Latest Publications and Research on Chikungunya
Characterization of chikungunya virus infection of a human keratinocyte cell line: Role of mosquito salivary gland protein in suppressing the host immune response.
Puiprom O, Vargas RE, Potiwat R, Chaichana P, Ikuta K, Ramasoota P, Okabayashi T
Mahidol-Osaka Center for Infectious Diseases (MOCID), Faculty of Tropical Medicine, Mahidol University, Ratchathewi, Bangkok, Thailand.
The chikungunya virus (CHIKV) is a mosquito-borne virus that has recently re-emerged in several countries. On infection, the first vertebrate cells to... Read More
Structural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralization.
Sun S, Xiang Y, Akahata W, Holdaway H, Pal P, Zhang X, Diamond MS, Nabel GJ, Rossmann MG
Department of Biological Sciences , Purdue University , West Lafayette , United States.
A 5.3 Å resolution, cryo-electron microscopy (cryoEM) map of Chikungunya virus-like particles (VLPs) has been interpreted using the previously publish... Read More
Clin. Microbiol. Infect. 2013 Apr 10
Public health significance of invasive mosquitoes in Europe.
Schaffner F, Medlock JM, Van Bortel W
Avia-GIS, Agro-Veterinary Information and Analysis, Zoersel, Belgium; Vector Entomology Unit, Institute of Parasitology, Vetsuisse Faculty, University of Zürich, Zürich, Switzerland.
There are currently five invasive Aedes mosquito species known to be established in Europe, namely Aedes albopictus, Aedes aegypti, Aedes japonicus, A... Read More
Am. J. Trop. Med. Hyg. 2013 Apr 8
The Role of Innate versus Adaptive Immune Responses in a Mouse Model of O'Nyong-Nyong Virus Infection.
Seymour RL, Rossi SL, Bergren NA, Plante KS, Weaver SC
Institute for Human Infections and Immunity, Center for Tropical Diseases, and Department of Pathology, University of Texas Medical Branch, Galveston, Texas.
O'nyong-nyong virus (ONNV), an alphavirus closely related to chikungunya virus (CHIKV), has caused three major epidemics in Africa since 1959. The ONN... Read More
PLoS Negl Trop Dis
A Wolbachia wMel Transinfection in Aedes albopictus Is Not Detrimental to Host Fitness and Inhibits Chikungunya Virus.
Blagrove MS, Arias-Goeta C, Di Genua C, Failloux AB, Sinkins SP
University of Oxford, Peter Medawar Building for Pathogen Research and Departments of Medicine (NDM)/Zoology, Oxford, United Kingdom.
BACKGROUND: Wolbachia inherited intracellular bacteria can manipulate the reproduction of their insect hosts through cytoplasmic incompatibility (CI),... Read More
PLoS Negl Trop Dis
Chikungunya Virus-associated Long-term Arthralgia: A 36-month Prospective Longitudinal Study.
Schilte C, Staikovsky F, Couderc T, Madec Y, Carpentier F, Kassab S, Albert ML, Lecuit M, Michault A
Unité Immunobiologie des Cellules Dendritiques, Department of Immunology, Institut Pasteur, Paris, France ; Institut National de la Santé et de la Recherche Médicale (INSERM) U818, Paris, France.
BACKGROUND: Arthritogenic alphaviruses, including Chikungunya virus (CHIKV), are responsible for acute fever and arthralgia, but can also lead to chro... Read More
PLoS Negl Trop Dis
Evidence of Habitat Structuring Aedes albopictus Populations in Réunion Island.
Delatte H, Toty C, Boyer S, Bouetard A, Bastien F, Fontenille D
Maladies Infectieuses et Vecteurs: Ecologie, Génétique, Evolution et Contrôle, Institut de Recherche pour le Développement 224, Centre National de la Recherche Scientifique 5290, Universités Montpellier 1 & 2, Montpellier, France ; CIRAD, UMR PVBMT, F-97410 Saint-Pierre, La Réunion, France.
Arbovirus vector dynamics and spread are influenced by climatic, environmental and geographic factors. Major Chikungunya and Dengue fever outbreaks oc... Read More
A mathematical model of chikungunya dynamics and control: the major epidemic on réunion island.
Yakob L, Clements AC
School of Population Health, University of Queensland, Brisbane, Queensland, Australia.
Chikungunya is a re-emerging arboviral disease transmitted by Aedes spp. mosquitoes. Although principally endemic to Africa and Asia, recent outbreaks... Read More
J. Virol. 2013 Apr 3
Chikungunya Virus Host-Range E2-Transmembrane Deletion Mutants Induce Protective Immunity Against Challenge in C57BL/6J Mice.
Piper A, Ribeiro M, Smith KM, Briggs CM, Huitt E, Nanda K, Spears CJ, Quiles M, Cullen J, Thomas ME, Brown DT, Hernandez R
Department of Molecular and Structural Biochemistry, 128, Polk Hall, North Carolina State University, Raleigh, NC 27695, USA.
A vaccine against Chikungunya virus (ChikV), a re-emerging pathogenic arbovirus, has been made by attenuating wild type (WT) virus via truncation of t... Read More
Germline excision of transgenes in Aedes aegypti by homing endonucleases.
Aryan A, Anderson MA, Myles KM, Adelman ZN
Fralin Life Science Institute and Department of Entomology, Virginia Tech, Blacksburg, VA 24061.
Aedes (Ae.) aegypti is the primary vector for dengue viruses (serotypes1-4) and chikungunya virus. Homing endonucleases (HEs) are ancient selfish elem... Read More