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PLoS ONE Reduced crowding and poor contour detection in schizophrenia are consistent with weak surround inhibition. Robol V, Tibber MS, Anderson EJ, Bobin T, Carlin P, Shergill SS, Dakin SC Department of General Psychology, University of Padua, Padua, Italy. Detection of visual contours (strings of small oriented elements) is markedly poor in schizophrenia. This has previously been attributed to an inabili... Read More Source: PubMed Exp Neurobiol Memantine reverses social withdrawal induced by ketamine in rats. Uribe E, Landaeta J, Wix R, Eblen A Laboratorio de Neurofisiología, Escuela De Ciencias Biomédicas y Tecnológicas Dr. Guillermo Mujica Sevilla, Facultad de Ciencias de la Salud, Universidad de Carabobo, Valencia, Venezuela. ; Hospital Dr. Rafael González Plaza, Departamento de Neuropsiquiatría. INSALUD, Gobernación del Estado Carabobo. Edo. Carabobo 2001, Venezuela. The objective of this study was to determine the effect of memantine on schizophrenia-like symptoms in a ketamine-induced social withdrawal model in r... Read More Source: PubMed Neuropharmacology 2013 Apr 11 NMDA receptors in nervous system diseases. Zhou Q, Sheng M Department of Neuroscience, Genentech Inc, 1 DNA Way, South San Francisco, CA 94080, USA. Electronic address: zhou.qiang@gene.com. NMDA receptor (NMDAR) dysfunction has emerged as a common theme in several major nervous system disorders, including ischemic brain injury, chronic ne... Read More Source: PubMed Prog. Neuropsychopharmacol. Biol. Psychiatry 2013 Apr 11 Association of serotonin transporter gene (SLC6A4) polymorphisms with schizophrenia susceptibility and symptoms in a Chinese-Han population. Li W, Yang Y, Lin J, Wang S, Zhao J, Yang G, Wang X, Ding M, Zhang H, Lv L Department of Psychiatry, Henan Mental Hospital ,The Second Affiliated Hospital of Xinxiang Medical University, Xinxiang, China; Henan Key Lab of Biological Psychiatry, Xinxiang Medical University, Xinxiang, China. Electronic address: lwq781603@163.com. Schizophrenia (SZ) is a complex psychiatric disorder with a strong genetic component. The serotonin transporter (SERT), encoded by solute carrier fami... Read More Source: PubMed Med. Hypotheses 2013 Apr 11 The ventral portion of the CA1 region of the hippocampus and the prefrontal cortex as candidate regions for neuromodulation in schizophrenia. Ewing SG, Winter C Bereich Experimentelle Psychiatrie, Universitätsklinik Carl Gustav Carus an der Technischen Universität Dresden, Fetscherstrasse 74, D-01307 Dresden, Germany. Electronic address: sam.ewing@gmail.com. Existing antipsychotic drugs are most effective in the treatment of the positive symptoms of schizophrenia. However, they are associated with consider... Read More Source: PubMed Schizophr. Res. 2013 Apr 9 Specific vs general cognitive remediation for executive functioning in schizophrenia: A multicenter randomized trial. Franck N, Duboc C, Sundby C, Amado I, Wykes T, Demily C, Launay C, Le Roy V, Bloch P, Willard D, Todd A, Petitjean F, Foullu S, Briant P, Grillon ML, Deppen P, Verdoux H, Bralet MC, Januel D, Riche B, Roy P, Vianin P Service Universitaire de Réhabilitation, CH Le Vinatier, Bron, France; Cognitive Neuroscience Centre, UMR 5229 CNRS & Claude Bernard University, Université de Lyon, Bron, France. Electronic address: nicolas.franck@ch-le-vinatier.fr. BACKGROUND: This study assesses the benefits of an individualized therapy (RECOS program) compared with the more general cognitive remediation therapy... Read More Source: PubMed Schizophr. Res. 2013 Apr 9 Paliperidone protects prefrontal cortical neurons from damages caused by MK-801 via Akt1/GSK3ß signaling pathway. Peng L, Zhu D, Feng X, Dong H, Yue Q, Zhang J, Gao Q, Hao J, Zhang X, Liu Z, Sun J Key Laboratory for Experimental Teratology of the Ministry of Education and Department of Anatomy, Shandong University School of Medicine, Jinan, Shandong 250012, China. Recent studies have suggested that neurodegeneration is involved in the pathogenesis of schizophrenia, and some atypical antipsychotics appear to prev... Read More Source: PubMed Neuron Imaging patients with psychosis and a mouse model establishes a spreading pattern of hippocampal dysfunction and implicates glutamate as a driver. Schobel SA, Chaudhury NH, Khan UA, Paniagua B, Styner MA, Asllani I, Inbar BP, Corcoran CM, Lieberman JA, Moore H, Small SA Department of Psychiatry, Columbia University Medical Center, New York, NY 10032, USA; The New York State Psychiatric Institute, New York, NY 10032, USA. The hippocampus in schizophrenia is characterized by both hypermetabolism and reduced size. It remains unknown whether these abnormalities are mechani... Read More Source: PubMed Neuron A mechanistic approach to preventing schizophrenia in at-risk individuals. Moghaddam B Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA 15260, USA. Electronic address: bita@pitt.edu. In this issue of Neuron, Schobel et al. (2013) report that excess hippocampal glutamate may cause transition to psychosis in individuals at high risk ... Read More Source: PubMed |
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Posted by:
mvkulk
Posted on: 09/12/2011 I feel harmones/vitamins/minerals may also play a role in SZ. what are the test can be conducted for male 28 years having SZ since 10 years
mvkulk
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Posted by:
jameel_6358
Posted on: 01/10/2011 what are the drugs available in india for treating positive symptoms in Schizophrenia?
Posted by:
williamfallin
Posted on: 12/28/2010 I really love to read articles that have good information and ideas to custom logo design share to each reader. I hope to read more from you guys and continue that good work that is really inspiring to us.
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Posted by:
Nishant_Sinha
Posted on: 08/23/2010 I am seeking help for my 28 year old brother-in-law who is suffering from schizophrenia and is under treatment for the past 6-7 months.His parents are no more and there is no one to look after him. I want to rehabilitate him as this is affecting my conjugal life.Please let me know the possible alternatives. |
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Posted by:
alyssum
Posted on: 05/20/2010 I am looking for a Schizophrenia Support Group to help my 51 year old son who seems to get no help. His father had Chromosome 17 Dis-inhibition, Dementia, Parkinson disease, Atrophy Complex which has been 50% inherited. It was thought until Dec, 2008 that my son had this disorder, however it was diagnosed as Paranoid Schizophrenia then. My son is very sick and I can't seem to get help anywhere. |
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Posted by:
hlasny
Posted on: 06/01/2007 Hypofunction of glutamatergic neurons has been hypothesized to caused schizophrenia. For example, see conclusions from the symposium entitled, "Not Just Dopamine Any More: Emerging Glutamatergic Therapies for Schizophrenia,"
Calcium deficiency may be a predisposing or causative factor in schizophrenia ?
This concept is based on the demonstration that „NMDA receptor hypofunction“ can be based on calcium-deficiency, potentiated by nutritional hypoproteinemia - chapter “Hyperfunction (Alzheimer’s disease and Parkinson disease) and hypofunction (schizophrenia) of glutamatergic neurons”.
Posted by:
guest
Posted on: 04/22/2007 can ayurvedic medicine be used with allopathy medicine eg qutan |
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