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Latest Publication and Research on Prostate Cancer

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  2011 Dec 5  

Caveolin-1 Upregulation Contributes to c-Myc-Induced High-Grade Prostatic Intraepithelial Neoplasia and Prostate Cancer.

Yang G, Goltsov AA, Ren C, Kurosaka S, Edamura K, Logothetis R, Demayo FJ, Troncoso P, Blando J, Digiovanni J, Thompson TC

UT M. D. Anderson Center.

Previously we reported caveolin-1 (Cav-1) overexpression in prostate cancer (PCa) cells and demonstrated that it promotes PCa progression. Here, we re... Read More

Source: PubMed

  2011 Dec 5  

Assessing the Clinical Role of Genetic Markers of Early-Onset Prostate Cancer Among High-Risk Men Enrolled in Prostate Cancer Early Detection.

Hughes L, Zhu F, Ross E, Gross L, Uzzo RG, Chen DY, Viterbo R, Rebbeck TR, Giri VN

1Cancer Prevention and Control, Fox Chase Cancer Center.

BACKGROUND: Men with familial prostate cancer (PCA) and African American men are at risk for developing PCA at younger ages. Genetic markers predictin... Read More

Source: PubMed

  2011 Dec 5  

[Evidence for the Digital Rectal Examination in the Emergency Assessment of Acute Abdominal Pain.]

Werner JC, Zock M, Khalil PN, Hoffmann J, Kanz KG, Jauch KW

Ludwig-Maximilians Universität, Klinik und Poliklinik für Chirurgie, Campus Innenstadt, München, Deutschland.

Background: Physical examination of patients with undifferentiated abdominal pain (UAP) in the emergency room traditionally calls for digital rectal e... Read More

Source: PubMed

  2011 Dec 6  

Effect of diallyl trisulfide derivatives on the induction of apoptosis in human prostate cancer PC-3 cells.

Chen M, Li B, Zhao X, Zuo H, He X, Li Z, Liu X, Chen L

College of Pharmaceutical Sciences, Southwest University, Chongqing, 400716, China.

The effects of five derivatives of diallyl trisulfide (DATS) were investigated on apoptosis in prostate cancer PC-3 cells, including dibutenyl trisulf... Read More

Source: PubMed

  2011 Dec 5  

Caveolin-1 Upregulation Contributes to c-Myc-Induced High-Grade Prostatic Intraepithelial Neoplasia and Prostate Cancer.

Yang G, Goltsov AA, Ren C, Kurosaka S, Edamura K, Logothetis R, Demayo FJ, Troncoso P, Blando J, Digiovanni J, Thompson TC

UT M. D. Anderson Center.

Previously we reported caveolin-1 (Cav-1) overexpression in prostate cancer (PCa) cells and demonstrated that it promotes PCa progression. Here, we re... Read More

Source: PubMed

  2011 Dec 5  

Assessing the Clinical Role of Genetic Markers of Early-Onset Prostate Cancer Among High-Risk Men Enrolled in Prostate Cancer Early Detection.

Hughes L, Zhu F, Ross E, Gross L, Uzzo RG, Chen DY, Viterbo R, Rebbeck TR, Giri VN

1Cancer Prevention and Control, Fox Chase Cancer Center.

BACKGROUND: Men with familial prostate cancer (PCA) and African American men are at risk for developing PCA at younger ages. Genetic markers predictin... Read More

Source: PubMed

  2011 Dec 5  

[Evidence for the Digital Rectal Examination in the Emergency Assessment of Acute Abdominal Pain.]

Werner JC, Zock M, Khalil PN, Hoffmann J, Kanz KG, Jauch KW

Ludwig-Maximilians Universität, Klinik und Poliklinik für Chirurgie, Campus Innenstadt, München, Deutschland.

Background: Physical examination of patients with undifferentiated abdominal pain (UAP) in the emergency room traditionally calls for digital rectal e... Read More

Source: PubMed

Cell Biochem. Funct.    

CrkI and p130(Cas) complex regulates the migration and invasion of prostate cancer cells.

Dai Y, Qi L, Zhang X, Li Y, Chen M, Zu X

Department of Urology, Xiangya Hospital, Central South University, Hunan, China.

Prostate cancer metastasis is often associated with poor prognosis. The molecular coupling of the adaptor protein Crk to the docking protein p130(Cas)... Read More

Source: PubMed

Cell Biochem. Funct.    

CrkI and p130(Cas) complex regulates the migration and invasion of prostate cancer cells.

Dai Y, Qi L, Zhang X, Li Y, Chen M, Zu X

Department of Urology, Xiangya Hospital, Central South University, Hunan, China.

Prostate cancer metastasis is often associated with poor prognosis. The molecular coupling of the adaptor protein Crk to the docking protein p130(Cas)... Read More

Source: PubMed

  2011 Dec 5  

ProsCan for Couples: a feasibility study for evaluating peer support within a controlled research design.

Chambers SK, Schover L, Halford K, Ferguson M, Gardiner R, Occhipinti S, Dunn J

Griffith Health Institute, Griffith University, Brisbane, Australia; Viertel Centre for Research in Cancer Control, Cancer Council Queensland, Brisbane, Australia. suzanne.chambers@griffith.edu.au.

Background: The present study assessed the feasibility of delivering peer support for couples coping with prostate cancer within a trial design. Metho... Read More

Source: PubMed

  2011 Dec 5  

ProsCan for Couples: a feasibility study for evaluating peer support within a controlled research design.

Chambers SK, Schover L, Halford K, Ferguson M, Gardiner R, Occhipinti S, Dunn J

Griffith Health Institute, Griffith University, Brisbane, Australia; Viertel Centre for Research in Cancer Control, Cancer Council Queensland, Brisbane, Australia. suzanne.chambers@griffith.edu.au.

Background: The present study assessed the feasibility of delivering peer support for couples coping with prostate cancer within a trial design. Metho... Read More

Source: PubMed

  2011 Dec 6  

NutriTRAILomics in prostate cancer: time to have two strings to one's bow.

Farooqi AA, Rana A, Riaz AM, Khan A, Ali M, Javed S, Mukhtar S, Minhaj S, Rao JR, Rajpoot J, Amber R, Javed FA, Waqar-Un-Nisa, Khanum R, Bhatti S

Institute of Molecular Biology and Biotechnology (IMBB), The University of Lahore, Lahore, Pakistan, ammadahmad638@yahoo.com.

The astonishing development of broad genomics and proteomics tools have catalyzed a new era in both therapeutic interventions and nutrition in prostat... Read More

Source: PubMed

  2011 Dec 6  

NutriTRAILomics in prostate cancer: time to have two strings to one's bow.

Farooqi AA, Rana A, Riaz AM, Khan A, Ali M, Javed S, Mukhtar S, Minhaj S, Rao JR, Rajpoot J, Amber R, Javed FA, Waqar-Un-Nisa, Khanum R, Bhatti S

Institute of Molecular Biology and Biotechnology (IMBB), The University of Lahore, Lahore, Pakistan, ammadahmad638@yahoo.com.

The astonishing development of broad genomics and proteomics tools have catalyzed a new era in both therapeutic interventions and nutrition in prostat... Read More

Source: PubMed

  2011 Dec 6  

Immunocapture of prostate cancer cells by use of anti-PSMA antibodies in microdevices.

Santana SM, Liu H, Bander NH, Gleghorn JP, Kirby BJ

Sibley School of Mechanical and Aerospace Engineering, Cornell University, 245 Upson Hall, Ithaca, NY, 14853, USA, sms492@cornell.edu.

Patients suffering from cancer can shed tumor cells into the bloodstream, leading to one of the most important mechanisms of metastasis. As such, the ... Read More

Source: PubMed

  2011 Dec 6  

Immunocapture of prostate cancer cells by use of anti-PSMA antibodies in microdevices.

Santana SM, Liu H, Bander NH, Gleghorn JP, Kirby BJ

Sibley School of Mechanical and Aerospace Engineering, Cornell University, 245 Upson Hall, Ithaca, NY, 14853, USA, sms492@cornell.edu.

Patients suffering from cancer can shed tumor cells into the bloodstream, leading to one of the most important mechanisms of metastasis. As such, the ... Read More

Source: PubMed

N. Z. Med. J.    

Screening for prostate cancer is not recommended.

Barendregt JJ

School of Population Health, University of Queensland, Brisbane, Australia.

... Read More

Source: PubMed

N. Z. Med. J.    

Screening for prostate cancer is not recommended.

Barendregt JJ

School of Population Health, University of Queensland, Brisbane, Australia.

... Read More

Source: PubMed

  2011 Dec 5  

Dopamine stabilizes tumor blood vessels by up-regulating angiopoietin 1 expression in pericytes and Kruppel-like factor-2 expression in tumor endothelial cells.

Chakroborty D, Sarkar C, Yu H, Wang J, Liu Z, Dasgupta PS, Basu S

Department of Pathology, Ohio State University, Columbus, OH 43210.

Impaired blood flow in the tumor vascular bed caused by structurally and functionally abnormal blood vessels not only hinders the delivery of chemothe... Read More

Source: PubMed

  2011 Dec 5  

Dopamine stabilizes tumor blood vessels by up-regulating angiopoietin 1 expression in pericytes and Kruppel-like factor-2 expression in tumor endothelial cells.

Chakroborty D, Sarkar C, Yu H, Wang J, Liu Z, Dasgupta PS, Basu S

Department of Pathology, Ohio State University, Columbus, OH 43210.

Impaired blood flow in the tumor vascular bed caused by structurally and functionally abnormal blood vessels not only hinders the delivery of chemothe... Read More

Source: PubMed

  2011 Dec 6  

Effect of diallyl trisulfide derivatives on the induction of apoptosis in human prostate cancer PC-3 cells.

Chen M, Li B, Zhao X, Zuo H, He X, Li Z, Liu X, Chen L

College of Pharmaceutical Sciences, Southwest University, Chongqing, 400716, China.

The effects of five derivatives of diallyl trisulfide (DATS) were investigated on apoptosis in prostate cancer PC-3 cells, including dibutenyl trisulf... Read More

Source: PubMed


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If you have a question about health related issues, you can now post it in our Ask An Expert section on our community website Medwonders.com and get answers from our panel of experts.
Posted by:  prema  Posted on: 01/18/2010
Abiraterone in prostate cancer

The big news in oncology has been Johnson and Johnson purchasing Cougar Biotechnology for $1 billion. They have just bought promising prostate cancer compound, abiraterone.

So look out for this oral drug.

Dr.Shroff
The data hasn't even been announced at ASCO yet, that's this weekend coming, so one can only speculate that suitors got a sneak peek of the data under an NDA. A billion dollars certainly gets attention and raises the ante for future small oncology biotech deals.




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