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Latest Publication and Research on Clinical Trials

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Perspect Clin Res    

Quality of clinical trials: A moving target.

Bhatt A

President, Clininvent Research Pvt. Ltd., Everest Chambers, Mumbai, India.

Quality of clinical trials depends on data integrity and subject protection. Globalization, outsourcing and increasing complexicity of clinical trials... Read More

Source: PubMed

Perspect Clin Res    

Survival analysis in clinical trials: Basics and must know areas.

Singh R, Mukhopadhyay K

Department of Community Medicine, College of Medicine and JNM Hospital, Kalyani, West Bengal, India.

Many clinical trials involve following patients for a long time. The primary event of interest in those studies is death, relapse, adverse drug reacti... Read More

Source: PubMed

Perspect Clin Res    

Survival analysis in clinical trials: Basics and must know areas.

Singh R, Mukhopadhyay K

Department of Community Medicine, College of Medicine and JNM Hospital, Kalyani, West Bengal, India.

Many clinical trials involve following patients for a long time. The primary event of interest in those studies is death, relapse, adverse drug reacti... Read More

Source: PubMed

PLoS ONE    

Pre-Clinical Assessment of Novel Multivalent MSP3 Malaria Vaccine Constructs.

Bang G, Prieur E, Roussilhon C, Druilhe P

Malaria Vaccine Development Laboratory, Institut Pasteur, and Vac4all initiative, Paris, France.

MSP3 has been shown to induce protection against malaria in African children. The characterization of a family of Plasmodium falciparum merozoite surf... Read More

Source: PubMed

Front Cell Neurosci    

New perspectives in amblyopia therapy on adults: a critical role for the excitatory/inhibitory balance.

Baroncelli L, Maffei L, Sale A

Institute of Neuroscience, National Research Council Pisa, Italy.

Amblyopia is the most common form of impairment of visual function affecting one eye, with a prevalence of about 1-5% of the total world population. T... Read More

Source: PubMed

  2011 Dec 5  

Ganetespib, a unique triazolone-containing Hsp90 inhibitor, exhibits potent antitumor activity and a superior safety profile for cancer therapy.

Ying W, Du Z, Sun L, Foley KP, Proia DA, Blackman RK, Zhou D, Inoue T, Tatsuta N, Sang J, Ye S, Acquaviva J, Shin Ogawa L, Wada Y, Barsoum J, Koya K

1Chemistry, Synta Pharmaceuticals Corp.

Targeted inhibition of the molecular chaperone heat shock protein 90 (Hsp90) results in the simultaneous blockade of multiple oncogenic signaling path... Read More

Source: PubMed

  2011 Dec 5  

A Comparison of 3 Regimens to Prevent Nevirapine Resistance Mutations in HIV-Infected Pregnant Women Receiving a Single Intrapartum Dose of Nevirapine.

Van Dyke RB, Ngo-Giang-Huong N, Shapiro DE, Frenkel L, Britto P, Roongpisuthipong A, Beck IA, Yuthavisuthi P, Prommas S, Puthanakit T, Achalapong J, Chotivanich N, Rasri W, Cressey TR, Maupin R, Mirochnick M, Jourdain G

Department of Pediatrics, Tulane University Health Sciences Center.

Background. Intrapartum single-dose (SD) nevirapine (NVP) reduces perinatal transmission of human immunodeficiency virus (HIV) infection but selects f... Read More

Source: PubMed

Am. J. Trop. Med. Hyg.    

Long-term albendazole effectiveness for hepatic cystic echinococcosis.

Salinas JL, Gonzales HV, Astuvilca J, Arce-Villavicencio Y, Carbajal-Gonzalez D, Talledo L, Willig JH

Department of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama; Instituto de Medicina Tropical "Daniel A. Carrión" Universidad Nacional Mayor de San Marcos, Lima, Perú; Sociedad Científica de San Fernando, Universidad Nacional Mayor de San Marcos, Lima, Perú

Abstract. Little is known about the long-term effectiveness of albendazole in the medical therapy of non-complicated hepatic cystic echinococcosis (HC... Read More

Source: PubMed

Am. J. Trop. Med. Hyg.    

Nurturing the global workforce in clinical research: the national institutes of health fogarty international clinical scholars and fellows program.

Heimburger DC, Carothers CL, Gardner P, Primack A, Warner TL, Vermund SH

Institute for Global Health, and Fogarty International Clinical Research Scholars and Fellows Support Center at Vanderbilt University, Nashville, Tennessee; Stony Brook University School of Medicine, Stony Brook, New York; Fogarty International Center, National Institutes of Health, Bethesda, Maryland.

Abstract. The Fogarty International Clinical Research Scholars and Fellows Program's goal is to foster the next generation of clinical investigators a... Read More

Source: PubMed

Am. J. Trop. Med. Hyg.    

Adaptive trial design: could we use this approach to improve clinical trials in the field of global health?

Lang T

Global Health Clinical Trials Programme, Centre for Tropical Medicine, University of Oxford, Oxford, United Kingdom.

Abstract. We need more clinical trials in the world's poorest regions to evaluate new drugs and vaccines, and also to find better ways to manage healt... Read More

Source: PubMed

J Gene Med    

Long-term functional adeno-associated virus-microdystrophin expression in the dystrophic CXMDj dog.

Koo T, Okada T, Athanasopoulos T, Foster H, Takeda S, Dickson G

SWAN Institute of Biomedical and Life Sciences, School of Biological Sciences, Royal Holloway University of London, Egham, Surrey, UK.

Duchenne muscular dystrophy (DMD) is a severe, inherited, muscle-wasting disorder caused by mutations in the dystrophin gene. Preclinical studies of a... Read More

Source: PubMed

Perspect Clin Res    

Quality of clinical trials: A moving target.

Bhatt A

President, Clininvent Research Pvt. Ltd., Everest Chambers, Mumbai, India.

Quality of clinical trials depends on data integrity and subject protection. Globalization, outsourcing and increasing complexicity of clinical trials... Read More

Source: PubMed

PLoS ONE    

Pre-Clinical Assessment of Novel Multivalent MSP3 Malaria Vaccine Constructs.

Bang G, Prieur E, Roussilhon C, Druilhe P

Malaria Vaccine Development Laboratory, Institut Pasteur, and Vac4all initiative, Paris, France.

MSP3 has been shown to induce protection against malaria in African children. The characterization of a family of Plasmodium falciparum merozoite surf... Read More

Source: PubMed

Front Cell Neurosci    

New perspectives in amblyopia therapy on adults: a critical role for the excitatory/inhibitory balance.

Baroncelli L, Maffei L, Sale A

Institute of Neuroscience, National Research Council Pisa, Italy.

Amblyopia is the most common form of impairment of visual function affecting one eye, with a prevalence of about 1-5% of the total world population. T... Read More

Source: PubMed

  2011 Dec 5  

Ganetespib, a unique triazolone-containing Hsp90 inhibitor, exhibits potent antitumor activity and a superior safety profile for cancer therapy.

Ying W, Du Z, Sun L, Foley KP, Proia DA, Blackman RK, Zhou D, Inoue T, Tatsuta N, Sang J, Ye S, Acquaviva J, Shin Ogawa L, Wada Y, Barsoum J, Koya K

1Chemistry, Synta Pharmaceuticals Corp.

Targeted inhibition of the molecular chaperone heat shock protein 90 (Hsp90) results in the simultaneous blockade of multiple oncogenic signaling path... Read More

Source: PubMed

  2011 Dec 5  

A Comparison of 3 Regimens to Prevent Nevirapine Resistance Mutations in HIV-Infected Pregnant Women Receiving a Single Intrapartum Dose of Nevirapine.

Van Dyke RB, Ngo-Giang-Huong N, Shapiro DE, Frenkel L, Britto P, Roongpisuthipong A, Beck IA, Yuthavisuthi P, Prommas S, Puthanakit T, Achalapong J, Chotivanich N, Rasri W, Cressey TR, Maupin R, Mirochnick M, Jourdain G

Department of Pediatrics, Tulane University Health Sciences Center.

Background. Intrapartum single-dose (SD) nevirapine (NVP) reduces perinatal transmission of human immunodeficiency virus (HIV) infection but selects f... Read More

Source: PubMed

Am. J. Trop. Med. Hyg.    

Long-term albendazole effectiveness for hepatic cystic echinococcosis.

Salinas JL, Gonzales HV, Astuvilca J, Arce-Villavicencio Y, Carbajal-Gonzalez D, Talledo L, Willig JH

Department of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama; Instituto de Medicina Tropical "Daniel A. Carrión" Universidad Nacional Mayor de San Marcos, Lima, Perú; Sociedad Científica de San Fernando, Universidad Nacional Mayor de San Marcos, Lima, Perú

Abstract. Little is known about the long-term effectiveness of albendazole in the medical therapy of non-complicated hepatic cystic echinococcosis (HC... Read More

Source: PubMed

Am. J. Trop. Med. Hyg.    

Nurturing the global workforce in clinical research: the national institutes of health fogarty international clinical scholars and fellows program.

Heimburger DC, Carothers CL, Gardner P, Primack A, Warner TL, Vermund SH

Institute for Global Health, and Fogarty International Clinical Research Scholars and Fellows Support Center at Vanderbilt University, Nashville, Tennessee; Stony Brook University School of Medicine, Stony Brook, New York; Fogarty International Center, National Institutes of Health, Bethesda, Maryland.

Abstract. The Fogarty International Clinical Research Scholars and Fellows Program's goal is to foster the next generation of clinical investigators a... Read More

Source: PubMed

Am. J. Trop. Med. Hyg.    

Adaptive trial design: could we use this approach to improve clinical trials in the field of global health?

Lang T

Global Health Clinical Trials Programme, Centre for Tropical Medicine, University of Oxford, Oxford, United Kingdom.

Abstract. We need more clinical trials in the world's poorest regions to evaluate new drugs and vaccines, and also to find better ways to manage healt... Read More

Source: PubMed

J Gene Med    

Long-term functional adeno-associated virus-microdystrophin expression in the dystrophic CXMDj dog.

Koo T, Okada T, Athanasopoulos T, Foster H, Takeda S, Dickson G

SWAN Institute of Biomedical and Life Sciences, School of Biological Sciences, Royal Holloway University of London, Egham, Surrey, UK.

Duchenne muscular dystrophy (DMD) is a severe, inherited, muscle-wasting disorder caused by mutations in the dystrophin gene. Preclinical studies of a... Read More

Source: PubMed


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Posted by:  galbotrix  Posted on: 10/17/2011
Hello I’m the son of a Cancer patient. I’ve 2 boxes of Inj Iscador available for cancer treatment which I could not use for my father. Iscador is a recognized therapy for Cancer treatment to balance the side effects of Chemo and other standard treatment options. Researched and manufactured in Europe, the Injections are normally prescribed by most Cancer specialist Homeopaths and a few Oncologists. These injections have to be taken regularly over a period of 2-3 months for the desired effects. But one can consult a fellow Homeopath for the exact medications. In India, these inj have to be imported from Waleda and are available only at a few select places. The available medications are 2 boxes each of Iscador Q Series 0 and 1 @ Rs. 4500/- per box. Please read : http://www.iscador.com for more details. Also consult Dr. Kasad [Mumbai] or Dr. Navneet Rastogi (Delhi) for more info. Mail me : sniphadkar@gmail.com for more details



Posted by:  appu10  Posted on: 09/07/2011
good guidance in simple language!!!!!!!



Posted by:  delmon54  Posted on: 12/31/2009
I want to start a cancer support group here at a village near Madurai, to conduct free medical check-ups, guide cancer patients like where they to go for treatment, whom to contact, how to go there, where they can get free treatment or where assistance could be got etc. Those who are already doing this kind of help to cancer patients can please guide me how to run a similar cancer support group in this village near Madurai. Please contact Gurumoorthi, thanks.



Posted by:  guest  Posted on: 09/17/2008
We are a group of anti- cancer healers and counsellors , our mission being , allow the fullest co-operation of the patient with the Specialists/Physicians for reducing the side-effects, reduce pains , ease digestion etc. All that we need is a photogragh of the patient and theh details of treatments and updations to our mail i d. Don belive us until you see the effects of our hard work . 'Service to patients with big C is service to God ' our motto .


Posted by:  guest  Posted on: 08/14/2010
my dad has been diagonised with stage 3 lung cancer he is undergoing radiation n chemo he is 63 years,please give me some tips about what has to be done treatment was started on 2nd august 2010.




Posted by:  guest  Posted on: 05/29/2008
What are the side effects that occur as a result of the new treatment/ drug




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