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Latest Publication and Research on Saint Johns Wort

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  2011 Nov 22  

Interaction of St John's wort (Hypericum perforatum) with clozapine.

Van Strater AC, Bogers JP

aDepartment Duin & Bollenstreek bDepartments of Haagstreek, Midden-Holland, and Duin & Bollenstreek, Psychiatric Centre Rivierduinen, The Netherlands.

St John's wort (Hypericum perforatum) is notorious for its ability to induce the enzymes of the P450 system. Especially, it induces CYP1A2 and CYP3A4,... Read More

Source: PubMed

BMC Fam Pract    

Treatment of depressive disorders in primary care - protocol of a multiple treatment systematic review of randomized controlled trials.

Linde K, Schumann I, Meissner K, Jamil S, Kriston L, Rücker G, Antes G, Schneider A

Institute of General Practice, Technische Universität München, Orleansstr, 47, D-81667 München, Germany. klaus.Linde@lrz.tum.de.

ABSTRACT:... Read More

Source: PubMed

ISRN Pharmacol    

Hypolipidemic and Antiobesity-Like Activity of Standardised Extract of Hypericum perforatum L. in Rats.

Husain GM, Chatterjee SS, Singh PN, Kumar V

Pharmacology Research Laboratory, Department of Pharmaceutics, Institute of Technology, Banaras Hindu University, Varanasi 221 005, India.

Hypericum perforatum is known to have diverse medicinal uses for centuries. The antidepressant activity of Hypericum perforatum is widely accepted and... Read More

Source: PubMed

  2011 Nov 14  

Norathyriol suppresses skin cancers induced by solar ultraviolet radiation by targeting ERK kinases.

Li J, Malakhova M, Mottamal M, Reddy K, Kurinov I, Carper A, Langfald A, Oi N, Kim MO, Zhu F, Sosa CP, Zhou K, Bode AM, Dong Z

University of Minnesota, The Hormel Institute.

Ultraviolet (UV) irradiation is the leading factor in the development of skin cancer, prompting great interest in chemopreventive agents for this dise... Read More

Source: PubMed

  2011 Nov 10  

An antibacterial from Hypericum acmosepalum inhibits ATP-dependent MurE ligase from Mycobacterium tuberculosis.

Osman K, Evangelopoulos D, Basavannacharya C, Gupta A, McHugh TD, Bhakta S, Gibbons S

Department of Pharmaceutical and Biological Chemistry, The School of Pharmacy, University of London, 29-39 Brunswick Square, Bloomsbury, London WC1N 1AX, UK; Institute of Structural and Molecular Biology, Department of Biological Sciences, Birkbeck, University of London, Malet Street, Bloomsbury, London WC1E 7HX, UK.

In a project to characterise new antibacterial chemotypes from plants, hyperenone A and hypercalin B were isolated from the hexane and chloroform extr... Read More

Source: PubMed

  2011 Nov 11  

Benzophenones and flavonoids from Hypericum maculatum and their antioxidant activities.

Zheleva-Dimitrova D, Nedialkov P, Girreser U, Kitanov G

a Department of Pharmacognosy, Faculty of Pharmacy , Medical University of Sofia , Dunav str. 2 , 1000 Sofia , Bulgaria.

The occurrence of three known benzophenones, namely annulatophenonoside, acetylannulatophenonoside and annulatophenone as well as a flavonol O-glycosi... Read More

Source: PubMed

  2011 Nov 10  

Prenylated Acylphloroglucinols, Chipericumins A-D, from Hypericum chinense.

Abe S, Tanaka N, Kobayashi J

Graduate School of Pharmaceutical Sciences, Hokkaido University , Sapporo 060-0812, Japan.

Two new tetracyclic prenylated acylphloroglucinols, chipericumins A (1) and B (2), were isolated from the roots of Hypericum chinense, together with t... Read More

Source: PubMed

Acta Pol Pharm    

Beneficial effect of Hypericum perforatum on depression and anxiety in a type 2 diabetic rat model.

Husain GM, Chatterjee SS, Singh PN, Kumar V

Pharmacology Research Laboratory, Department of Pharmaceutics, Institute of Technology, Banaras Hindu University, Varanasi-221 005, India.

Recent studies have revealed diverse therapeutically interesting pharmacological properties of a standardized Hypericum perforatum extract (HpE) poten... Read More

Source: PubMed

Acta Pol Pharm    

Beneficial effect of Hypericum perforatum on depression and anxiety in a type 2 diabetic rat model.

Husain GM, Chatterjee SS, Singh PN, Kumar V

Pharmacology Research Laboratory, Department of Pharmaceutics, Institute of Technology, Banaras Hindu University, Varanasi-221 005, India.

Recent studies have revealed diverse therapeutically interesting pharmacological properties of a standardized Hypericum perforatum extract (HpE) poten... Read More

Source: PubMed

  2011 Nov 21  

Production of biomass and useful compounds from adventitious roots of high-value added medicinal plants using bioreactor.

Baque MA, Moh SH, Lee EJ, Zhong JJ, Paek KY

Research Center for the Development of Advanced Horticultural Technology, Chungbuk National University, Cheongju 361-763, Republic of Korea; Department of Agronomy, Sher-e-Bangla Agricultural University, Sher-e-Bangla Nagar, Dhaka-1207, Bangladesh.

The increasing global demand for biomass of medicinal plant resources reflects the issues and crisis created by diminishing renewable resources and in... Read More

Source: PubMed

  2011 Nov 21  

Production of biomass and useful compounds from adventitious roots of high-value added medicinal plants using bioreactor.

Baque MA, Moh SH, Lee EJ, Zhong JJ, Paek KY

Research Center for the Development of Advanced Horticultural Technology, Chungbuk National University, Cheongju 361-763, Republic of Korea; Department of Agronomy, Sher-e-Bangla Agricultural University, Sher-e-Bangla Nagar, Dhaka-1207, Bangladesh.

The increasing global demand for biomass of medicinal plant resources reflects the issues and crisis created by diminishing renewable resources and in... Read More

Source: PubMed

  2011 Nov 25  

The essential oils of the aerial parts of two Hypericum taxa (Hypericum triquetrifolium and Hypericum aviculariifolium subsp. depilatum var. depilatum (Clusiaceae)) from Turkey.

Yuce E, Bagci E

a Tunceli Vocational School, Tunceli University , Tunceli , Turkey.

In this study, essential oil compositions of two Hypericum L. taxa (Hypericum triquetrifolium Turra. and Hypericum aviculariifolium Jaub. et Spach sub... Read More

Source: PubMed

  2011 Nov 25  

The essential oils of the aerial parts of two Hypericum taxa (Hypericum triquetrifolium and Hypericum aviculariifolium subsp. depilatum var. depilatum (Clusiaceae)) from Turkey.

Yuce E, Bagci E

a Tunceli Vocational School, Tunceli University , Tunceli , Turkey.

In this study, essential oil compositions of two Hypericum L. taxa (Hypericum triquetrifolium Turra. and Hypericum aviculariifolium Jaub. et Spach sub... Read More

Source: PubMed

  2011 Nov 22  

Interaction of St John's wort (Hypericum perforatum) with clozapine.

Van Strater AC, Bogers JP

aDepartment Duin & Bollenstreek bDepartments of Haagstreek, Midden-Holland, and Duin & Bollenstreek, Psychiatric Centre Rivierduinen, The Netherlands.

St John's wort (Hypericum perforatum) is notorious for its ability to induce the enzymes of the P450 system. Especially, it induces CYP1A2 and CYP3A4,... Read More

Source: PubMed

BMC Fam Pract    

Treatment of depressive disorders in primary care - protocol of a multiple treatment systematic review of randomized controlled trials.

Linde K, Schumann I, Meissner K, Jamil S, Kriston L, Rücker G, Antes G, Schneider A

Institute of General Practice, Technische Universität München, Orleansstr, 47, D-81667 München, Germany. klaus.Linde@lrz.tum.de.

ABSTRACT:... Read More

Source: PubMed

ISRN Pharmacol    

Hypolipidemic and Antiobesity-Like Activity of Standardised Extract of Hypericum perforatum L. in Rats.

Husain GM, Chatterjee SS, Singh PN, Kumar V

Pharmacology Research Laboratory, Department of Pharmaceutics, Institute of Technology, Banaras Hindu University, Varanasi 221 005, India.

Hypericum perforatum is known to have diverse medicinal uses for centuries. The antidepressant activity of Hypericum perforatum is widely accepted and... Read More

Source: PubMed

  2011 Nov 14  

Norathyriol suppresses skin cancers induced by solar ultraviolet radiation by targeting ERK kinases.

Li J, Malakhova M, Mottamal M, Reddy K, Kurinov I, Carper A, Langfald A, Oi N, Kim MO, Zhu F, Sosa CP, Zhou K, Bode AM, Dong Z

University of Minnesota, The Hormel Institute.

Ultraviolet (UV) irradiation is the leading factor in the development of skin cancer, prompting great interest in chemopreventive agents for this dise... Read More

Source: PubMed

  2011 Nov 10  

An antibacterial from Hypericum acmosepalum inhibits ATP-dependent MurE ligase from Mycobacterium tuberculosis.

Osman K, Evangelopoulos D, Basavannacharya C, Gupta A, McHugh TD, Bhakta S, Gibbons S

Department of Pharmaceutical and Biological Chemistry, The School of Pharmacy, University of London, 29-39 Brunswick Square, Bloomsbury, London WC1N 1AX, UK; Institute of Structural and Molecular Biology, Department of Biological Sciences, Birkbeck, University of London, Malet Street, Bloomsbury, London WC1E 7HX, UK.

In a project to characterise new antibacterial chemotypes from plants, hyperenone A and hypercalin B were isolated from the hexane and chloroform extr... Read More

Source: PubMed

  2011 Nov 11  

Benzophenones and flavonoids from Hypericum maculatum and their antioxidant activities.

Zheleva-Dimitrova D, Nedialkov P, Girreser U, Kitanov G

a Department of Pharmacognosy, Faculty of Pharmacy , Medical University of Sofia , Dunav str. 2 , 1000 Sofia , Bulgaria.

The occurrence of three known benzophenones, namely annulatophenonoside, acetylannulatophenonoside and annulatophenone as well as a flavonol O-glycosi... Read More

Source: PubMed

  2011 Nov 10  

Prenylated Acylphloroglucinols, Chipericumins A-D, from Hypericum chinense.

Abe S, Tanaka N, Kobayashi J

Graduate School of Pharmaceutical Sciences, Hokkaido University , Sapporo 060-0812, Japan.

Two new tetracyclic prenylated acylphloroglucinols, chipericumins A (1) and B (2), were isolated from the roots of Hypericum chinense, together with t... Read More

Source: PubMed


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