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Latest Publication and Research on Down Syndrome

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  2011 Dec 6  

More academics in regular schools? The effect of regular versus special school placement on academic skills in Dutch primary school students with Down syndrome.

de Graaf G, van Hove G, Haveman M

Department of Orthopedagogics, Ghent University, Ghent, Belgium Dutch Down Syndrome Foundation, Meppel, the Netherlands Faculty of Rehabilitation Sciences, University of Dortmund, Dortmund, Germany.

Background Studies from the UK have shown that children with Down syndrome acquire more academic skills in regular education. Does this likewise hold... Read More

Source: PubMed

PLoS ONE    

Characterization of PTZ-Induced Seizure Susceptibility in a Down Syndrome Mouse Model That Overexpresses CSTB.

Brault V, Martin B, Costet N, Bizot JC, Hérault Y

Department of Translational Medicine and Neurogenetics, Institut de Génétique Biologie Moléculaire et Cellulaire (IGBMC), Inserm U596, CNRS UMR7104, Université de Strasbourg, Illkirch, France.

Down syndrome (DS) is a complex genetic syndrome characterized by intellectual disability, dysmorphism and variable additional physiological traits. C... Read More

Source: PubMed

  2011 Nov 23  

How is reward sensitivity related to bodyweight in children?

Verbeken S, Braet C, Lammertyn J, Goossens L, Moens E

Department of Developmental, Personality and Social Psychology, Ghent University, H. Dunantlaan 2, 9000 Ghent, Belgium.

Previous research assumes that there are two seemingly opposing hypotheses for the relation between reward sensitivity (RS) and bodyweight: hyper-resp... Read More

Source: PubMed

    

Morbidity and hospitalizations of adults with Down syndrome.

Tenenbaum A, Chavkin M, Wexler ID, Korem M, Merrick J

Department of Pediatrics, Hadassah Hebrew University Medical Centers, Mt. Scopus campus, Jerusalem, Israel.

Over the last decade a significant increase in the life expectancy of people with Down syndrome (DS) has been observed, which has caused a higher inci... Read More

Source: PubMed

  2011 Nov 17  

Proteomic alteration of Marc-145 cells and PAMs after infection by porcine reproductive and respiratory syndrome virus.

Li Y, Li ZJ, Li YG, Liu CJ, Zhang YP, Ding Z

Key Laboratory of Zoonosis, Ministry of Education, Institute of Zoonosis, Jilin University, Changchun 130062, PR China.

Viral infections usually result in alterations in the host cell proteome, which determine the fate of infected cells and the progress of pathogenesis.... Read More

Source: PubMed

  2011 Dec 2  

Identification and functional characterization of a primate specific E2F1 binding motif regulating MCPH1 expression.

Shi L, Su B

State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Kunming, PR China Kunming Primate Research Centre, Chinese Academy of Sciences, Kunming, PR China Graduate School of Chinese Academy of Sciences, Beijing, PR China.

MCPH1 (also named BRIT1) is one of the known genes responsible for autosomal recessive primary microcephaly (small head syndrome), suggesting its impo... Read More

Source: PubMed

J Multidiscip Healthc    

A systematic review of randomized controlled trials on exercise parameters in the treatment of patellofemoral pain: what works?

Harvie D, O'Leary T, Kumar S

International Centre for Allied Health Evidence (iCAHE), City East Campus, University of South Australia, Adelaide, Australia.

There is research evidence which supports the effectiveness of exercise in reducing pain and increasing function in patients with patellofemoral pain ... Read More

Source: PubMed

  2011 Nov 29  

Improving Circulatory Disturbance in Transient Abnormal Myelopoiesis.

Koga H, Miyako K, Suga N, Hidaka T, Takahashi N

Department of Pediatrics, National Hospital Organization Beppu Medical Center, Oita, Japan.

Transient abnormal myelopoiesis (TAM) in neonates with Down syndrome (DS) is characterized by circulating blast cells in the blood. TAM usually resolv... Read More

Source: PubMed

  2011 Dec 6  

More academics in regular schools? The effect of regular versus special school placement on academic skills in Dutch primary school students with Down syndrome.

de Graaf G, van Hove G, Haveman M

Department of Orthopedagogics, Ghent University, Ghent, Belgium Dutch Down Syndrome Foundation, Meppel, the Netherlands Faculty of Rehabilitation Sciences, University of Dortmund, Dortmund, Germany.

Background Studies from the UK have shown that children with Down syndrome acquire more academic skills in regular education. Does this likewise hold... Read More

Source: PubMed

PLoS ONE    

Characterization of PTZ-Induced Seizure Susceptibility in a Down Syndrome Mouse Model That Overexpresses CSTB.

Brault V, Martin B, Costet N, Bizot JC, Hérault Y

Department of Translational Medicine and Neurogenetics, Institut de Génétique Biologie Moléculaire et Cellulaire (IGBMC), Inserm U596, CNRS UMR7104, Université de Strasbourg, Illkirch, France.

Down syndrome (DS) is a complex genetic syndrome characterized by intellectual disability, dysmorphism and variable additional physiological traits. C... Read More

Source: PubMed

  2011 Nov 23  

How is reward sensitivity related to bodyweight in children?

Verbeken S, Braet C, Lammertyn J, Goossens L, Moens E

Department of Developmental, Personality and Social Psychology, Ghent University, H. Dunantlaan 2, 9000 Ghent, Belgium.

Previous research assumes that there are two seemingly opposing hypotheses for the relation between reward sensitivity (RS) and bodyweight: hyper-resp... Read More

Source: PubMed

    

Implicit and explicit olfactory memory in people with and without Down syndrome.

Johns A, Homewood J, Stevenson R, Taylor A

Department of Psychology, Macquarie University, Sydney, NSW 2109, Australia.

This study examined differences in implicit and explicit memory performance between people with Down syndrome (DS), their siblings, children matched o... Read More

Source: PubMed

  2011 Nov 22  

Up-regulation of NDRG2 through nuclear factor-kappa B is required for Leydig cell apoptosis in both human and murine infertile testes.

Li T, Hu J, He GH, Li Y, Zhu CC, Hou WH, Zhang S, Li W, Zhang JS, Wang Z, Liu XP, Yao LB, Zhang YQ

Department of Histology and Embryology, The Fourth Military Medical University, Xi'an 710032, China.

Many pro-apoptotic factors, such as nuclear factor-kappa B (NF-?B) and Fas, play crucial roles in the process of Leydig cell apoptosis, ultimately lea... Read More

Source: PubMed

    

Implicit and explicit olfactory memory in people with and without Down syndrome.

Johns A, Homewood J, Stevenson R, Taylor A

Department of Psychology, Macquarie University, Sydney, NSW 2109, Australia.

This study examined differences in implicit and explicit memory performance between people with Down syndrome (DS), their siblings, children matched o... Read More

Source: PubMed

  2011 Nov 22  

Up-regulation of NDRG2 through nuclear factor-kappa B is required for Leydig cell apoptosis in both human and murine infertile testes.

Li T, Hu J, He GH, Li Y, Zhu CC, Hou WH, Zhang S, Li W, Zhang JS, Wang Z, Liu XP, Yao LB, Zhang YQ

Department of Histology and Embryology, The Fourth Military Medical University, Xi'an 710032, China.

Many pro-apoptotic factors, such as nuclear factor-kappa B (NF-?B) and Fas, play crucial roles in the process of Leydig cell apoptosis, ultimately lea... Read More

Source: PubMed

    

Morbidity and hospitalizations of adults with Down syndrome.

Tenenbaum A, Chavkin M, Wexler ID, Korem M, Merrick J

Department of Pediatrics, Hadassah Hebrew University Medical Centers, Mt. Scopus campus, Jerusalem, Israel.

Over the last decade a significant increase in the life expectancy of people with Down syndrome (DS) has been observed, which has caused a higher inci... Read More

Source: PubMed

  2011 Nov 17  

Proteomic alteration of Marc-145 cells and PAMs after infection by porcine reproductive and respiratory syndrome virus.

Li Y, Li ZJ, Li YG, Liu CJ, Zhang YP, Ding Z

Key Laboratory of Zoonosis, Ministry of Education, Institute of Zoonosis, Jilin University, Changchun 130062, PR China.

Viral infections usually result in alterations in the host cell proteome, which determine the fate of infected cells and the progress of pathogenesis.... Read More

Source: PubMed

  2011 Dec 2  

Identification and functional characterization of a primate specific E2F1 binding motif regulating MCPH1 expression.

Shi L, Su B

State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Kunming, PR China Kunming Primate Research Centre, Chinese Academy of Sciences, Kunming, PR China Graduate School of Chinese Academy of Sciences, Beijing, PR China.

MCPH1 (also named BRIT1) is one of the known genes responsible for autosomal recessive primary microcephaly (small head syndrome), suggesting its impo... Read More

Source: PubMed

J Multidiscip Healthc    

A systematic review of randomized controlled trials on exercise parameters in the treatment of patellofemoral pain: what works?

Harvie D, O'Leary T, Kumar S

International Centre for Allied Health Evidence (iCAHE), City East Campus, University of South Australia, Adelaide, Australia.

There is research evidence which supports the effectiveness of exercise in reducing pain and increasing function in patients with patellofemoral pain ... Read More

Source: PubMed

  2011 Nov 29  

Improving Circulatory Disturbance in Transient Abnormal Myelopoiesis.

Koga H, Miyako K, Suga N, Hidaka T, Takahashi N

Department of Pediatrics, National Hospital Organization Beppu Medical Center, Oita, Japan.

Transient abnormal myelopoiesis (TAM) in neonates with Down syndrome (DS) is characterized by circulating blast cells in the blood. TAM usually resolv... Read More

Source: PubMed


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Posted by:  johncenawwe  Posted on: 04/18/2012
Yes, If we diagnosis the down syndrome at early stage we can improve the Longevity and Metformin also a good medicine in this same category who treats Type II diabetes and effective in weight loss treatment also.



Posted by:  sanjitta  Posted on: 08/23/2011
mr Ram, i am a new member,i found your words nothing is impossible in this fast developing world, gives me more confidence



Posted by:  Rammohan.R  Posted on: 06/10/2011
Physio therapy,speech therapy, occupational and behavioural therapies are needed to speed up the mile stones in the growth of DS children. Homoeo treatment also helps in improving their brain related functioning.DS children will be very affectionate and very cute. Treatment/therapies should be started as early as possible to get better results. Hope, a day will come, when Down Syndrome in children and adults will be permanently cured. Nothing is impossible in this fast developing world because of the technological innovations made possbile by computers etc.




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