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Clinical Trials / Drug Trials- The Past and The Future

Latest Publication and Research on Clinical Trials - The Past and The Future

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  2011 Dec 5  

New challenges in endpoints for drug development in advanced melanoma.

Ribas A, Hersey P, Middleton MR, Gogas HJ, Flaherty KT, Sondak VK, Kirkwood JM

Department of Medicine, Division of Hematology-Oncology, Jonsson Comprehensive Cancer Center, UCLA.

During the past three decades, the field of clinical research for the treatment of advanced melanoma lacked significant advances. Available drugs had ... Read More

Source: PubMed

  2011 Dec 3  

Targeted Therapies in Metastatic Renal Cell Carcinoma: Overview of the Past Year.

Gross-Goupil M, Massard C, Ravaud A

Centre Hospitalo-Universitaire, Hôpital Saint André, 01 Rue Jean Burguet, 33075, Bordeaux, France, marine.gross-goupil@chu-bordeaux.fr.

During the past half-decade, clinical trials have permitted major progress in treatment of metastatic renal cell carcinoma with the first generation o... Read More

Source: PubMed

Expert Rev Anticancer Ther    

What is the reference cytotoxic regimen for advanced gastric cancer: standard versus optimal therapy?

Sohal DP, Sun W

Department of Medicine, Hematology-Oncology Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19103, USA.

Advanced gastric cancer is an aggressive disease, with continued poor clinical outcomes. In the past two decades, many clinical trials have been condu... Read More

Source: PubMed

  2011 Dec 3  

Targeted Therapies in Metastatic Renal Cell Carcinoma: Overview of the Past Year.

Gross-Goupil M, Massard C, Ravaud A

Centre Hospitalo-Universitaire, Hôpital Saint André, 01 Rue Jean Burguet, 33075, Bordeaux, France, marine.gross-goupil@chu-bordeaux.fr.

During the past half-decade, clinical trials have permitted major progress in treatment of metastatic renal cell carcinoma with the first generation o... Read More

Source: PubMed

Expert Rev Anticancer Ther    

What is the reference cytotoxic regimen for advanced gastric cancer: standard versus optimal therapy?

Sohal DP, Sun W

Department of Medicine, Hematology-Oncology Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19103, USA.

Advanced gastric cancer is an aggressive disease, with continued poor clinical outcomes. In the past two decades, many clinical trials have been condu... Read More

Source: PubMed

Expert Rev Anti Infect Ther    

Lung injury induced by sepsis: lessons learned from large animal models and future directions for treatment.

Sadowitz B, Roy S, Gatto LA, Habashi N, Nieman G

Department of Surgery, SUNY Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210, USA.

Acute lung injury (ALI) and the acute respiratory distress syndrome (ARDS) remain common complications of sepsis. Unfortunately, development of effect... Read More

Source: PubMed

Expert Rev Anti Infect Ther    

Lung injury induced by sepsis: lessons learned from large animal models and future directions for treatment.

Sadowitz B, Roy S, Gatto LA, Habashi N, Nieman G

Department of Surgery, SUNY Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210, USA.

Acute lung injury (ALI) and the acute respiratory distress syndrome (ARDS) remain common complications of sepsis. Unfortunately, development of effect... Read More

Source: PubMed

Scott Med J    

The Scottish Liver Transplant Unit: current and future perspectives.

McNally SJ, Wigmore SJ

Scottish Liver Transplant Unit, Royal Infirmary of Edinburgh, 51 Little France Crescent, Edinburgh EH16 4SA, Scotland, UK.

The Scottish Liver Transplant Unit (SLTU) opened in 1992 and has now performed over 900 liver transplants. During this time there have been major chan... Read More

Source: PubMed

Scott Med J    

The Scottish Liver Transplant Unit: current and future perspectives.

McNally SJ, Wigmore SJ

Scottish Liver Transplant Unit, Royal Infirmary of Edinburgh, 51 Little France Crescent, Edinburgh EH16 4SA, Scotland, UK.

The Scottish Liver Transplant Unit (SLTU) opened in 1992 and has now performed over 900 liver transplants. During this time there have been major chan... Read More

Source: PubMed

Korean J Hematol    

Treatment of chronic graft-versus-host disease: Past, present and future.

Martin PJ, Inamoto Y, Carpenter PA, Lee SJ, Flowers ME

Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

Chronic GVHD was recognized as a complication of allogeneic hematopoietic cell transplantation more than 30 years ago, but progress has been slowed by... Read More

Source: PubMed

Korean J Hematol    

Treatment of chronic graft-versus-host disease: Past, present and future.

Martin PJ, Inamoto Y, Carpenter PA, Lee SJ, Flowers ME

Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

Chronic GVHD was recognized as a complication of allogeneic hematopoietic cell transplantation more than 30 years ago, but progress has been slowed by... Read More

Source: PubMed

  2011 Nov 8  

Targeting cognitive deficits in schizophrenia: a review of the development of a new class of medicines from the perspective of community mental health researchers.

Tcheremissine OV, Castro MA, Gardner DR

Carolinas HealthCare System-Behavioral Health Center , Department of Psychiatry , 501 Billingsley Road, Charlotte, NC , USA +1 704 446 7504 ; +1 704 446 7505 ; Oleg.Tcheremissine@carolinas.org.

Introduction: Schizophrenia is a chronic disorder associated with positive and negative symptoms and wide-ranging deficits in neurocognitive function... Read More

Source: PubMed

  2011 Nov 8  

Targeting cognitive deficits in schizophrenia: a review of the development of a new class of medicines from the perspective of community mental health researchers.

Tcheremissine OV, Castro MA, Gardner DR

Carolinas HealthCare System-Behavioral Health Center , Department of Psychiatry , 501 Billingsley Road, Charlotte, NC , USA +1 704 446 7504 ; +1 704 446 7505 ; Oleg.Tcheremissine@carolinas.org.

Introduction: Schizophrenia is a chronic disorder associated with positive and negative symptoms and wide-ranging deficits in neurocognitive function... Read More

Source: PubMed

Curr. Opin. Immunol.    

Diabetogenic T lymphocytes in human Type 1 diabetes.

Roep BO, Peakman M

Department of Immunohematology and Blood Transfusion, Leiden University Medical Centre, Leiden, The Netherlands.

The field of Type 1 diabetes research has been quick to embrace the era of translational medicine in the recent epoch. Building upon some 30 years of ... Read More

Source: PubMed

Curr. Opin. Immunol.    

Diabetogenic T lymphocytes in human Type 1 diabetes.

Roep BO, Peakman M

Department of Immunohematology and Blood Transfusion, Leiden University Medical Centre, Leiden, The Netherlands.

The field of Type 1 diabetes research has been quick to embrace the era of translational medicine in the recent epoch. Building upon some 30 years of ... Read More

Source: PubMed

Bone Marrow Res    

Oncolytic virotherapy for multiple myeloma: past, present, and future.

Thirukkumaran CM, Morris DG

Department of Oncology, Tom Baker Cancer Centre, 1331 29 Street NW, Calgary, AB, Canada T2N 4N1.

Multiple myeloma (MM) is a B-cell malignancy that is currently felt to be incurable. Despite recently approved novel targeted treatments such as lenal... Read More

Source: PubMed

Bone Marrow Res    

Oncolytic virotherapy for multiple myeloma: past, present, and future.

Thirukkumaran CM, Morris DG

Department of Oncology, Tom Baker Cancer Centre, 1331 29 Street NW, Calgary, AB, Canada T2N 4N1.

Multiple myeloma (MM) is a B-cell malignancy that is currently felt to be incurable. Despite recently approved novel targeted treatments such as lenal... Read More

Source: PubMed

Curr Opin Crit Care    

Timing, dose and mode of dialysis in acute kidney injury.

Ricci Z, Ronco C

aDepartment of Pediatric Cardiac Surgery, Bambino Gesù Children's Hospital, Rome bDepartment of Nephrology, Dialysis and Transplantation, St. Bortolo Hospital cInternational Renal Research Insititute, Vicenza, Italy.

In the past 3 years substantial progress has been made in the field of renal replacement therapy (RRT) for critically ill patients.... Read More

Source: PubMed

Curr Opin Crit Care    

Timing, dose and mode of dialysis in acute kidney injury.

Ricci Z, Ronco C

aDepartment of Pediatric Cardiac Surgery, Bambino Gesù Children's Hospital, Rome bDepartment of Nephrology, Dialysis and Transplantation, St. Bortolo Hospital cInternational Renal Research Insititute, Vicenza, Italy.

In the past 3 years substantial progress has been made in the field of renal replacement therapy (RRT) for critically ill patients.... Read More

Source: PubMed

  2011 Dec 5  

New challenges in endpoints for drug development in advanced melanoma.

Ribas A, Hersey P, Middleton MR, Gogas HJ, Flaherty KT, Sondak VK, Kirkwood JM

Department of Medicine, Division of Hematology-Oncology, Jonsson Comprehensive Cancer Center, UCLA.

During the past three decades, the field of clinical research for the treatment of advanced melanoma lacked significant advances. Available drugs had ... Read More

Source: PubMed


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Posted by:  ArpitTrivedi  Posted on: 07/17/2010
Hi everyone. I need some guidance from all Clinical Research experts. I want to pursue a course : "Masters in Clinical Research : MSCR" offered by ICRI-MUSC. It is a 2 year course, 1st year course by ICRI Global Research and 2nd year course by Medical University of South Carolina. Is this a genuine course or some sort of gamble? Please give your valuable guidance. I have completed my MSc in Biochemistry this year in India.



Posted by:  cresenti(Guest)  Posted on: 06/26/2010

CLINICAL RESEARCH IS ADVANCING DAY BY DAY AS THE NEW FORM OF VIRUSES STAGES ON THIS WORLD EVERY OTHER DAY ... STUDY OF CLINICAL RESEARCH WILL HAVE A GTREAT CAREER



Posted by:  Rahul123(Guest)  Posted on: 04/02/2010
Yes, clinical research is a growing industry in India at the moment. I am a BSc Biochem and want to make my career in this field. I recently joined James Lind Institute for my clinical research course and I hope to get placed somewhere soon.
Rahul Jain



Posted by:  harshit(Guest)  Posted on: 10/09/2009
There is a need of good clinical researcher professionals as India is going to be major hub of clinical trial industry. This can be achieved by educating medical professionals, researchers and graduates on Good Clinical Practice, Ethical conduct of the trial, discouraging fabrication of data and following timelines.



Posted by:  Harshit1_pls(Guest)  Posted on: 08/02/2009
Good Morning!

I am Dr. Harshit Mehta working as an associated project manager at Pro Life Sciences Pvt. Ltd. a full service CRO based in Delhi.

I would like to mention here is that with the amount of work increasing in clinical research in india, we would definitely require more qualified and competent professional for this field.

It will become mandatory to do a degree or a certified course in clinical research in future.

So people who want to pursue their career in clinical research, start looking for reliable institute and courses to enhance your capabilities.


Posted by:  guest  Posted on: 10/14/2009
I am Graduate in Clinical research in Uk and currently doing MSc in Clinical Reaserch Administration from University of Liverpool, and i would like to make my career in India, so anyone please suggest me that how can i join indian based CRO and what would be starting salary? Thanks




Posted by:  SeeJay(Guest)  Posted on: 06/01/2009
There is a dire need for a vast majority of doctors in every stream of medicine to acquire specialised knowledge about clinical research in order to help the pharma industry discover newer drugs and bring them into the market to manage health of the people. Anovus Institute of Clinical Resarch in Chandigarh is the newest addition, north of Delhi, to start certification programme for the working physicians to acquire skill and knowledge in clinical research while graduates from life sciences can opt for six month or one year diploma programme.




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