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Latest Publication and Research on Leprosy

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Pan Afr Med J    

From DOTS to the Stop TB Strategy: DOTS coverage and trend of tuberculosis notification in Ebonyi, southeastern Nigeria, 1998-2009.

Ukwaja K, Alobu I, Ifebunandu N, Osakwe C, Igwenyi C

Department of Internal Medicine, Ebonyi State University Teaching Hospital Abakaliki, Ebonyi State, Nigeria.

Nigeria ranks fourth among the 22 high tuberculosis (TB) burden countries. The estimated incidence of all TB cases in 2009 was 311/100,000 population.... Read More

Source: PubMed

Pan Afr Med J    

Elimination of Leprosy as a public health problem by 2000 AD: an epidemiological perspective.

Nsagha DS, Bamgboye EA, Assob JC, Njunda AL, Kamga HL, Zoung-Kanyi Bissek AC, Tabah EN, Oyediran AB, Njamnshi AK

Department of Public Health and Hygiene, Faculty of Health Sciences, University of Buea, Buea, Cameroon.

Leprosy is caused by Mycobacterium leprae and manifests as damage to the skin and peripheral nerves. The disease is dreaded because it causes deformit... Read More

Source: PubMed

  2011 Dec 5  

Peptides of Lsr2 of Mycobacterium leprae show hierarchical responses in lymphoproliferative assays with selective recognition by anergic lepromatous leprosy patients.

Chaduvula M, Murtaza A, Misra N, Narayan NP, Ramesh V, Prasad HK, Rani R, Chinnadurai RK, Nath I

National Institute of Pathology, Safdarjung Hospital Campus.

Lsr2 protein of Mycobacterium leprae (ML) was shown earlier to elicit B and T cell responses in leprosy patients (20, 28). Lymphproliferation to ML an... Read More

Source: PubMed

Am. J. Trop. Med. Hyg.    

Mycobacterium ulcerans Infection (Buruli Ulcer) on the Face: A Comparative Analysis of 13 Clinically Suspected Cases from the Democratic Republic of Congo.

Phanzu DM, Mahema RL, Suykerbuyk P, Imposo DH, Lehman LF, Nduwamahoro E, Meyers WM, Boelaert M, Portaels F

Institut Médical Evangélique, Kimpese Hospital, Kimpese, Bas-Congo, Democratic Republic of Congo; American Leprosy Missions, Greenville, South Carolina; Department of Environmental and Infectious Disease Sciences, Armed Forces Institute of Pathology, Washington, District of Columbia; Epidemiology and Disease Control Unit, Department of Public Health, and Mycobacteriology Unit, Department of Microbiology, Institute of Tropical Medicine, Antwerp, Belgium.

Abstract. We report our experience in managing 13 consecutive clinically suspected cases of Buruli ulcer on the face treated at the hospital of the In... Read More

Source: PubMed

  2011 Dec 5  

Increasing access to the MDR-TB surveillance programme through a collaborative model in western Kenya.

Park PH, Magut C, Gardner A, O'yiengo DO, Kamle L, Langat BK, Buziba NG, Carter EJ

Duke University Medical Center, Durham, NC, USA Moi University School of Medicine, Eldoret, Kenya Warren Alpert Medical School of Brown University, Providence, RI, USA Division of Leprosy, Tuberculosis, and Lung Disease, Nairobi, Kenya.

Objective Kenya, like many resource-constrained countries, has a single mycobacterial laboratory, centrally located in Nairobi, with capacity for dru... Read More

Source: PubMed

  2011 Nov 20  

Mycobacterium indicus pranii downregulates MMP-9 and iNOS through COX-2 dependent and TNF-a independent pathway in mouse peritoneal macrophages in vitro.

Pandey RK, Dahiya Y, Sodhi A

School of Biotechnology, Faculty of Science, Banaras Hindu University, Varanasi 221005, India.

Despite the popular belief that granulomas are innate immune mechanism to restrict mycobacterial growth, evidences suggest that granulomas facilitate ... Read More

Source: PubMed

Dermatol. Online J.    

Letter: Docetaxel-induced supravenous serpentine dermatitis.

Ghosh SK, Bandyopadhyay D, Ghoshal L, Basu S

Department of Dermatology, Venereology, and Leprosy, R G Kar Medical College, Kolkata, India.

Serpentine erythematous or hyperpigmented streaks along the superficial venous network proximal to the site of injection may occur as a distinctive er... Read More

Source: PubMed

  2011 Dec 5  

Increasing access to the MDR-TB surveillance programme through a collaborative model in western Kenya.

Park PH, Magut C, Gardner A, O'yiengo DO, Kamle L, Langat BK, Buziba NG, Carter EJ

Duke University Medical Center, Durham, NC, USA Moi University School of Medicine, Eldoret, Kenya Warren Alpert Medical School of Brown University, Providence, RI, USA Division of Leprosy, Tuberculosis, and Lung Disease, Nairobi, Kenya.

Objective Kenya, like many resource-constrained countries, has a single mycobacterial laboratory, centrally located in Nairobi, with capacity for dru... Read More

Source: PubMed

  2011 Nov 20  

Mycobacterium indicus pranii downregulates MMP-9 and iNOS through COX-2 dependent and TNF-a independent pathway in mouse peritoneal macrophages in vitro.

Pandey RK, Dahiya Y, Sodhi A

School of Biotechnology, Faculty of Science, Banaras Hindu University, Varanasi 221005, India.

Despite the popular belief that granulomas are innate immune mechanism to restrict mycobacterial growth, evidences suggest that granulomas facilitate ... Read More

Source: PubMed

Dermatol. Online J.    

Letter: Docetaxel-induced supravenous serpentine dermatitis.

Ghosh SK, Bandyopadhyay D, Ghoshal L, Basu S

Department of Dermatology, Venereology, and Leprosy, R G Kar Medical College, Kolkata, India.

Serpentine erythematous or hyperpigmented streaks along the superficial venous network proximal to the site of injection may occur as a distinctive er... Read More

Source: PubMed

PLoS Negl Trop Dis    

A Lipopeptide Facilitate Induction of Mycobacterium leprae Killing in Host Cells.

Maeda Y, Tamura T, Fukutomi Y, Mukai T, Kai M, Makino M

Department of Mycobacteriology, Leprosy Research Center, National Institute of Infectious Diseases, Tokyo, Japan.

Little is known of the direct microbicidal activity of T cells in leprosy, so a lipopeptide consisting of the N-terminal 13 amino acids lipopeptide (L... Read More

Source: PubMed

  2011 Dec 1  

Seagrass as a potential source of natural antioxidant and anti-inflammatory agents.

Yuvaraj N, Kanmani P, Satishkumar R, Paari A, Pattukumar V, Arul V

Department of Biotechnology, Pondicherry University , Puducherry , India.

Context: Halophila spp. is a strong medicine against malaria and skin diseases and is found to be very effective in early stages of leprosy. Seagrasse... Read More

Source: PubMed

  2011 Nov 23  

Potential of Mycobacterium vanbaalenii as a model organism to study drug transporters of Mycobacterium tuberculosis, Mycobacterium marinum and Mycobacterium ulcerans: Homology analysis of M. tuberculosis drug transporters among mycobacterial species.

Gupta AK, Katoch VM, Chauhan DS, Lavania M

Department of Microbiology & Molecular Biology, National JALMA Institute for Leprosy & Other Mycobacterial Diseases (NJILOMD), Tajganj, Agra 282001, India.

Drug efflux pumps have been one of the important mechanisms of drug resistance in Mycobacterium tuberculosis. There is a prerequisite to study the beh... Read More

Source: PubMed

Pan Afr Med J    

From DOTS to the Stop TB Strategy: DOTS coverage and trend of tuberculosis notification in Ebonyi, southeastern Nigeria, 1998-2009.

Ukwaja K, Alobu I, Ifebunandu N, Osakwe C, Igwenyi C

Department of Internal Medicine, Ebonyi State University Teaching Hospital Abakaliki, Ebonyi State, Nigeria.

Nigeria ranks fourth among the 22 high tuberculosis (TB) burden countries. The estimated incidence of all TB cases in 2009 was 311/100,000 population.... Read More

Source: PubMed

Pan Afr Med J    

Elimination of Leprosy as a public health problem by 2000 AD: an epidemiological perspective.

Nsagha DS, Bamgboye EA, Assob JC, Njunda AL, Kamga HL, Zoung-Kanyi Bissek AC, Tabah EN, Oyediran AB, Njamnshi AK

Department of Public Health and Hygiene, Faculty of Health Sciences, University of Buea, Buea, Cameroon.

Leprosy is caused by Mycobacterium leprae and manifests as damage to the skin and peripheral nerves. The disease is dreaded because it causes deformit... Read More

Source: PubMed

  2011 Dec 5  

Peptides of Lsr2 of Mycobacterium leprae show hierarchical responses in lymphoproliferative assays with selective recognition by anergic lepromatous leprosy patients.

Chaduvula M, Murtaza A, Misra N, Narayan NP, Ramesh V, Prasad HK, Rani R, Chinnadurai RK, Nath I

National Institute of Pathology, Safdarjung Hospital Campus.

Lsr2 protein of Mycobacterium leprae (ML) was shown earlier to elicit B and T cell responses in leprosy patients (20, 28). Lymphproliferation to ML an... Read More

Source: PubMed

Am. J. Trop. Med. Hyg.    

Mycobacterium ulcerans Infection (Buruli Ulcer) on the Face: A Comparative Analysis of 13 Clinically Suspected Cases from the Democratic Republic of Congo.

Phanzu DM, Mahema RL, Suykerbuyk P, Imposo DH, Lehman LF, Nduwamahoro E, Meyers WM, Boelaert M, Portaels F

Institut Médical Evangélique, Kimpese Hospital, Kimpese, Bas-Congo, Democratic Republic of Congo; American Leprosy Missions, Greenville, South Carolina; Department of Environmental and Infectious Disease Sciences, Armed Forces Institute of Pathology, Washington, District of Columbia; Epidemiology and Disease Control Unit, Department of Public Health, and Mycobacteriology Unit, Department of Microbiology, Institute of Tropical Medicine, Antwerp, Belgium.

Abstract. We report our experience in managing 13 consecutive clinically suspected cases of Buruli ulcer on the face treated at the hospital of the In... Read More

Source: PubMed

PLoS Negl Trop Dis    

A Lipopeptide Facilitate Induction of Mycobacterium leprae Killing in Host Cells.

Maeda Y, Tamura T, Fukutomi Y, Mukai T, Kai M, Makino M

Department of Mycobacteriology, Leprosy Research Center, National Institute of Infectious Diseases, Tokyo, Japan.

Little is known of the direct microbicidal activity of T cells in leprosy, so a lipopeptide consisting of the N-terminal 13 amino acids lipopeptide (L... Read More

Source: PubMed

  2011 Dec 1  

Seagrass as a potential source of natural antioxidant and anti-inflammatory agents.

Yuvaraj N, Kanmani P, Satishkumar R, Paari A, Pattukumar V, Arul V

Department of Biotechnology, Pondicherry University , Puducherry , India.

Context: Halophila spp. is a strong medicine against malaria and skin diseases and is found to be very effective in early stages of leprosy. Seagrasse... Read More

Source: PubMed

  2011 Nov 23  

Potential of Mycobacterium vanbaalenii as a model organism to study drug transporters of Mycobacterium tuberculosis, Mycobacterium marinum and Mycobacterium ulcerans: Homology analysis of M. tuberculosis drug transporters among mycobacterial species.

Gupta AK, Katoch VM, Chauhan DS, Lavania M

Department of Microbiology & Molecular Biology, National JALMA Institute for Leprosy & Other Mycobacterial Diseases (NJILOMD), Tajganj, Agra 282001, India.

Drug efflux pumps have been one of the important mechanisms of drug resistance in Mycobacterium tuberculosis. There is a prerequisite to study the beh... Read More

Source: PubMed


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If you have a question about health related issues, you can now post it in our Ask An Expert section on our community website Medwonders.com and get answers from our panel of experts.
Posted by:  gayani(Guest)  Posted on: 06/09/2010
Is it dangerous in any way to make a patient who is undergoing treatment take up writing exercises as physiotherapy to get the fingers working again?The fingers are clawed in the right hand and the patient has been asked o come in for physiotherapy sessions as well



Posted by:  innocent14  Posted on: 03/17/2010
Thanks a lot for providing qualitative & updated news about leprosy.Really this website has enhanced my leprosy knowledge.



Posted by:  dearmehraj(Guest)  Posted on: 09/07/2009
i am a medical student requires a detail study of leprosy for seminar & i found your website very informative. Thank you, best regards.



Posted by:  dearmehraj(Guest)  Posted on: 09/07/2009
M a medical student requires a detail study of leprosy for seminar & i found your website very informative.Thank you,best regards.



Posted by:  guest  Posted on: 05/07/2009
I'm a physician on speciality study on Dermatovenereology & i found your website very much helpful & updating in my study & i thank you very much & keep it up.


Posted by:  guest  Posted on: 06/15/2010
How is your study coming along? Would you be willing to submit a paper about it to our journal: SkinMed?




Posted by:  visuth_79  Posted on: 11/14/2008
i am infected hansen disease(BL)since 2003 and i take my MDT from 2005 to 2007 but problem is some nodules appears in my body, when i take prednisolene then its disappear,so, please tell me can i prevent this disease and how long i take prednisolene?



Posted by:  guest  Posted on: 03/05/2008
well.... i find your website very educational.i was reading about my disease (leprosy) and i found out alot of interesting facts. thanks to you...,i have been cured! god bless your soul!




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