login
Become a member
Quick Registration
Full Registration Benefits -
Free Homepages for Doctors
Free Homepages for Hospitals
Free Homepages for Medical Conference
Free Homepages for NGO's
Personal Health Record Creation
Access to all Medical Slides
Access to all Jobs & Products Sale
| Disease Info Index | ||||||||||||||||||||||||||
|
|
Drug Toxicity
Page Options
Drugs For Drug Toxicity
Drug Toxicity
Latest Publication and Research on Drug Toxicity
|
|
|
Text 
|
Prague Med Rep Ameliorative Effects of Curcumin on the Spermatozoon Tail Length, Count, Motility and Testosterone Serum Level in Metronidazole-treated Mice. Karbalay-Doust S, Noorafshan A Histomorphometry and Stereology Research Centre, Shiraz University of Medical Sciences, Shiraz, Iran. Metronidazole (MTZ) is used as an antiparasitic drug. Curcumin is considered as anti-oxidant and anti-inflammatory agent. The ameliorative e... Read More Source: PubMed 2011 Dec 5 Natural polyphenols in cancer therapy. Asensi M, Ortega A, Mena S, Feddi F, Estrela JM Department of Physiology, University of Valencia , Valencia , Spain. Natural polyphenols are secondary metabolites of plants involved in defense against different types of stress. Extracts containing these compounds hav... Read More Source: PubMed 2011 Dec 3 Aptamer-conjugated and drug-loaded acoustic droplets for ultrasound theranosis. Wang CH, Kang ST, Lee YH, Luo YL, Huang YF, Yeh CK Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, 101, Section 2, Kuang-Fu Road, Hsinchu 30013, Taiwan, ROC. Tumor therapy requires multi-functional treatment strategies with specific targeting of therapeutics to reduce general toxicity and increase efficacy.... Read More Source: PubMed Attenuation of Cytotoxic Natural Product DNA Intercalating Agents by Caffeine. Hill GM, Moriarity DM, Setzer WN Department of Chemistry, University of Alabama in Huntsville, Huntsville, Alabama 35899, USA. Many anti-tumor drugs function by intercalating into DNA. The xanthine alkaloid caffeine can also intercalate into DNA as well as form p-p molecular c... Read More Source: PubMed Am. J. Trop. Med. Hyg. Review: improving the therapeutic index of 8-aminoquinolines by the use of drug combinations: review of the literature and proposal for future investigations. Myint HY, Berman J, Walker L, Pybus B, Melendez V, Baird JK, Ohrt C Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, Maryland; National Center for Natural Products Research and Department of Pharmacology, School of Pharmacy, University of Mississippi, University, Mississippi; Eijkman-Oxford Clinical Research Unit, Jalan Diponegoro No. 69, Jakarta, Indonesia; Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom. Abstract. Because 8-aminoquinolines affect critical survival stages of Plasmodium parasites, treatment and control of malaria could be markedly improv... Read More Source: PubMed 2011 Dec 6 Modified Natural Clinoptilolite Detoxifies Small Mammal's Organism Loaded with Lead II: Genetic, Cell, and Physiological Effects. Topashka-Ancheva M, Beltcheva M, Metcheva R, Rojas JA, Rodriguez-De la Fuente AO, Gerasimova T, Rodríguez-Flores LE, Teodorova SE Institute of Biodiversity and Ecosystem Research, Bulgarian Academy of Sciences, 1, Tzar Osvoboditel Blvd., 1000, Sofia, Bulgaria. The detoxification capacity of the clinoptilolite modification KLS-10-MA used as food additive in small mammals, chronically lead-exposed, was proven ... Read More Source: PubMed N. Z. Med. J. Over-the-counter codeine analgesic misuse and harm: characteristics of cases in Australia and New Zealand. McAvoy BR, Dobbin MD, Tobin CL Tasmanian Department of Health and Human Services, Alcohol and Drug Services, Level 2, Carruthers Building, St Johns Park, New Town, Hobart, Tasmania 7008, Australia. brian.mcavoy@dhhs.tas.gov.au. To describe the characteristics of clients addicted to over-the-counter (OTC) codeine analgesics presenting to an Auckland open-access clinic, and to ... Read More Source: PubMed 2011 Dec 5 Dynamic metabolic labeling of DNA in vivo with arabinosyl nucleosides. Neef AB, Luedtke NW Institute of Organic Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland. Commonly used metabolic labels for DNA, including 5-ethynyl-2'-deoxyuridine (EdU) and BrdU, are toxic antimetabolites that cause DNA instability, necr... Read More Source: PubMed 2011 Dec 6 The dual mTORC1 and mTORC2 inhibitor AZD8055 has anti-tumor activity in acute myeloid leukemia. Willems L, Chapuis N, Puissant A, Maciel TT, Green AS, Jacque N, Vignon C, Park S, Guichard S, Herault O, Fricot A, Hermine O, Moura IC, Auberger P, Ifrah N, Dreyfus F, Bonnet D, Lacombe C, Mayeux P, Bouscary D, Tamburini J 1] Institut Cochin, Université Paris Descartes, CNRS (UMR8104), Paris, France [2] Inserm, U1016, Paris, France [3] Service de Médecine Interne-UF d'Hématologie, Hôpital Cochin, AP-HP, Paris, France. The serine/threonine kinase mammalian target of rapamycin (mTOR) is crucial for cell growth and proliferation, and is constitutively activated in prim... Read More Source: PubMed 2011 Nov 30 Drug solubilization and in vitro toxicity evaluation of lipoamino acid surfactants. Ménard N, Tsapis N, Poirier C, Arnauld T, Moine L, Lefoulon F, Péan JM, Fattal E Technologie Servier, 25-27 rue Eugčne Vignat, 45000 Orléans, France; Univ Paris-Sud, UMR CNRS 8612, Faculté de Pharmacie, 5, rue J.B. Clément, 92296 Châtenay-Malabry Cedex, France; CNRS UMR 8612, 5, rue J.B. Clément, 92296 Châtenay-Malabry Cedex, France. To improve solubilization of a water insoluble anticancer drug, novel surfactants were synthesized. All surfactants derived from lysine, with a so-cal... Read More Source: PubMed 2011 Dec 3 Aptamer-conjugated and drug-loaded acoustic droplets for ultrasound theranosis. Wang CH, Kang ST, Lee YH, Luo YL, Huang YF, Yeh CK Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, 101, Section 2, Kuang-Fu Road, Hsinchu 30013, Taiwan, ROC. Tumor therapy requires multi-functional treatment strategies with specific targeting of therapeutics to reduce general toxicity and increase efficacy.... Read More Source: PubMed Prague Med Rep Ameliorative Effects of Curcumin on the Spermatozoon Tail Length, Count, Motility and Testosterone Serum Level in Metronidazole-treated Mice. Karbalay-Doust S, Noorafshan A Histomorphometry and Stereology Research Centre, Shiraz University of Medical Sciences, Shiraz, Iran. Metronidazole (MTZ) is used as an antiparasitic drug. Curcumin is considered as anti-oxidant and anti-inflammatory agent. The ameliorative e... Read More Source: PubMed 2011 Dec 5 Natural polyphenols in cancer therapy. Asensi M, Ortega A, Mena S, Feddi F, Estrela JM Department of Physiology, University of Valencia , Valencia , Spain. Natural polyphenols are secondary metabolites of plants involved in defense against different types of stress. Extracts containing these compounds hav... Read More Source: PubMed Attenuation of Cytotoxic Natural Product DNA Intercalating Agents by Caffeine. Hill GM, Moriarity DM, Setzer WN Department of Chemistry, University of Alabama in Huntsville, Huntsville, Alabama 35899, USA. Many anti-tumor drugs function by intercalating into DNA. The xanthine alkaloid caffeine can also intercalate into DNA as well as form p-p molecular c... Read More Source: PubMed Am. J. Trop. Med. Hyg. Review: improving the therapeutic index of 8-aminoquinolines by the use of drug combinations: review of the literature and proposal for future investigations. Myint HY, Berman J, Walker L, Pybus B, Melendez V, Baird JK, Ohrt C Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, Maryland; National Center for Natural Products Research and Department of Pharmacology, School of Pharmacy, University of Mississippi, University, Mississippi; Eijkman-Oxford Clinical Research Unit, Jalan Diponegoro No. 69, Jakarta, Indonesia; Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom. Abstract. Because 8-aminoquinolines affect critical survival stages of Plasmodium parasites, treatment and control of malaria could be markedly improv... Read More Source: PubMed 2011 Dec 6 Modified Natural Clinoptilolite Detoxifies Small Mammal's Organism Loaded with Lead II: Genetic, Cell, and Physiological Effects. Topashka-Ancheva M, Beltcheva M, Metcheva R, Rojas JA, Rodriguez-De la Fuente AO, Gerasimova T, Rodríguez-Flores LE, Teodorova SE Institute of Biodiversity and Ecosystem Research, Bulgarian Academy of Sciences, 1, Tzar Osvoboditel Blvd., 1000, Sofia, Bulgaria. The detoxification capacity of the clinoptilolite modification KLS-10-MA used as food additive in small mammals, chronically lead-exposed, was proven ... Read More Source: PubMed N. Z. Med. J. Over-the-counter codeine analgesic misuse and harm: characteristics of cases in Australia and New Zealand. McAvoy BR, Dobbin MD, Tobin CL Tasmanian Department of Health and Human Services, Alcohol and Drug Services, Level 2, Carruthers Building, St Johns Park, New Town, Hobart, Tasmania 7008, Australia. brian.mcavoy@dhhs.tas.gov.au. To describe the characteristics of clients addicted to over-the-counter (OTC) codeine analgesics presenting to an Auckland open-access clinic, and to ... Read More Source: PubMed 2011 Dec 5 Dynamic metabolic labeling of DNA in vivo with arabinosyl nucleosides. Neef AB, Luedtke NW Institute of Organic Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland. Commonly used metabolic labels for DNA, including 5-ethynyl-2'-deoxyuridine (EdU) and BrdU, are toxic antimetabolites that cause DNA instability, necr... Read More Source: PubMed 2011 Dec 6 The dual mTORC1 and mTORC2 inhibitor AZD8055 has anti-tumor activity in acute myeloid leukemia. Willems L, Chapuis N, Puissant A, Maciel TT, Green AS, Jacque N, Vignon C, Park S, Guichard S, Herault O, Fricot A, Hermine O, Moura IC, Auberger P, Ifrah N, Dreyfus F, Bonnet D, Lacombe C, Mayeux P, Bouscary D, Tamburini J 1] Institut Cochin, Université Paris Descartes, CNRS (UMR8104), Paris, France [2] Inserm, U1016, Paris, France [3] Service de Médecine Interne-UF d'Hématologie, Hôpital Cochin, AP-HP, Paris, France. The serine/threonine kinase mammalian target of rapamycin (mTOR) is crucial for cell growth and proliferation, and is constitutively activated in prim... Read More Source: PubMed 2011 Nov 30 Drug solubilization and in vitro toxicity evaluation of lipoamino acid surfactants. Ménard N, Tsapis N, Poirier C, Arnauld T, Moine L, Lefoulon F, Péan JM, Fattal E Technologie Servier, 25-27 rue Eugčne Vignat, 45000 Orléans, France; Univ Paris-Sud, UMR CNRS 8612, Faculté de Pharmacie, 5, rue J.B. Clément, 92296 Châtenay-Malabry Cedex, France; CNRS UMR 8612, 5, rue J.B. Clément, 92296 Châtenay-Malabry Cedex, France. To improve solubilization of a water insoluble anticancer drug, novel surfactants were synthesized. All surfactants derived from lysine, with a so-cal... Read More Source: PubMed |
| Share it! |  |
 |
 |
 |
 |
 |
 |
|
|
Comment & Contribute
| Citing this Health Article | ||||||
|
||||||
| News on Drug Toxicity |
|
Reactions to HIV Drug Have Autoimmune Cause: AIDS Journal |
|
Women Gaining Momentum in Mexican Drug Cartels |
|
Anti-Psychotic Drug Terminates Cancer Stem Cells Devoid of Side Effects: Study |
|
Drug for Irregular Heartbeat Gets Green Signal |
|
Schizophrenia Drug Differentiates Cancer Stem Cells into Less Threatening Cells |
| Total News Item 5375 | |
Are you a member of Facebook? Become a fan of Medindia and get breaking news delivered to your Facebook page.
