2011 Dec 6  

MK-801 alters Na(+), K (+)-ATPase activity and oxidative status in zebrafish brain: reversal by antipsychotic drugs.

Seibt KJ, da Luz Oliveira R, Rosemberg DB, Savio LE, Scherer EB, Schmitz F, Wyse AT, Bonan CD

Programa de Pós-Graduação em Biologia Celular e Molecular Laboratório de Neuroquímica e Psicofarmacologia, Departamento de Biologia Celular e Molecular, Faculdade de Biociências, Pontifícia Universidade Católica do Rio Grande do Sul, Avenida Ipiranga, 6681, Porto Alegre, RS, 90619-900, Brazil.

Schizophrenia is a debilitating mental disorder with a global prevalence of 1% and its etiology remains poorly understood. In the current study we inv... Read More

Source: PubMed

  2011 Nov 16  

Discovery of orally active pyrazoloquinolines as potent PDE10 inhibitors for the management of schizophrenia.

Yang SW, Smotryski J, McElroy WT, Tan Z, Ho G, Tulshian D, Greenlee WJ, Guzzi M, Zhang X, Mullins D, Xiao L, Hruza A, Chan TM, Rindgen D, Bleickardt C, Hodgson R

Department of Medicinal Chemistry, Merck Research Laboratories, 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States.

A series of pyrazoloquinoline analogs have been synthesized and shown to bind to PDE10 with high affinity. From the SAR study and our lead optimizatio... Read More

Source: PubMed

    

Reduced peak oxygen uptake and implications for cardiovascular health and quality of life in patients with schizophrenia.

Heggelund J, Hoff J, Helgerud J, Nilsberg GE, Morken G

ABSTRACT: BACKGROUND: Peak oxygen uptake (VO2peak) is a strong predictor of cardiovascular disease (CVD) and all-cause mortality, but is inadequately... Read More

Source: PubMed

  2011 Dec 5  

Open conformation of human DOPA decarboxylase reveals the mechanism of PLP addition to Group II decarboxylases.

Giardina G, Montioli R, Gianni S, Cellini B, Paiardini A, Voltattorni CB, Cutruzzolà F

Dipartimento di Scienze Biochimiche 'A. Rossi Fanelli', Sapienza Università di Roma, Piazzale Aldo Moro 5, 00185 Rome, Italy.

DOPA decarboxylase, the dimeric enzyme responsible for the synthesis of neurotransmitters dopamine and serotonin, is involved in severe neurological d... Read More

Source: PubMed

  2011 Dec 6  

MK-801 alters Na(+), K (+)-ATPase activity and oxidative status in zebrafish brain: reversal by antipsychotic drugs.

Seibt KJ, da Luz Oliveira R, Rosemberg DB, Savio LE, Scherer EB, Schmitz F, Wyse AT, Bonan CD

Programa de Pós-Graduação em Biologia Celular e Molecular Laboratório de Neuroquímica e Psicofarmacologia, Departamento de Biologia Celular e Molecular, Faculdade de Biociências, Pontifícia Universidade Católica do Rio Grande do Sul, Avenida Ipiranga, 6681, Porto Alegre, RS, 90619-900, Brazil.

Schizophrenia is a debilitating mental disorder with a global prevalence of 1% and its etiology remains poorly understood. In the current study we inv... Read More

Source: PubMed

  2011 Nov 16  

Discovery of orally active pyrazoloquinolines as potent PDE10 inhibitors for the management of schizophrenia.

Yang SW, Smotryski J, McElroy WT, Tan Z, Ho G, Tulshian D, Greenlee WJ, Guzzi M, Zhang X, Mullins D, Xiao L, Hruza A, Chan TM, Rindgen D, Bleickardt C, Hodgson R

Department of Medicinal Chemistry, Merck Research Laboratories, 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States.

A series of pyrazoloquinoline analogs have been synthesized and shown to bind to PDE10 with high affinity. From the SAR study and our lead optimizatio... Read More

Source: PubMed

    

Reduced peak oxygen uptake and implications for cardiovascular health and quality of life in patients with schizophrenia.

Heggelund J, Hoff J, Helgerud J, Nilsberg GE, Morken G

ABSTRACT: BACKGROUND: Peak oxygen uptake (VO2peak) is a strong predictor of cardiovascular disease (CVD) and all-cause mortality, but is inadequately... Read More

Source: PubMed


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Posted by:  mvkulk  Posted on: 09/12/2011
I feel harmones/vitamins/minerals may also play a role in SZ. what are the test can be conducted for male 28 years having SZ since 10 years mvkulk



Posted by:  mvkulk  Posted on: 09/12/2011
My son is diagnosied for SZ 10 years back. He is 28y now. What consultation treatment u can offer online??????? mvkulk



Posted by:  sonali77(Guest)  Posted on: 09/09/2011
my husband have a schizophrenia recently , we are decided for family planning ? will the child be normal ? or any crisis exist . can we wait for a time , how long ???



Posted by:  jameel_6358  Posted on: 01/10/2011
what are the drugs available in india for treating positive symptoms in Schizophrenia?



Posted by:  williamfallin  Posted on: 12/28/2010
I really love to read articles that have good information and ideas to custom logo design share to each reader. I hope to read more from you guys and continue that good work that is really inspiring to us.


Posted by:  dvill89(Guest)  Posted on: 12/31/2010
I learned so much from the article.I gained so much information
from that really informative article.Thanks for the post.Expect to read more.






Posted by:  Nishant_Sinha  Posted on: 08/23/2010
I am seeking help for my 28 year old brother-in-law who is suffering from schizophrenia and is under treatment for the past 6-7 months.His parents are no more and there is no one to look after him. I want to rehabilitate him as this is affecting my conjugal life.Please let me know the possible alternatives.


Posted by:  Filio  Posted on: 02/01/2012
Search with google "latest on schizophrenia" you will get many scientific guidance. I know what a pain it is for a family to have someone with schizophrenia. Good luck




Posted by:  alyssum  Posted on: 05/20/2010
I am looking for a Schizophrenia Support Group to help my 51 year old son who seems to get no help. His father had Chromosome 17 Dis-inhibition, Dementia, Parkinson disease, Atrophy Complex which has been 50% inherited. It was thought until Dec, 2008 that my son had this disorder, however it was diagnosed as Paranoid Schizophrenia then. My son is very sick and I can't seem to get help anywhere.


Posted by:  Filio  Posted on: 02/01/2012
Pls. check the list of support groups at http://www.medindia.net/patients/patientinfo/support_groups/Schizophrenia_unitedstates.htm




Posted by:  hlasny  Posted on: 06/01/2007
Hypofunction of glutamatergic neurons has been hypothesized to caused schizophrenia. For example, see conclusions from the symposium entitled, "Not Just Dopamine Any More: Emerging Glutamatergic Therapies for Schizophrenia," Calcium deficiency may be a predisposing or causative factor in schizophrenia ? This concept is based on the demonstration that „NMDA receptor hypofunction“ can be based on calcium-deficiency, potentiated by nutritional hypoproteinemia - chapter “Hyperfunction (Alzheimer’s disease and Parkinson disease) and hypofunction (schizophrenia) of glutamatergic neuronsâ€.



Posted by:  guest  Posted on: 04/22/2007
can ayurvedic medicine be used with allopathy medicine eg qutan


Posted by:  patanjali  Posted on: 10/13/2010
Ayurveda can be used with allopathy. you can even try along with homeopathy-but be careful as homeopathy will interact with allopathy, as homeopathy treats mind and body as one.i am speaking from personal experience of a family member




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