Cancer 2013 Apr 12
Tubulin-ß-III overexpression by uterine serous carcinomas is a marker for poor overall survival after platinum/taxane chemotherapy and sensitivity to epothilones.
Roque DM, Bellone S, English DP, Buza N, Cocco E, Gasparrini S, Bortolomai I, Ratner E, Silasi DA, Azodi M, Rutherford TJ, Schwartz PE, Santin AD
Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut.
BACKGROUND: Uterine serous carcinoma (USC) is a subtype of endometrial cancer associated with chemoresistance and poor outcome. Overexpression of tubu...
Fam. Cancer 2013 Apr 13
Self administered screening for hereditary cancers in conjunction with mammography and ultrasound.
McDonnell CH, Seidenwurm DJ, McDonnell DE, Bobolis KA
Radiological Associates of Sacramento Medical Group, Inc., 1500 Expo Parkway, Sacramento, CA, 95815, USA, firstname.lastname@example.org.
We evaluated the feasibility of an automated tablet computer application providing a family and personal history based cancer risk assessment for here...
Eur. J. Cancer 2013 Apr 11
Impact of weight change and weight cycling on risk of different subtypes of endometrial cancer.
Nagle CM, Marquart L, Bain CJ, O'Brien S, Lahmann PH, Quinn M, Oehler MK, Obermair A, Spurdle AB, Webb PM
Population Health Department, Queensland Institute of Medical Research, Brisbane, Queensland, Australia. Electronic address: Christina.Nagle@qimr.edu.au.
AIM: Obesity is an established risk factor for endometrial cancer. Associations tend to be stronger for the endometrioid subtype. The role of adult we...
Gynecol. Oncol. 2013 Apr 10
Robotic single-site hysterectomy (RSS-H) vs. laparoendoscopic single-site hysterectomy (LESS-H) in early endometrial cancer: A double-Institution case-control study.
Fagotti A, Corrado G, Fanfani F, Paglia A, Vizzielli G, Sindico S, Scambia G, Vizza E
Gynecologic Oncologic Unit, Catholic University of the Sacred Heart, Rome, Italy. Electronic address: email@example.com.
OBJECTIVE: To report our experience with single-site robotic platform for IS3000 "Da Vinci" Si Surgical System to perform robotic single site hysterec...
Am. J. Obstet. Gynecol. 2013 Apr 10
Predictive value of serum HE4 and CA125 concentrations in endometrial carcinoma.
Saarelainen SK, Peltonen N, Lehtimäki T, Perheentupa A, Vuento MH, Mäenpää JU
Department of Obstetrics and Gynecology, Tampere University Hospital, Tampere, Finland. Electronic address: firstname.lastname@example.org.
OBJECTIVE: To evaluate the performance of preoperative serum levels of human epididymis protein 4 (HE4) and cancer antigen 125 (CA125) in predicting t...
Int. J. Radiat. Oncol. Biol. Phys.
Hematologic Toxicity in RTOG 0418: A Phase 2 Study of Postoperative IMRT for Gynecologic Cancer.
Klopp AH, Moughan J, Portelance L, Miller BE, Salehpour MR, Hildebrandt E, Nuanjing J, D'Souza D, Souhami L, Small W, Gaur R, Jhingran A
The University of Texas MD Anderson Cancer Center, Houston, Texas. Electronic address: email@example.com.
Intensity modulated radiation therapy (IMRT), compared with conventional 4-field treatment, can reduce the volume of bone marrow irradiated. Pelvic bo...
Endocrinology 2013 Apr 11
The AF-1 activation function of estrogen receptor alpha is necessary and sufficient for uterine epithelial cell proliferation in vivo.
Abot A, Fontaine C, Raymond-Letron I, Flouriot G, Adlanmerini M, Buscato M, Otto C, Bergès H, Laurell H, Gourdy P, Lenfant F, Arnal JF
*INSERM U1048, Institut des Maladies Métaboliques et Cardiovasculaires, UPS, BP 84225, 31 432 Toulouse cedex 04, France;
Estrogen receptor-a (ERa) regulates gene transcription through the two activation functions (AF) AF-1 and AF-2. The crucial role of ERaAF-2 was previo...
Genes Chromosomes Cancer 2013 Apr 12
Fusion of the ZC3H7B and BCOR genes in endometrial stromal sarcomas carrying an X;22-translocation.
Panagopoulos I, Thorsen J, Gorunova L, Haugom L, Bjerkehagen B, Davidson B, Heim S, Micci F
Section for Cancer Cytogenetics, Institute for Medical Informatics, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway; Centre for Cancer Biomedicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
Endometrial stromal sarcomas (ESS) are genetically heterogeneous uterine tumors in which a JAZF1-SUZ12 chimeric gene resulting from the chromosomal tr...
J. Korean Med. Sci.
The Synergistic Apoptotic Interaction of Indole-3-Carbinol and Genistein with TRAIL on Endometrial Cancer Cells.
Parajuli B, Shin SJ, Kwon SH, Cha SD, Lee HG, Bae I, Cho CH
Department of Obstetrics and Gynecology, Keimyung University, School of Medicine, Daegu, Korea.
Induction of apoptosis in target cells is a key mechanism by which chemotherapy promotes cell killing. The purpose of this study was to determine whet...
Cancer Causes Control 2013 Apr 12
The association of active smoking with multiple cancers: national census-cancer registry cohorts with quantitative bias analysis.
Blakely T, Barendregt JJ, Foster RH, Hill S, Atkinson J, Sarfati D, Edwards R
Department of Public Health, University of Otago, PO Box 7343, Wellington, New Zealand, firstname.lastname@example.org.
PURPOSES: (1) Determine the association of multiple cancers with smoking, focusing on cancers with an uncertain association; and (2) illustrate quanti...