J. Med. Chem. 2020 Jan 30
Congenetic hybrids derived from dearomatized isoprenylated acylphloroglucinol with opposite effects on Cav3.1 low voltage-gated Ca2+ channel.
Ye YS, Li WY, Du SZ, Yang J, Nian Y, Xu G
A hybrid of dearomatized isoprenylated acylphloroglucinol (DIAP) and monoterpenoid, hypatone A (1), together with its biosynthetic analogues 2-4, are ...
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Source: PubMed
Pharmacol. Res. 2020 Jan 23
Hypericin attenuates nonalcoholic fatty liver disease and abnormal lipid metabolism via the PKA-mediated AMPK signaling pathway in vitro and in vivo.
Liang C, Li Y, Bai M, Huang Y, Yang H, Liu L, Wang S, Yu C, Song Z, Bao Y, Yi J, Sun L, Li Y
Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide and constitutes a major risk factor for progression to cirrhosis, ...
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Source: PubMed
Int. J. Syst. Evol. Microbiol. 2020 Jan 20
Hypericibacter terrae gen. nov., sp. nov. and Hypericibacter adhaerens sp. nov., two new members of the family Rhodospirillaceae isolated from the rhizosphere of Hypericum perforatum.
Noviana Z, Vieira S, Pascual J, Fobofou SAT, Rohde M, Spröer C, Bunk B, Overmann J
Two strains of the family Rhodospirillaceae were isolated from the rhizosphere of the medicinal plant Hypericum perforatum. Cells of both strains were ...
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Source: PubMed
Planta
Computational screening of miRNAs and their targets in leaves of Hypericum spp. by transcriptome-mining: a pilot study.
Petijová L, Jurcacková Z, Cellárová E
Our work provides a survey of mature miRNAs, their target genes and primary precursors identified by in-silico approach in leaf transcriptomes of five ...
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Source: PubMed
BMJ Open
Efficacy of a topical herbal and mineral formulation (Dynamiclear) for the treatment of herpes simplex labialis in the community setting: study protocol for a randomised, double-blind placebo-controlled trial.
Armour M, Semprini A, Ee C, MacCullagh L, Shortt N
Herpes simplex labialis (HSL) is a common infection that can cause painful lesions on the oral mucosa, commonly referred to as cold sores. Current bio ...
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Source: PubMed
