Ther Innov Regul Sci
Investigation of Approval Trends and Benefits of New Fixed-Dose Combination Drugs in Japan.
Kikuchi C, Ohno M, Izumo T, Takahashi S, Aoki M, Shimomura H, Kawano Y, Shimada S, Aoyama T
New fixed-dose combination drugs (FDCs) had been developed in limited numbers in Japan. Since regulatory requirements were relaxed in 2005, 73 new FDC ...
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Source: PubMed
Cardiol Ther 2020 Feb 01
Antihypertensive Effectiveness of Perindopril Arginine and Indapamide Single-Pill Combination According to Body Mass Index: Findings from the FORSAGE Study.
Glezer MG
Overweight and obesity are increasing worldwide and are associated with an increased risk for cardiovascular disease (CVD). The aim of this study was ...
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Source: PubMed
Front Endocrinol (Lausanne)
Hypothyroidism: Cardiovascular Endpoints of Thyroid Hormone Replacement.
Stamatouli A, Bedoya P, Yavuz S
Thyroid dysfunction, either thyrotoxicosis or hypothyroidism, represents an important cardiovascular risk factor. Heart disease is the leading cause o ...
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Source: PubMed
J Cardiovasc Imaging
Echocardiographic Screening Methods for Pulmonary Hypertension: A Practical Review.
Jang AY, Shin MS
Pulmonary hypertension (PH) is a debilitating condition defined as mean pulmonary arterial pressure (mPAP) = 25 mmHg. The importance of impaired right ...
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Source: PubMed
Curr Hypertens Rev 2020 Jan 29
Effects of an Antihypertensive Combination in Japanese Hypertensive Outpatients Based on the Long-Acting Calcium Channel Blocker Benidipine on Vascular and Renal Events: A Sub-Analysis of the COPE Trial.
Umemoto S, Ogihara T, Matsuzaki M, Rakugi H, Shimada K, Hayashi K, Makino H, Ohashi Y, Saruta T
In the trial known as COPE (Combination Therapy of Hypertension to Prevent Cardiovascular Events) three benidipine (a calcium channel blocker; CCB) re ...
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Source: PubMed
